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Immunology

D-Index
76
Citations
24262
World Ranking
1884
National Ranking
74

Overview

Chiara Bonini is affiliated with Vita-Salute San Raffaele University in Italy. Their research activity spans primarily the fields of Medicine and Immunology and Microbiology, with a notable focus on specialized subfields including Oncology, Immunology, Molecular Biology, Infectious Diseases, and Hematology.

The scientific work of Chiara Bonini encompasses several main topics, which include:

  • CAR-T cell therapy research
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • Hematopoietic Stem Cell Transplantation
  • Biomedical Ethics and Regulation
  • COVID-19 Clinical Research Studies

Their contributions have been published in a variety of frequent venues such as:

  • Frontiers in Immunology
  • Regular and Young Investigator Award Abstracts
  • Cancer Research
  • Blood
  • HemaSphere

Among recent notable publications are the following papers:

  • "Enhancing anti-tumour efficacy with immunotherapy combinations," 2020, The Lancet
  • "Management of adults and children receiving CAR T-cell therapy: 2021 best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE) and the European Haematology Association (EHA)," 2021, Annals of Oncology
  • "IL-1β+ macrophages fuel pathogenic inflammation in pancreatic cancer," 2023, Nature
  • "Immune effector cell-associated hematotoxicity: EHA/EBMT consensus grading and best practice recommendations," 2023, Blood
  • "Disrupting N-glycan expression on tumor cells boosts chimeric antigen receptor T cell efficacy against solid malignancies," 2022, Science Translational Medicine

Chiara Bonini has collaborated frequently with several co-authors, including Fabio Ciceri, Eliana Ruggiero, Monica Casucci, Elena Tassi, and Maddalena Noviello. These collaborations suggest an active engagement within a network of researchers focused on related topics within immunology and hematology.

Best Publications

  • HSV-TK Gene Transfer into Donor Lymphocytes for Control of Allogeneic Graft-Versus-Leukemia

    Chiara Bonini;Giuliana Ferrari;Simona Verzeletti;Paolo Servida

  • Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells

    Margherita Norelli;Barbara Camisa;Giulia Barbiera;Laura Falcone

  • Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells

    Fulvio Mavilio;Graziella Pellegrini;Stefano Ferrari;Francesca Di Nunzio

  • IL-7 and IL-15 instruct the generation of human memory stem T cells from naïve precursors

    Nicoletta Cieri;Barbara Camisa;Fabienne Cocchiarella;Mattia Forcato

  • Targeted genome editing in human repopulating haematopoietic stem cells

    Pietro Genovese;Giulia Schiroli;Giulia Escobar;Tiziano Di Tomaso

  • Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells.

    Megan K. Levings;Silvia Gregori;Eleonora Tresoldi;Sabrina Cazzaniga

  • A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR.

    Hiroki Torikai;Andreas Reik;Pei Qi Liu;Yuanyue Zhou

  • Loss of Mismatched HLA in Leukemia after Stem-Cell Transplantation

    Luca Vago;Serena Kimi Perna;Monica Zanussi;Benedetta Mazzi

  • Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer

    Elena Provasi;Pietro Genovese;Angelo Lombardo;Zulma Magnani

  • T memory stem cells in health and disease

    Luca Gattinoni;Daniel E Speiser;Mathias Lichterfeld;Chiara Bonini

  • Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually

    Jakob Passweg;H. Baldomero;P. Bader;Chiara Bonini

  • Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I–II study

    Fabio Ciceri;Chiara Bonini;Maria Teresa Lupo Stanghellini;Attilio Bondanza

  • Use of haploidentical stem cell transplantation continues to increase: the 2015 European Society for Blood and Marrow Transplant activity survey report

    J R Passweg;H Baldomero;P Bader;C Bonini

  • Enhancing anti-tumour efficacy with immunotherapy combinations

    Funda Meric-Bernstam;James Larkin;Josep Tabernero;Chiara Bonini

  • Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation

    Cristina Toffalori;Laura Zito;Valentina Gambacorta;Michela Riba

  • Site-specific integration and tailoring of cassette design for sustainable gene transfer.

    Angelo Lombardo;Daniela Cesana;Pietro Genovese;Bruno Di Stefano

  • CD44v6-targeted T cells mediate potent antitumor effects against acute myeloid leukemia and multiple myeloma

    Monica Casucci;Benedetta Nicolis di Robilant;Laura Falcone;Barbara Camisa

  • Death after hematopoietic stem cell transplantation: changes over calendar year time, infections and associated factors.

    Jan Styczyński;Gloria Tridello;Linda Koster;Simona Iacobelli

  • Indications for haematopoietic stem cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2019

    Rafael F. Duarte;Myriam Labopin;Peter Bader;Grzegorz W. Basak

  • The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies.

    Catia Traversari;Sarah Marktel;Zulma Magnani;Patrizia Mangia

  • Peripheral Blood Lymphocytes as Target Cells of Retroviral Vector-Mediated Gene Transfer

    Fulvio Mavilio;Giuliana Ferrari;Silvano Rossini;Nadia Nobili

  • ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially

    Chiara Vantaggiato;Ivan Formentini;Attilio Bondanza;Chiara Bonini

Frequent Co-Authors

Fabio Ciceri
Fabio Ciceri Vita-Salute San Raffaele University
Claudio Bordignon
Claudio Bordignon MolMed (Italy)
Luca Vago
Luca Vago Vita-Salute San Raffaele University
Catia Traversari
Catia Traversari MolMed (Italy)
Luigi Naldini
Luigi Naldini Vita-Salute San Raffaele University
Arnon Nagler
Arnon Nagler Sheba Medical Center
Maurilio Ponzoni
Maurilio Ponzoni Vita-Salute San Raffaele University
Fulvio Mavilio
Fulvio Mavilio University of Modena and Reggio Emilia
Michael C. Holmes
Michael C. Holmes Ambys Medicines
Alessandro Aiuti
Alessandro Aiuti Vita-Salute San Raffaele University

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