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Immunology

D-Index
84
Citations
23514
World Ranking
1393
National Ranking
92

Overview

Peter Brossart is affiliated with the University Hospital Bonn in Germany. Their research focuses extensively on medicine, with significant contributions bridging oncology, immunology, rheumatology, hematology, and molecular biology. The core of their work centers on cancer immunotherapy and biomarkers, immunotherapy and immune responses, multiple myeloma treatments, immune cell function and interaction, CAR-T cell therapy research, vasculitis and related conditions, and spondyloarthritis studies and treatments.

Brossart has coauthored numerous publications, frequently collaborating with researchers such as Valentin Sebastian Schäfer, Charlotte Behning, Annkristin Heine, Pantelis Karakostas, and Tobias A.W. Holderried.

Their recent published papers include the following:

  • The Role of Antigen Spreading in the Efficacy of Immunotherapies, 2020, Clinical Cancer Research
  • G-quadruplexes: a promising target for cancer therapy, 2021, Molecular Cancer
  • Clinical and immunological effects of mRNA vaccines in malignant diseases, 2021, Molecular Cancer
  • Towards new horizons: characterization, classification and implications of the tumour antigenic repertoire, 2020, Nature Reviews Clinical Oncology
  • High-risk additional chromosomal abnormalities at low blast counts herald death by CML, 2020, Leukemia

Brossart has published in a range of scientific venues, showing consistent contribution to:

  • Annals of the Rheumatic Diseases
  • Leukemia
  • Blood
  • Frontiers in Immunology
  • Ultraschall in der Medizin - European Journal of Ultrasound

The main fields of their studies cover medicine broadly, with subfields as listed:

  • Oncology
  • Immunology
  • Rheumatology
  • Hematology
  • Molecular Biology

The specific topics addressed in their research include:

  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Multiple Myeloma Research and Treatments
  • Immune Cell Function and Interaction
  • CAR-T cell therapy research
  • Vasculitis and related conditions
  • Spondyloarthritis Studies and Treatments

Best Publications

  • Retraction: Regression of human metastatic renal cell carcinoma after vaccination with tumor cell-dendritic cell hybrids.

    Alexander Kugler;Gernot Stuhler;Peter Walden;Gerhard Zöller

  • Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells.

    Peter Brossart;Stefan Wirths;Gernot Stuhler;Volker L. Reichardt

  • Identification of HLA-A2–Restricted T-Cell Epitopes Derived From the MUC1 Tumor Antigen for Broadly Applicable Vaccine Therapies

    Peter Brossart;Kathrin S. Heinrich;Gernot Stuhler;Lars Behnke

  • G-quadruplexes: a promising target for cancer therapy.

    Nils Kosiol;Stefan Juranek;Peter Brossart;Annkristin Heine

  • Differential impact of allelic ratio and insertion site in FLT3-ITD-positive AML with respect to allogeneic transplantation.

    Richard F Schlenk;Sabine Kayser;Lars Bullinger;Guido Kobbe

  • Improved Outcomes With Retinoic Acid and Arsenic Trioxide Compared With Retinoic Acid and Chemotherapy in Non-High-Risk Acute Promyelocytic Leukemia: Final Results of the Randomized Italian-German APL0406 Trial.

    Uwe Platzbecker;Giuseppe Avvisati;Laura Cicconi;Christian Thiede

  • Her-2/neu-derived Peptides Are Tumor-associated Antigens Expressed by Human Renal Cell and Colon Carcinoma Lines and Are Recognized by in Vitro Induced Specific Cytotoxic T Lymphocytes

    Peter Brossart;Gernot Stuhler;Thomas Flad;Stefan Stevanovic

  • Survivin is a shared tumor-associated antigen expressed in a broad variety of malignancies and recognized by specific cytotoxic T cells.

    Susanne M. Schmidt;Kerstin Schag;Martin R. Müller;Markus M. Weck

  • Sorafenib, but not sunitinib, affects function of dendritic cells and induction of primary immune responses.

    Madeleine M. Hipp;Norbert Hilf;Steffen Walter;Daniela Werth

  • The JAK-inhibitor ruxolitinib impairs dendritic cell function in vitro and in vivo

    Annkristin Heine;Stefanie Andrea Erika Held;Solveig Nora Daecke;Stephanie Wallner

  • Assessment of imatinib as first-line treatment of chronic myeloid leukemia: 10-year survival results of the randomized CML study IV and impact of non-CML determinants

    Rüdiger Hehlmann;Michael Lauseker;Susanne Saußele;Markus Pfirrmann

  • Dendritic Cell Immunogenicity Is Regulated by Peroxisome Proliferator-Activated Receptor γ

    Alessio Nencioni;Frank Grünebach;Anke Zobywlaski;Claudio Denzlinger

  • Immunologic and clinical responses after vaccinations with peptide-pulsed dendritic cells in metastatic renal cancer patients.

    Jan Wierecky;Martin R. Müller;Stefan Wirths;Edith Halder-Oehler

  • Proteasome inhibitors: antitumor effects and beyond.

    A Nencioni;F Grünebach;F Patrone;A Ballestrero

  • The epithelial tumor antigen MUC1 is expressed in hematological malignancies and is recognized by MUC1-specific cytotoxic T-lymphocytes.

    Peter Brossart;Anya Schneider;Patricia Dill;Theodora Schammann

  • RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features.

    V I Gaidzik;V Teleanu;E Papaemmanuil;D Weber

  • PPAR-γ agonists inhibit toll-like receptor-mediated activation of dendritic cells via the MAP kinase and NF-κB pathways

    Silke Appel;Valdete Mirakaj;Anita Bringmann;Markus M. Weck

  • Monocyte-derived dendritic cells are permissive to the complete replicative cycle of human cytomegalovirus.

    S. Riegler;H. Hebart;H. Einsele;P. Brossart

  • Intradermal Vaccinations With RNA Coding for TAA Generate CD8+ and CD4+ Immune Responses and Induce Clinical Benefit in Vaccinated Patients

    Susanne M Rittig;Maik Haentschel;Katrin J Weimer;Annkristin Heine

  • Generation of Functional Human Dendritic Cells From Adherent Peripheral Blood Monocytes by CD40 Ligation in the Absence of Granulocyte-Macrophage Colony-Stimulating Factor

    Peter Brossart;Frank Grünebach;Gernot Stuhler;Volker L. Reichardt

  • The use of dendritic cells in cancer immunotherapy

    Alessio Nencioni;Frank Grünebach;Susanne M. Schmidt;Martin R. Müller

Frequent Co-Authors

Frank Grünebach
Frank Grünebach University of Tübingen
Lothar Kanz
Lothar Kanz University of Tübingen
Alessio Nencioni
Alessio Nencioni University of Genoa
Arnold Ganser
Arnold Ganser Hannover Medical School
Hartmut Goldschmidt
Hartmut Goldschmidt University Hospital Heidelberg
Hartmut Döhner
Hartmut Döhner University of Ulm
Hans-Georg Rammensee
Hans-Georg Rammensee University of Tübingen
Richard F. Schlenk
Richard F. Schlenk University Hospital Heidelberg
Anna Jauch
Anna Jauch Heidelberg University
Glen Kristiansen
Glen Kristiansen University Hospital Bonn

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