World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
34440
World Ranking
3254
National Ranking
1646

Medicine

D-Index
84
Citations
34518
World Ranking
14893
National Ranking
7529

Overview

Jaclyn A. Biegel is affiliated with the University of Southern California in the United States. Their research covers a range of topics primarily within medicine, biochemistry, genetics, and molecular biology. The scientist has contributed to multiple subfields, including molecular biology, genetics, infectious diseases, cancer research, and pathology and forensic medicine.

Jaclyn A. Biegel's work addresses several main topics, particularly in cancer genomics and diagnostics, glioma diagnosis and treatment, chromatin remodeling and cancer, SARS-CoV-2 and COVID-19 research, ocular oncology and treatments, acute lymphoblastic leukemia research, and cancer mechanisms and therapy.

The scientist has published in numerous venues. Frequent publication outlets include:

  • Neuro-Oncology
  • Cancer Genetics
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences

Jaclyn A. Biegel's recent papers illustrate a focus both on oncology and infectious diseases. Selected recent papers include:

  • Efficacy of High-Dose Chemotherapy and Three-Dimensional Conformal Radiation for Atypical Teratoid/Rhabdoid Tumor: A Report From the Children's Oncology Group Trial ACNS0333, 2020, Journal of Clinical Oncology
  • Increased viral variants in children and young adults with impaired humoral immunity and persistent SARS-CoV-2 infection: A consecutive case series, 2021, EBioMedicine
  • Establishing the Clinical Utility of ctDNA Analysis for Diagnosis, Prognosis, and Treatment Monitoring of Retinoblastoma: The Aqueous Humor Liquid Biopsy, 2021, Cancers
  • Emerging variants of concern in SARS-CoV-2 membrane protein: a highly conserved target with potential pathological and therapeutic implications, 2021, Emerging Microbes & Infections
  • Spike Protein NTD mutation G142D in SARS-CoV-2 Delta VOC lineages is associated with frequent back mutations, increased viral loads, and immune evasion, 2021, bioRxiv (Cold Spring Harbor Laboratory)

Collaboration and coauthorship play an important role in Jaclyn A. Biegel's research. Frequent coauthors include Xiaowu Gai, Dejerianne Ostrow, Jianling Ji, Alexander R. Judkins, and Li Shen.

Overall, the scientist's published work intersects diverse but related domains, combining clinical oncology research with molecular and genetic approaches, as well as contributions to understanding infectious disease mechanisms, particularly those related to SARS-CoV-2.

Best Publications

  • Mutational heterogeneity in cancer and the search for new cancer-associated genes

    Michael S. Lawrence;Petar Stojanov;Petar Stojanov;Paz Polak;Paz Polak;Paz Polak;Gregory V. Kryukov;Gregory V. Kryukov;Gregory V. Kryukov

  • Prediction of central nervous system embryonal tumour outcome based on gene expression

    Scott L. Pomeroy;Pablo Tamayo;Michelle Gaasenbeek;Lisa M. Sturla

  • Germ-Line and Acquired Mutations of INI1 in Atypical Teratoid and Rhabdoid Tumors

    Jaclyn A. Biegel;Jun-Ying Zhou;Lucy B. Rorke;Cindy Stenstrom

  • Central nervous system atypical teratoid/rhabdoid tumors of infancy and childhood: definition of an entity

    Lucy Balian Rorke;Roger J. Packer;Jaclyn A. Biegel

  • Frequent Expression of a Mutant Epidermal Growth Factor Receptor in Multiple Human Tumors

    David K. Moscatello;Marina Holgado-Madruga;Andrew K. Godwin;Gloria Ramirez

  • The Genetic Landscape of the Childhood Cancer Medulloblastoma

    D. Williams Parsons;D. Williams Parsons;Meng Li;Xiaosong Zhang;Siân Jones

  • Fusion of PAX7 to FKHR by the Variant t(1;13)(p36;q14) Translocation in Alveolar Rhabdomyosarcoma

    Richard J. Davis;Celina M. D'Cruz;Mark A. Lovell;Jaclyn A. Biegel

  • Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma.

