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Chemistry

D-Index
52
Citations
8667
World Ranking
13618
National Ranking
764

Overview

Arasu Ganesan is affiliated with the University of East Anglia in the United Kingdom. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine.

Their work covers a range of fields and subfields, especially focusing on molecular biology, pharmacology, organic chemistry, biotechnology, and oncology. The principal areas of study include histone deacetylase inhibitors research, protein degradation and inhibitors, microbial natural products and biosynthesis, epigenetics and DNA methylation, peptidase inhibition and analysis, marine sponges and natural products, and click chemistry and applications.

Ganesan's recent publications span several journals and topics. Notable papers include:

  • Thirty Years of HDAC Inhibitors: 2020 Insight and Hindsight (2020) in Journal of Medicinal Chemistry
  • Phytochemicals in Drug Discovery-A Confluence of Tradition and Innovation (2024) in International Journal of Molecular Sciences
  • Two-hit wonders: The expanding universe of multitargeting epigenetic agents (2020) in Current Opinion in Chemical Biology
  • New tranylcypromine derivatives containing sulfonamide motif as potent LSD1 inhibitors to target acute myeloid leukemia: Design, synthesis and biological evaluation (2020) in Bioorganic Chemistry
  • Euglenatides, Potent Antiproliferative Cyclic Peptides Isolated from the Freshwater Photosynthetic Microalga Euglena gracilis (2022) in Angewandte Chemie International Edition

Their frequent co-authors include:

  • Simon Gibbons, with 5 joint publications
  • Patience Chihomvu, with 3 joint publications
  • Kevin Woollard, with 3 joint publications
  • Martin A. Hayes, with 3 joint publications
  • Mohammed Aldholmi, with 3 joint publications

Arasu Ganesan's work has been frequently published in venues such as:

  • Journal of Medicinal Chemistry (4 publications)
  • Pure and Applied Chemistry (3 publications)
  • Current Opinion in Chemical Biology (2 publications)
  • Preprints.org (2 publications)
  • Journal of Chemical Education (2 publications)

Best Publications

  • The impact of natural products upon modern drug discovery

    A Ganesan

  • Thirty Years of HDAC Inhibitors: 2020 Insight and Hindsight

    Terence C. S. Ho;Alex H. Y. Chan;A. Ganesan

  • Natural products and combinatorial chemistry: back to the future.

    Jean-Yves Ortholand;A Ganesan

  • Identification of a chemical probe for NAADP by virtual screening

    Edmund Naylor;Abdelilah Arredouani;Sridhar R. Vasudevan;Alexander M. Lewis

  • TPC2 Is a Novel NAADP-sensitive Ca2+ Release Channel, Operating as a Dual Sensor of Luminal pH and Ca2+

    Samantha Jane Pitt;Tim M Funnell;Mano Sitsapesan;Elisa Venturi

  • A biomimetic total synthesis of (-)-spirotryprostatin B and related studies.

    Haishan Wang;A. Ganesan

  • Oral Administration of Peptide-Based Drugs: Beyond Lipinski's Rule.

    Gabriela Bianchi dos Santos;A. Ganesan;Flavio da Silva Emery

  • Total Synthesis of Spiruchostatin A, a Potent Histone Deacetylase Inhibitor

    Alexander Yurek-George;Fay Habens;Matthew Brimmell;Graham Packham

  • Natural products as a hunting ground for combinatorial chemistry.

    A Ganesan

  • Enantioselective synthesis of tranylcypromine analogues as lysine demethylase (LSD1) inhibitors.

    Hanae Benelkebir;Christopher Hodgkinson;Patrick J. Duriez;Annette L. Hayden

  • Strategies for the Dynamic Integration of Combinatorial Synthesis and Screening.

    Arasu Ganesan

  • Ionic liquid acceleration of solid-phase suzuki-miyaura cross-coupling reactions.

    Jefferson D Revell;A Ganesan

  • Solution-phase synthesis of a β-amino alcohol combinatorial library

    Bee Lee Chng;Arasu Ganesan

  • The N-Acyliminium Pictet−Spengler Condensation as a Multicomponent Combinatorial Reaction on Solid Phase and Its Application to the Synthesis of Demethoxyfumitremorgin C Analogues

    Haishan Wang and;A. Ganesan

  • Highly efficient Lewis acid-catalysed Pictet–Spengler reactions discovered by parallel screening

    Natarajan Srinivasan;A. Ganesan

  • Azumamides A–E: Histone Deacetylase Inhibitory Cyclic Tetrapeptides from the Marine Sponge Mycale izuensis

    Yoichi Nakao;Satoru Yoshida;Shigeki Matsunaga;Nobuaki Shindoh

  • The first biologically active synthetic analogues of FK228, the depsipeptide histone deacetylase inhibitor.

    Alexander Yurek-George;Alexander Richard Liam Cecil;Alex Hon Kit Mo;Shijun Wen

  • Total synthesis of the fumiquinazoline alkaloids: solution-phase studies.

    Haishan Wang;A. Ganesan

  • The histone deacetylase inhibitors vorinostat and romidepsin downmodulate IL-10 expression in cutaneous T-cell lymphoma cells.

    C. E. Tiffon;J. E. Adams;L. van der Fits;Shijun Wen

  • Multitarget Drugs: an Epigenetic Epiphany

    A. Ganesan

  • Synthesis and evaluation of tryprostatin B and demethoxyfumitremorgin C analogues.

    Haishan Wang;Takeo Usui;Hiroyuki Osada;A. Ganesan

Frequent Co-Authors

Graham Packham
Graham Packham University of Southampton
Paul A. Townsend
Paul A. Townsend University of Manchester
Kazuo Shin-ya
Kazuo Shin-ya National Institute of Advanced Industrial Science and Technology
Takashi Takahashi
Takashi Takahashi Nagoya University
Peter Johnson
Peter Johnson University of Southampton
Jun K. Yamashita
Jun K. Yamashita Kyoto University
Nobuhiro Fusetani
Nobuhiro Fusetani Waseda University
Grant C. Churchill
Grant C. Churchill University of Oxford
Donna E. Davies
Donna E. Davies University of Southampton
Manfred Jung
Manfred Jung University of Freiburg

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