D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 48 Citations 8,604 98 World Ranking 11202 National Ranking 4858

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

Timothy F. Walseth spends much of his time researching Cyclic ADP-ribose, Biochemistry, ADP-ribosyl Cyclase, NAD+ kinase and Nicotinic acid adenine dinucleotide phosphate. His Cyclic ADP-ribose research integrates issues from Ryanodine receptor, Calcium, Internal medicine, Endocrinology and Second messenger system. The Endocrinology study combines topics in areas such as Calcium in biology and Endoplasmic reticulum, Cell biology.

His research investigates the connection between Biochemistry and topics such as Biophysics that intersect with issues in Calmodulin, Activator and Signal transduction. His work deals with themes such as Amino acid, Cyclase activity, Cyclase, Nucleotide and Stereochemistry, which intersect with ADP-ribosyl Cyclase. His Stereochemistry research is multidisciplinary, incorporating elements of Metabolite and Nicotinamide.

His most cited work include:

  • Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD38 (648 citations)
  • Structural determination of a cyclic metabolite of NAD+ with intracellular Ca2+-mobilizing activity. (432 citations)
  • ADP-ribosyl cyclase and CD38 catalyze the synthesis of a calcium-mobilizing metabolite from NADP. (347 citations)

What are the main themes of his work throughout his whole career to date?

Timothy F. Walseth mainly focuses on Biochemistry, Cyclic ADP-ribose, Cell biology, Endocrinology and Internal medicine. His Cyclic ADP-ribose study combines topics in areas such as Ryanodine receptor, Calcium, Stereochemistry, ADP-ribosyl Cyclase and NAD+ kinase. The various areas that Timothy F. Walseth examines in his ADP-ribosyl Cyclase study include Cyclase activity and NAD+ nucleosidase.

His NAD+ kinase research includes elements of Adenosine and Nicotinamide. His work focuses on many connections between Cell biology and other disciplines, such as Tumor necrosis factor alpha, that overlap with his field of interest in Transfection and Molecular biology. His Endocrinology research incorporates elements of Calcium in biology and G protein.

He most often published in these fields:

  • Biochemistry (38.52%)
  • Cyclic ADP-ribose (31.85%)
  • Cell biology (28.15%)

What were the highlights of his more recent work (between 2011-2021)?

  • Nicotinic acid adenine dinucleotide phosphate (20.00%)
  • Cell biology (28.15%)
  • Biochemistry (38.52%)

In recent papers he was focusing on the following fields of study:

His main research concerns Nicotinic acid adenine dinucleotide phosphate, Cell biology, Biochemistry, Second messenger system and Photoaffinity labeling. His Nicotinic acid adenine dinucleotide phosphate research incorporates themes from Calcium in biology, Adenosine and NAD+ kinase. His study in the fields of Signal transduction, Endosome and GTPase under the domain of Cell biology overlaps with other disciplines such as IL-2 receptor.

Borrowing concepts from Structure–activity relationship, Timothy F. Walseth weaves in ideas under Biochemistry. He studied Second messenger system and Calcium signaling that intersect with Cyclic ADP-ribose. His research in Cyclic ADP-ribose intersects with topics in Respiratory function and Inositol trisphosphate.

Between 2011 and 2021, his most popular works were:

  • Photoaffinity Labeling of Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Targets in Mammalian Cells (120 citations)
  • Expression of Ca2+-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells (89 citations)
  • Photoaffinity labeling of high affinity nicotinic acid adenine dinucleotide phosphate (NAADP)-binding proteins in sea urchin egg. (88 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Amino acid

His primary areas of study are Cell biology, Second messenger system, Two-pore channel, Nicotinic acid adenine dinucleotide phosphate and Photoaffinity labeling. His Cell biology study integrates concerns from other disciplines, such as Molecular biology, Gene expression and Transfection. The concepts of his Second messenger system study are interwoven with issues in Voltage-dependent calcium channel, Inflammation, Endogeny, Kinase and Contractility.

His Two-pore channel research is multidisciplinary, incorporating perspectives in Rab and Interactome. Timothy F. Walseth is investigating Photoaffinity labeling as part of his Biochemistry and Binding site and Photoaffinity labeling study. His study in Binding site is interdisciplinary in nature, drawing from both Nicotinamide, Nicotinamide mononucleotide and NAD+ kinase.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD38

M. Howard;J. C. Grimaldi;J. F. Bazan;F. E. Lund.
Science (1993)

841 Citations

Structural determination of a cyclic metabolite of NAD+ with intracellular Ca2+-mobilizing activity.

Hon Cheung Lee;T. F. Walseth;G. T. Bratt;R. N. Hayes.
Journal of Biological Chemistry (1989)

660 Citations

ADP-ribosyl cyclase and CD38 catalyze the synthesis of a calcium-mobilizing metabolite from NADP.

Robert Aarhus;Richard M. Graeff;Deborah M. Dickey;Timothy F. Walseth.
Journal of Biological Chemistry (1995)

539 Citations

Calcium mobilization by dual receptors during fertilization of sea urchin eggs

Hon Cheung Lee;Robert Aarhus;Timothy F. Walseth.
Science (1993)

416 Citations

Synthesis and characterization of antagonists of cyclic-ADP-ribose-induced Ca2+ release

Timothy F. Walseth;Hon Cheung Lee.
Biochimica et Biophysica Acta (1993)

351 Citations

Enzymatic synthesis and characterizations of cyclic GDP-ribose. A procedure for distinguishing enzymes with ADP-ribosyl cyclase activity.

R. M. Graeff;T. F. Walseth;K. Fryxell;W. D. Branton.
Journal of Biological Chemistry (1994)

337 Citations

Cyclic ADP ribose activation of the ryanodine receptor is mediated by calmodulin

Hon Cheung Lee;Robert Aarhus;Richard M Graeff;Mary E. Gurnack.
Nature (1994)

329 Citations

Similarities in amino acid sequences of Aplysia ADP-ribosyl cyclase and human lymphocyte antigen CD38.

David J. States;Timothy F. Walseth;Hon Cheung Lee.
Trends in Biochemical Sciences (1992)

305 Citations

Activation and Inactivation of Ca Release by NAADP

Robert Aarhus;Deborah M. Dickey;Richard M. Graeff;Kyle R. Gee.
Journal of Biological Chemistry (1996)

243 Citations

Cyclic AMP and LDL trigger a rapid enhancement in gap junction assembly through a stimulation of connexin trafficking

Alicia F. Paulson;Paul D. Lampe;Rita A. Meyer;Erica TenBroek.
Journal of Cell Science (2000)

220 Citations

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