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Microbiology

D-Index
65
Citations
31470
World Ranking
2459
National Ranking
142

Overview

Serge Lebecque is affiliated with Claude Bernard University Lyon 1 in France. Their research spans primarily the fields of Biochemistry, Genetics and Molecular Biology, with significant overlap into Immunology and Microbiology. Lebecque's work encompasses several subfields including Immunology, Molecular Biology, Genetics, Computational Theory and Mathematics, and Oncology.

The main topics of their research focus on immune response and inflammation, estrogen and related hormone effects, reproductive system and pregnancy, melanoma and MAPK pathways, computational drug discovery methods, cytokine signaling pathways and interactions, as well as mechanisms and regulation of cell death.

Lebecque has contributed to the academic community through publications in several scientific venues. These include:

  • Journal of Inflammation Research
  • Nature Communications
  • Scientific Reports
  • Life Science Alliance

Some of their recent papers are:

  • "A Gender-Dependent Molecular Switch of Inflammation via MyD88/Estrogen Receptor-Alpha Interaction" (2021), Journal of Inflammation Research
  • "Caspase-8 deficiency induces a switch from TLR3 induced apoptosis to lysosomal cell death in neuroblastoma" (2021), Scientific Reports
  • "The hexosamine pathway and coat complex II promote malignant adaptation to nutrient scarcity" (2022), Life Science Alliance
  • "Targeting ERK-MYD88 interaction leads to ERK dysregulation and immunogenic cancer cell death" (2024), Nature Communications

Lebecque frequently collaborates with other researchers in the field. Notable coauthors include:

  • Serge N. Manié
  • Toufic Renno
  • Mélanie Bonnet
  • Nader Hussein
  • François Virard

Best Publications

  • Immunobiology of Dendritic Cells

    Jacques Banchereau;Francine Briere;Christophe Caux;Jean Davoust

  • Selective Recruitment of Immature and Mature Dendritic Cells by Distinct Chemokines Expressed in Different Anatomic Sites

    Marie-Caroline Dieu;Béatrice Vanbervliet;Alain Vicari;Jean-Michel Bridon

  • T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines.

    F Fossiez;O Djossou;P Chomarat;L Flores-Romo

  • Langerin, a Novel C-Type Lectin Specific to Langerhans Cells, Is an Endocytic Receptor that Induces the Formation of Birbeck Granules

    Jenny Valladeau;Odile Ravel;Colette Dezutter-Dambuyant;Kevin Moore

  • Long-Term Survival for Patients With Non–Small-Cell Lung Cancer With Intratumoral Lymphoid Structures

    Marie-Caroline Dieu-Nosjean;Martine Antoine;Claire Danel;Didier Heudes

  • Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking

    Gwendalyn J. Randolph;Sylvie Beaulieu;Serge Lebecque;Ralph M. Steinman

  • Up-Regulation of Macrophage Inflammatory Protein-3α/CCL20 and CC Chemokine Receptor 6 in Psoriasis

    Bernhard Homey;Marie-Caroline Dieu-Nosjean;Andrea Wiesenborn;Catherine Massacrier

  • In Breast Carcinoma Tissue, Immature Dendritic Cells Reside within the Tumor, Whereas Mature Dendritic Cells Are Located in Peritumoral Areas

    Diana Bell;Pascale Chomarat;Denise Broyles;George Netto

  • TLR3 can directly trigger apoptosis in human cancer cells.

    Bruno Salaun;Isabelle Coste;Marie-Clotilde Rissoan;Serge J. Lebecque

  • Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88.

    Uzma Hasan;Claire Chaffois;Claude Gaillard;Virginie Saulnier

  • A Novel Lysosome-Associated Membrane Glycoprotein, DC-LAMP, Induced upon DC Maturation, Is Transiently Expressed in MHC Class II Compartment

    B de Saint-Vis;J Vincent;S Vandenabeele;B Vanbervliet

  • Dendritic cell infiltration and prognosis of early stage breast cancer.

    Isabelle Treilleux;Jean-Yves Blay;Nathalie Bendriss-Vermare;Isabelle Ray-Coquard

  • Macrophage Inflammatory Protein 3α Is Expressed at Inflamed Epithelial Surfaces and Is the Most Potent Chemokine Known in Attracting Langerhans Cell Precursors

    Marie-Caroline Dieu-Nosjean;Catherine Massacrier;Bernhard Homey;Béatrice Vanbervliet

  • Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice.

    Eric Tartour;François Fossiez;Isabelle Joyeux;Annie Galinha

  • Within Germinal Centers, Isotype Switching of Immunoglobulin Genes Occurs after the Onset of Somatic Mutation

    Yong Jun Liu;Florence Malisan;Odette de Bouteiller;Christiane Guret

  • Dendritic cells infiltrating human non-small cell lung cancer are blocked at immature stage.

    Ivan Perrot;Dominique Blanchard;Nathalie Freymond;Sylvie Isaac

  • APCs Express DCIR, a Novel C-Type Lectin Surface Receptor Containing an Immunoreceptor Tyrosine-Based Inhibitory Motif

    Elizabeth E. M. Bates;Nathalie Fournier;Eric Garcia;Jenny Valladeau

  • Interleukin-17 activates human renal epithelial cells in vitro and is expressed during renal allograft rejection.

    C Van Kooten;J G Boonstra;M E Paape;F Fossiez

  • Regulation of dendritic cell trafficking: a process that involves the participation of selective chemokines

    Marie-Caroline Dieu-Nosjean;Alain Vicari;Serge Lebecque;Christophe Caux

  • Human Langerhans Cells Express a Specific TLR Profile and Differentially Respond to Viruses and Gram-Positive Bacteria

    Vincent Flacher;Marielle Bouschbacher;Estelle Verronèse;Catherine Massacrier

Frequent Co-Authors

Sem Saeland
Sem Saeland Schering-Plough
Christophe Caux
Christophe Caux Cancer Center of Lyon
Yong-Jun Liu
Yong-Jun Liu University of Washington
Francine Brière
Francine Brière Baylor Scott & White Health
Pierre Golstein
Pierre Golstein Aix-Marseille University
Rudolf Valenta
Rudolf Valenta Medical University of Vienna
Dominique Valeyre
Dominique Valeyre Université Paris Cité
Jean Davoust
Jean Davoust Université Paris Cité

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