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Gohta Goshima

Gohta Goshima

Nagoya University
Japan

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Mitosis
  • Spindle apparatus

Gohta Goshima spends much of his time researching Kinetochore, Cell biology, Spindle apparatus, Spindle pole body and Spindle checkpoint. His Kinetochore research focuses on Centromere and how it connects with Heterochromatin and Heterochromatin protein 1. Gohta Goshima mostly deals with Dynein in his studies of Cell biology.

As part of his studies on Spindle apparatus, he often connects relevant areas like Mitosis. His Spindle pole body research incorporates elements of Microtubule organizing center, Prometaphase, Multipolar spindles and Microtubule. His biological study spans a wide range of topics, including Metaphase, Anaphase and Centrosome.

His most cited work include:

  • Functional genomic screen reveals genes involved in lipid-droplet formation and utilization (522 citations)
  • Kinesin and dynein move a peroxisome in vivo: a tug-of-war or coordinated movement? (518 citations)
  • Genes required for mitotic spindle assembly in Drosophila S2 cells. (458 citations)

What are the main themes of his work throughout his whole career to date?

Gohta Goshima focuses on Cell biology, Microtubule, Mitosis, Spindle apparatus and Kinetochore. His Cell biology study combines topics in areas such as Anaphase, Spindle pole body, Cytokinesis and Physcomitrella patens. His research in Microtubule intersects with topics in Biophysics, Cell division and Cytoplasm.

Gohta Goshima interconnects Asymmetric cell division and Live cell imaging in the investigation of issues within Mitosis. His study in Spindle apparatus is interdisciplinary in nature, drawing from both Microtubule organizing center, Meiosis and Metaphase. The study incorporates disciplines such as Centromere, Kinesin 8 and Multipolar spindles in addition to Kinetochore.

He most often published in these fields:

  • Cell biology (101.64%)
  • Microtubule (76.23%)
  • Mitosis (43.44%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cell biology (101.64%)
  • Microtubule (76.23%)
  • Physcomitrella patens (36.89%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cell biology, Microtubule, Physcomitrella patens, Mitosis and Biophysics. The Cell biology study combines topics in areas such as Cell division, Spindle pole body and Kinetochore. He regularly links together related areas like Cytokinesis in his Kinetochore studies.

His research in Microtubule tackles topics such as Prometaphase which are related to areas like Motor protein and Ectopic expression. As part of his studies on Mitosis, Gohta Goshima frequently links adjacent subjects like Spindle apparatus. In his research, In vivo is intimately related to Cytoplasm, which falls under the overarching field of Biophysics.

Between 2018 and 2021, his most popular works were:

  • Drosophila kinesin-8 stabilizes the kinetochore–microtubule interaction (14 citations)
  • Drosophila kinesin-8 stabilizes the kinetochore–microtubule interaction (14 citations)
  • Transient cotransformation of CRISPR/Cas9 and oligonucleotide templates enables efficient editing of target loci in Physcomitrella patens. (10 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Mitosis
  • Genetics

Gohta Goshima focuses on Physcomitrella patens, Cell biology, Microtubule, Kinetochore and Kinesin. His work deals with themes such as Plant cell and Asymmetric cell division, which intersect with Cell biology. As a member of one scientific family, Gohta Goshima mostly works in the field of Microtubule, focusing on Biophysics and, on occasion, Microtubule dynamics.

His studies in Kinetochore integrate themes in fields like Cell cycle, Aneuploidy, Cytokinesis and Chromosome segregation. The concepts of his Kinesin study are interwoven with issues in Chromosome movement and Mitosis. The various areas that he examines in his Mitosis study include Dynein and Anaphase.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Functional genomic screen reveals genes involved in lipid-droplet formation and utilization

Yi Guo;Tobias C. Walther;Meghana Rao;Nico Stuurman.
Nature (2008)

727 Citations

Kinesin and dynein move a peroxisome in vivo: a tug-of-war or coordinated movement?

Comert Kural;Hwajin Kim;Sheyum Syed;Gohta Goshima.
Science (2005)

696 Citations

Genes required for mitotic spindle assembly in Drosophila S2 cells.

Gohta Goshima;Roy Wollman;Roy Wollman;Sarah S. Goodwin;Nan Zhang.
Science (2007)

570 Citations

The roles of microtubule-based motor proteins in mitosis: comprehensive RNAi analysis in the Drosophila S2 cell line

Gohta Goshima;Ronald D. Vale.
Journal of Cell Biology (2003)

519 Citations

Establishing biorientation occurs with precocious separation of the sister kinetochores, but not the arms, in the early spindle of budding yeast.

Gohta Goshima;Mitsuhiro Yanagida.
Cell (2000)

412 Citations

Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle

Gohta Goshima;Mirjam Mayer;Mirjam Mayer;Nan Zhang;Nico Stuurman;Nico Stuurman.
Journal of Cell Biology (2008)

384 Citations

A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1

Chikashi Obuse;Osamu Iwasaki;Tomomi Kiyomitsu;Gohta Goshima;Gohta Goshima.
Nature Cell Biology (2004)

317 Citations

Length control of the metaphase spindle

Gohta Goshima;Roy Wollman;Roy Wollman;Nico Stuurman;Nico Stuurman;Jonathan M. Scholey.
Current Biology (2005)

293 Citations

Proper metaphase spindle length is determined by centromere proteins Mis12 and Mis6 required for faithful chromosome segregation

Gohta Goshima;Shigeaki Saitoh;Mitsuhiro Yanagida.
Genes & Development (1999)

291 Citations

Mechanisms for focusing mitotic spindle poles by minus end-directed motor proteins.

Gohta Goshima;François Nédélec;Ronald D. Vale.
Journal of Cell Biology (2005)

284 Citations

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