    Frederic G. Barr;Naomi Galili;John Holick;John Holick;Jaclyn A. Biegel;Jaclyn A. Biegel

  • Alterations of the hSNF5/INI1 gene in central nervous system atypical teratoid/rhabdoid tumors and renal and extrarenal rhabdoid tumors.

    Jaclyn A. Biegel;Lu Tan;Fan Zhang;Luanne Wainwright

  • Central Nervous System Atypical Teratoid/Rhabdoid Tumor: Results of Therapy in Children Enrolled in a Registry

    Joanne M. Hilden;Sharon Meerbaum;Peter Burger;Jonathan Finlay

  • Intensive multimodality treatment for children with newly diagnosed CNS atypical teratoid rhabdoid tumor

    Susan N. Chi;Mary Ann Zimmerman;Xiaopan Yao;Kenneth J. Cohen

  • A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers

    Ryan S. Lee;Chip Stewart;Scott L. Carter;Lauren Ambrogio

  • Spectrum of SMARCB1/INI1 Mutations in Familial and Sporadic Rhabdoid Tumors

    Katherine W. Eaton;Laura S. Tooke;Luanne M. Wainwright;Alexander R. Judkins;Alexander R. Judkins

  • Immunohistochemical analysis of hSNF5/INI1 in pediatric CNS neoplasms.

    Alexander R Judkins;Joanne Mauger;As Ht;Lucy B Rorke

  • Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas.

    Margaret J. Dougherty;Mariarita Santi;Marcia S. Brose;Changqing Ma

  • Central nervous system atypical teratoid/rhabdoid tumors of infancy and childhood.

    Lucy Balian Rorke;Roger Packer;Jaclyn Biegel

  • SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation

    Xiaofeng Wang;Xiaofeng Wang;Ryan S Lee;Ryan S Lee;Burak H Alver;Jeffrey R Haswell;Jeffrey R Haswell

  • A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3

    White Ps;Maris Jm;Beltinger C;Sulman E

  • Immunohistochemical analysis of hSNF5/INI1 distinguishes renal and extra-renal malignant rhabdoid tumors from other pediatric soft tissue tumors.

    Andrew C Hoot;Pierre Russo;Alexander R Judkins;Elizabeth J Perlman

  • Microdeletions of chromosomal region 22q11 in patients with congenital conotruncal cardiac defects.

    E Goldmuntz;D Driscoll;M L Budarf;E H Zackai

Frequent Co-Authors

Xiaowu Gai
Xiaowu Gai Children's Hospital of Los Angeles
Beverly S. Emanuel
Beverly S. Emanuel Children's Hospital of Philadelphia
Lucy B. Rorke
Lucy B. Rorke Children's Hospital of Philadelphia
Monica Bessler
Monica Bessler Children's Hospital of Philadelphia
Garrett M. Brodeur
Garrett M. Brodeur Children's Hospital of Philadelphia
Hakon Hakonarson
Hakon Hakonarson Children's Hospital of Philadelphia
Charles W. M. Roberts
Charles W. M. Roberts St. Jude Children's Research Hospital
Timothy J. Triche
Timothy J. Triche Van Andel Institute
Leslie N. Sutton
Leslie N. Sutton University of Pennsylvania
John M. Maris
John M. Maris Children's Hospital of Philadelphia

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

A degree in Biology or Biochemistry opens doors to a range of specialized online programs and evolving career options in the health and science fields. For those interested in leadership, an advanced phd in healthcare management can prepare graduates for strategic roles in hospitals, research institutions, and healthcare systems.

For individuals passionate about pharmaceuticals and patient care, online pharmd programs offer a flexible route to become a licensed pharmacist or pursue research-based pharmacy careers. Those drawn to human movement and health promotion may benefit from an online exercise science degree, which prepares students for roles in sports medicine, fitness training, wellness coaching, and rehabilitation.

Similarly, an online kinesiology degree supports students aiming for careers connected to physical therapy, occupational health, or athletic performance enhancement. With the demand for health science professionals on the rise, these online pathways offer flexibility, specialization, and promising employment opportunities for Biology and Biochemistry graduates.

Best Scientists Citing Jaclyn A. Biegel

Trending Scientists