D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 40 Citations 6,927 117 World Ranking 3623 National Ranking 137

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Immune system
  • T cell

Her scientific interests lie mostly in Cytotoxic T cell, Immunology, T cell, T-cell receptor and CD8. As part of the same scientific family, Mirjam H.M. Heemskerk usually focuses on Cytotoxic T cell, concentrating on Immunotherapy and intersecting with Leukemia and Donor lymphocyte infusion. In the field of Immunology, her study on Minor histocompatibility antigen, Spleen, Immune system and Homing overlaps with subjects such as Population.

The various areas that Mirjam H.M. Heemskerk examines in her T cell study include Computational biology and Antigen. Mirjam H.M. Heemskerk combines subjects such as Molecular biology, Adoptive cell transfer, Human leukocyte antigen, Cell biology and CD3 with her study of T-cell receptor. In her work, Natural killer cell is strongly intertwined with Stem cell, which is a subfield of CD8.

Her most cited work include:

  • Mesenchymal stem cells promote engraftment of human umbilical cord blood–derived CD34+ cells in NOD/SCID mice (466 citations)
  • Hematopoiesis-restricted minor histocompatibility antigens HA-1- or HA-2-specific T cells can induce complete remissions of relapsed leukemia. (393 citations)
  • Inhibition of T Cell and Promotion of Natural Killer Cell Development by the Dominant Negative Helix Loop Helix Factor Id3 (261 citations)

What are the main themes of her work throughout her whole career to date?

Mirjam H.M. Heemskerk mainly focuses on Immunology, T cell, Cytotoxic T cell, Antigen and T-cell receptor. Her work carried out in the field of Immunology brings together such families of science as Stem cell and Transplantation. Her T cell study combines topics from a wide range of disciplines, such as Cancer research, Computational biology, Genetic enhancement and CD40.

She studied Antigen and Monoclonal antibody that intersect with B cell. Her T-cell receptor research is multidisciplinary, relying on both Haematopoiesis, Molecular biology, Adoptive cell transfer, Cell biology and CD3. Her Human leukocyte antigen research incorporates elements of MHC class I, CD8, Major histocompatibility complex, Antigen presentation and Peptide.

She most often published in these fields:

  • Immunology (50.57%)
  • T cell (38.07%)
  • Cytotoxic T cell (36.36%)

What were the highlights of her more recent work (between 2015-2021)?

  • Cancer research (23.30%)
  • Immunology (50.57%)
  • T cell (38.07%)

In recent papers she was focusing on the following fields of study:

Mirjam H.M. Heemskerk mostly deals with Cancer research, Immunology, T cell, Antigen and T-cell receptor. Her Immunology research is multidisciplinary, incorporating perspectives in Cytotoxic T cell and Transplantation. Her research investigates the connection between Cytotoxic T cell and topics such as Bone marrow that intersect with issues in Peripheral and Interferon gamma.

Her study in T cell is interdisciplinary in nature, drawing from both Human leukocyte antigen, CD8, CD40 and Cell biology. Her work on Antigen is being expanded to include thematically relevant topics such as Immunotherapy. Her biological study spans a wide range of topics, including Cell culture, Adoptive cell transfer, B cell and Cancer immunotherapy.

Between 2015 and 2021, her most popular works were:

  • Mutated nucleophosmin 1 as immunotherapy target in acute myeloid leukemia. (58 citations)
  • Selective graft-versus-leukemia depends on magnitude and diversity of the alloreactive T cell response (40 citations)
  • PRAME as a Potential Target for Immunotherapy in Metastatic Uveal Melanoma (38 citations)

In her most recent research, the most cited papers focused on:

  • Immune system
  • Gene
  • Antibody

Mirjam H.M. Heemskerk spends much of her time researching Cancer research, Antigen, T-cell receptor, Immunotherapy and T cell. Her Cancer research study incorporates themes from PRAME and Human leukocyte antigen. The subject of her Antigen research is within the realm of Immunology.

Her Immunology research is multidisciplinary, incorporating elements of CD154 and Aspergillus. Her T cell study integrates concerns from other disciplines, such as Virology, Epstein–Barr virus and Stem cell, Cell biology. Her Minor histocompatibility antigen course of study focuses on Donor lymphocyte infusion and Cytotoxic T cell.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mesenchymal stem cells promote engraftment of human umbilical cord blood–derived CD34+ cells in NOD/SCID mice

Willy A Noort;Alwine B Kruisselbrink;Pieternella S in't Anker;Marjolein Kruger.
Experimental Hematology (2002)

653 Citations

Hematopoiesis-restricted minor histocompatibility antigens HA-1- or HA-2-specific T cells can induce complete remissions of relapsed leukemia.

W. A. Erik Marijt;Mirjam H. M. Heemskerk;Freke M. Kloosterboer;Els Goulmy.
Proceedings of the National Academy of Sciences of the United States of America (2003)

527 Citations

Inhibition of T Cell and Promotion of Natural Killer Cell Development by the Dominant Negative Helix Loop Helix Factor Id3

Mirjam H.M. Heemskerk;Bianca Blom;Garry Nolan;Alexander P.A. Stegmann.
Journal of Experimental Medicine (1997)

394 Citations

Allo-HLA reactivity of virus-specific memory T cells is common.

Avital L. Amir;Lloyd J. A. D'Orsogna;Dave L. Roelen;Marleen M. van Loenen.
Blood (2010)

341 Citations

Redirection of antileukemic reactivity of peripheral T lymphocytes using gene transfer of minor histocompatibility antigen HA-2-specific T-cell receptor complexes expressing a conserved alpha joining region.

Mirjam H M Heemskerk;Manja Hoogeboom;Roelof A de Paus;Michel G D Kester.
Blood (2003)

305 Citations

Reprogramming of virus-specific T cells into leukemia-reactive T cells using T cell receptor gene transfer.

Mirjam H.M. Heemskerk;Manja Hoogeboom;Renate S. Hagedoorn;Michel G.D. Kester.
Journal of Experimental Medicine (2004)

277 Citations

Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers.

Sine Reker Hadrup;Sine Reker Hadrup;Arnold H Bakker;Arnold H Bakker;Chengyi J Shu;Rikke S Andersen.
Nature Methods (2009)

273 Citations

Mixed T cell receptor dimers harbor potentially harmful neoreactivity

Marleen M. van Loenen;Renate de Boer;Avital L. Amir;Renate S. Hagedoorn.
Proceedings of the National Academy of Sciences of the United States of America (2010)

251 Citations

Efficiency of T-cell receptor expression in dual-specific T cells is controlled by the intrinsic qualities of the TCR chains within the TCR-CD3 complex

Mirjam H. M. Heemskerk;Renate S. Hagedoorn;Menno A. W. G. van der Hoorn;Lars T. van der Veken.
Blood (2007)

233 Citations

Early stages in the development of human T, natural killer and thymic dendritic cells

H. Spits;B. Blom;A.-C. Jaleco;K. Weijer.
Immunological Reviews (1998)

212 Citations

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Frans H.J. Claas

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Wolfgang Uckert

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Emmanuel J. H. J. Wiertz

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Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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