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Olivier Delattre

Olivier Delattre

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Genetics
France
2026
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Genetics and Molecular Biology
France
2024

D-Index & Metrics

Genetics

D-Index
122
Citations
61094
World Ranking
347
National Ranking
6

Medicine

D-Index
123
Citations
62242
World Ranking
3318
National Ranking
90

Research.com Recognitions

  • 2026 - Research.com Genetics in France Leader Award
  • 2025 - Research.com Genetics in France Leader Award
  • 2024 - Research.com Genetics in France Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in France Leader Award
  • 2023 - Research.com Genetics in France Leader Award
  • 2012 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Olivier Delattre is affiliated with PSL University in France. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology.

Their work primarily focuses on subfields such as molecular biology, pulmonary and respiratory medicine, cancer research, oncology, and pathology and forensic medicine.

Key topics addressed in their research include:

  • Sarcoma diagnosis and treatment
  • Cancer genomics and diagnostics
  • Neuroblastoma research and treatments
  • Chromatin remodeling and cancer
  • CAR-T cell therapy research
  • RNA research and splicing
  • Cancer mechanisms and therapy

Frequent publication venues for their research include:

  • Cancer Research
  • Neuro-Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Cancers

Prominent recent papers by Olivier Delattre include:

  • Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors, 2020, Nature Medicine
  • Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden, 2021, Nature Communications
  • Transcriptional Programs Define Intratumoral Heterogeneity of Ewing Sarcoma at Single-Cell Resolution, 2020, Cell Reports
  • Failure of human rhombic lip differentiation underlies medulloblastoma formation, 2022, Nature
  • Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma, 2021, Cancer Discovery

Olivier Delattre has collaborated frequently with a group of coauthors, including Didier Surdez, Gaëlle Pierron, Julien Masliah-Planchon, Franck Bourdeaut, and Sylvain Baulande.

In recognition of their scientific contributions, Olivier Delattre has been named a Member of Academia Europaea in 2012 and is also a member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Systematic identification of genomic markers of drug sensitivity in cancer cells

    Mathew J. Garnett;Elena J. Edelman;Sonja J. Heidorn;Christopher Greenman;Christopher Greenman

  • Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

    Olivier Delattre;Jessica Zucman;Béatrice Plougastel;Chantal Desmaze

  • Truncating Mutations of hSNF5/INI1 in Aggressive Paediatric Cancer

    Isabella Versteege;Nicolas Sévenet;Julian Lange;Marie-Françoise Rousseau-Merck

  • Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

    Guy A. Rouleau;Philippe Merel;Mohini Lutchman;Marc Sanson;Marc Sanson

  • Control-FREEC

    Valentina Boeva;Tatiana Popova;Kevin Bleakley;Pierre Chiche

  • The Ewing Family of Tumors -- A Subgroup of Small-Round-Cell Tumors Defined by Specific Chimeric Transcripts

    O Delattre;J Zucman;T Melot;X S Garau

  • Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

    Marcel Kool;Andrey Korshunov;Marc Remke;Marc Remke;David T.W. Jones

  • Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma

    Isabelle Janoueix-Lerosey;Delphine Lequin;Delphine Lequin;Laurence Brugières;Agnès Ribeiro

  • Subgroup-specific structural variation across 1,000 medulloblastoma genomes

    Paul A. Northcott;Paul A. Northcott;David J.H. Shih;John Peacock;Livia Garzia

  • Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome.

    Yoon Jae Cho;Aviad Tsherniak;Pablo Tamayo;Sandro Santagata

  • Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition

    Marcel Kool;David T.W. Jones;Natalie Jäger;Paul A. Northcott

  • Ewing Sarcoma: Current Management and Future Approaches Through Collaboration

    Nathalie Gaspar;Douglas S. Hawkins;Uta Dirksen;Ian J. Lewis

  • Protein interaction mapping: A Drosophila case study

    Etienne Formstecher;Sandra Aresta;Vincent Collura;Alexandre Hamburger

  • Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

    William A. May;Mikhail L. Gishizky;Mikhail L. Gishizky;Stephen L. Lessnick;Lynn B. Lunsford

  • Combinatorial generation of variable fusion proteins in the Ewing family of tumours.

    J Zucman;T Melot;C Desmaze;J Ghysdael

  • Ploidy and Large-Scale Genomic Instability Consistently Identify Basal-like Breast Carcinomas with BRCA1/2 Inactivation

    Tatiana Popova;Elodie Manié;Guillaume Rieunier;Virginie Caux-Moncoutier

  • Evidence for the complete inactivation of the NF2 gene in the majority of sporadic meningiomas

    M H Ruttledge;J Sarrazin;S Rangaratnam;C M Phelan

  • Mesenchymal Stem Cell Features of Ewing Tumors

    Franck Tirode;Karine Laud-Duval;Karine Laud-Duval;Alexandre Prieur;Alexandre Prieur;Bruno Delorme;Bruno Delorme

  • Constitutional mutations of the hSNF5/INI1 gene predispose to a variety of cancers.

    Nicolas Sévenet;Eammon Sheridan;Daniel Amram;Pascale Schneider

  • EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts

    Jessica Zucman;Olivier Delattre;Chantal Desmaze;Alan L. Epstein

Frequent Co-Authors

Jean Michon
Jean Michon Institute Curie
Gilles Thomas
Gilles Thomas Grenoble Alpes University
Alain Aurias
Alain Aurias Institute Curie
Emmanuel Barillot
Emmanuel Barillot Institute Curie
François Doz
François Doz Université Paris Cité
Xavier Sastre-Garau
Xavier Sastre-Garau Institute Curie
Anne Vincent-Salomon
Anne Vincent-Salomon Institute Curie
Odile Oberlin
Odile Oberlin Institut Gustave Roussy
Heinrich Kovar
Heinrich Kovar St Anna Children's Hospital
Khê Hoang-Xuan
Khê Hoang-Xuan Université Paris Cité

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