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Molecular Biology

D-Index
52
Citations
12823
World Ranking
2419
National Ranking
1193

Overview

Monica Bessler is affiliated with the Children's Hospital of Philadelphia in the United States. Their research contributions include key work published in 2020, such as the paper titled "Mice with a Mutation in the Mdm2 Gene That Interferes with MDM2/Ribosomal Protein Binding Develop a Defect in Erythropoiesis," which appeared in UNC Libraries. This publication has received citations that indicate engagement within the scientific community.

Their frequent coauthors include:

  • Takuya Kamio
  • Bai-Wei Gu
  • Timothy S. Olson
  • Yanping Zhang
  • Philip J. Mason

Regarding publication venues, Monica Bessler's work has been presented in:

  • UNC Libraries

This research profile identifies a strong collaboration network with multiple coauthors contributing to their projects. This collaborative approach is typical in biomedical research, especially in areas associated with genetic and molecular mechanisms, which aligns with the focus of their known publication on gene mutation and erythropoiesis.

The absence of listed awards, books, main fields of study, subfields of study, or main topics of work suggests that available data is limited, concentrating on specific research output rather than broad disciplinary classification. The research appears to contribute primarily to genetic and hematologic studies, as indicated by the focus on the Mdm2 gene and its role in erythropoiesis, which is the process of red blood cell production.

Monica Bessler's affiliation with a major children's hospital further emphasizes a clinical and biomedical orientation to their work, with potential implications for understanding genetic mutations affecting pediatric hematologic conditions.

Best Publications

  • The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

    Tom Vulliamy;Anna Marrone;Frederick Goldman;Andrew Dearlove

  • Natural history of paroxysmal nocturnal hemoglobinuria.

    Peter Hillmen;S.M. Lewis;Monica Bessler;Lucio Luzzatto

  • Diagnosis and management of paroxysmal nocturnal hemoglobinuria.

    Charles Parker;Mitsuhiro Omine;Stephen Richards;Jun-Ichi Nishimura

  • Effect of the complement inhibitor eculizumab on thromboembolism in patients with paroxysmal nocturnal hemoglobinuria.

    Peter Hillmen;Petra Muus;Ulrich Dührsen;Antonio M. Risitano

  • Diagnosing and treating Diamond Blackfan anaemia: results of an international clinical consensus conference

    Adrianna Vlachos;Sarah Ball;Niklas Dahl;Blanche P. Alter

  • Paroxysmal nocturnal haemoglobinuria (PNH) is caused by somatic mutations in the PIG-A gene.

    M Bessler;P J Mason;P Hillmen;T Miyata

  • Somatic Mutations in Paroxysmal Nocturnal Hemoglobinuria: A Blessing in Disguise?

    Lucio Luzzatto;Monica Bessler;Bruno Rotoli

  • The role of human ribosomal proteins in the maturation of rRNA and ribosome production

    Sara Robledo;Rachel A. Idol;Dan L. Crimmins;Jack H. Ladenson

  • Mouse dyskerin mutations affect accumulation of telomerase RNA and small nucleolar RNA, telomerase activity, and ribosomal RNA processing

    Yuko Mochizuki;Jun He;Shashikant Kulkarni;Monica Bessler

  • Somatic mutations and cellular selection in paroxysmal nocturnal haemoglobinuria.

    M. Bessler;P.J. Mason;P. Hillmen;L. Luzzatto

  • The genetics of dyskeratosis congenita.

    Unknown

  • Dyskeratosis congenita -- a disease of dysfunctional telomere maintenance

    P. J. Mason;D. B. Wilson;M. Bessler

  • Specific defect in N-acetylglucosamine incorporation in the biosynthesis of the glycosylphosphatidylinositol anchor in cloned cell lines from patients with paroxysmal nocturnal hemoglobinuria.

    Peter Hillmen;Monica Bessler;Philip J. Mason;Winifred M. Watkins

  • TERC and TERT gene mutations in patients with bone marrow failure and the significance of telomere length measurements

    Hong Yan Du;Elena Pumbo;Jennifer Ivanovich;Ping An

  • Mutations of the SBDS gene are present in most patients with Shwachman-Diamond syndrome

    Jill R. Woloszynek;Robert J. Rothbaum;Amy S. Rawls;Patrick J. Minx

  • Murine embryonic stem cells without pig-a gene activity are competent for hematopoiesis with the PNH phenotype but not for clonal expansion.

    Vittorio Rosti;Gabi Tremml;Vera Soares;Pier Paolo Pandolfi

  • Cells depleted for RPS19, a protein associated with Diamond Blackfan Anemia, show defects in 18S ribosomal RNA synthesis and small ribosomal subunit production

    Rachel A. Idol;Sara Robledo;Hong-Yan Du;Dan L. Crimmins

  • 3'UTR-truncated Hmga2 cDNA causes MPN-like hematopoiesis by conferring a clonal growth advantage at the level of HSC in mice.

    Kazuhiko Ikeda;Philip J. Mason;Philip J. Mason;Monica Bessler;Monica Bessler

  • Targeted disruption of Dkc1, the gene mutated in X-linked dyskeratosis congenita, causes embryonic lethality in mice.

    Jun He;Sandra Navarrete;Murek Jasinski;Tom Vulliamy

  • Increased sensitivity to complement and a decreased red blood cell life span in mice mosaic for a nonfunctional Piga gene.

    Unknown

Frequent Co-Authors

Philip J. Mason
Philip J. Mason Children's Hospital of Philadelphia
Lucio Luzzatto
Lucio Luzzatto University of Florence
David B. Wilson
David B. Wilson Washington University in St. Louis
Jaclyn A. Biegel
Jaclyn A. Biegel University of Southern California
Peter Hillmen
Peter Hillmen St James's University Hospital
Hubert Schrezenmeier
Hubert Schrezenmeier University of Ulm
Gérard Socié
Gérard Socié Université Paris Cité
Jaroslaw P. Maciejewski
Jaroslaw P. Maciejewski Cleveland Clinic
Jeff Szer
Jeff Szer Peter MacCallum Cancer Centre
Russell P. Rother
Russell P. Rother Tetherex Pharmaceuticals

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