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Immunology

D-Index
115
Citations
91804
World Ranking
387
National Ranking
15

Molecular Biology

D-Index
110
Citations
83943
World Ranking
364
National Ranking
12

Medicine

D-Index
115
Citations
91788
World Ranking
4422
National Ranking
165

Research.com Recognitions

  • 2017 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Ton N. M. Schumacher is affiliated with the Antoni van Leeuwenhoek Hospital in the Netherlands. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a significant focus on Oncology and Immunology as subfields. The scientific work conducted by Schumacher involves several topics, including cancer immunotherapy and biomarkers, immunotherapy and immune responses, CAR-T cell therapy research, immune cell function and interaction, T-cell and B-cell immunology, immune cells in cancer, and vaccines and immunoinformatics approaches.

Schumacher's recent publications include:

  • "B cells and tertiary lymphoid structures promote immunotherapy response," 2020, Nature
  • "CD8+ T cell states in human cancer: insights from single-cell analysis," 2020, Nature reviews. Cancer
  • "Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers," 2020, Nature Medicine
  • "Tertiary lymphoid structures in cancer," 2022, Science
  • "The CD47-SIRPα Immune Checkpoint," 2020, Immunity

The venues where Schumacher frequently publishes their work include bioRxiv (Cold Spring Harbor Laboratory), Annals of Oncology, Nature Medicine, Cancer Research, and Regular and Young Investigator Award Abstracts.

Among frequent co-authors associated with Schumacher are:

  • John B.A.G. Haanen
  • Christian U. Blank
  • Mireille Toebes
  • Daniela S. Thommen
  • Pia Kvistborg

Schumacher's contributions have been recognized through membership in the Academia Europaea, awarded in 2017.

Best Publications

  • Signatures of mutational processes in human cancer

    Ludmil B. Alexandrov;Serena Nik-Zainal;Serena Nik-Zainal;David C. Wedge;Samuel A. J. R. Aparicio

  • Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer

    Naiyer A. Rizvi;Naiyer A. Rizvi;Matthew D. Hellmann;Matthew D. Hellmann;Alexandra Snyder;Alexandra Snyder;Pia Kvistborg

  • Neoantigens in cancer immunotherapy

    Ton N. Schumacher;Robert D. Schreiber

  • Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma

    Jesse M. Zaretsky;Angel Garcia-Diaz;Daniel S. Shin;Helena Escuin-Ordinas

  • B cells and tertiary lymphoid structures promote immunotherapy response

    Beth A. Helmink;Sangeetha M. Reddy;Jianjun Gao;Shaojun Zhang

  • Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

    Matthew M. Gubin;Xiuli Zhang;Heiko Schuster;Etienne Caron

  • Regulation and Function of the PD-L1 Checkpoint

    Chong Sun;Riccardo Mezzadra;Ton N. Schumacher

  • The Human Cell Atlas

    Aviv Regev;Aviv Regev;Aviv Regev;Sarah A Teichmann;Sarah A Teichmann;Sarah A Teichmann;Eric S Lander;Eric S Lander;Eric S Lander;Ido Amit

  • Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses.

    R. P.M. Sutmuller;L. M. Van Duivenvoorde;A. Van Elsas;T. N.M. Schumacher

  • Defining ‘T cell exhaustion’

    Christian U Blank;W Nicholas Haining;Werner Held;Patrick G Hogan;Patrick G Hogan

  • CD8+ T cell states in human cancer: insights from single-cell analysis

    Anne M. van der Leun;Daniela S. Thommen;Ton N. Schumacher

  • Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers.

    Myriam Chalabi;Lorenzo F Fanchi;Krijn K Dijkstra;José G Van den Berg

  • T Cell Dysfunction in Cancer.

    Daniela S. Thommen;Ton N. Schumacher

  • Empty MHC class I molecules come out in the cold

    H G Ljunggren;N J Stam;C Ohlén;J J Neefjes

  • A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade

    Daniela S. Thommen;Daniela S. Thommen;Viktor H. Koelzer;Petra Herzig;Andreas Roller

  • Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma

    Hanjie Li;Anne M. van der Leun;Ido Yofe;Yaniv Lubling

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Mübeccel Akdis

  • Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids

    Krijn K Dijkstra;Chiara M Cattaneo;Fleur Weeber;Myriam Chalabi

  • CD27 is required for generation and long-term maintenance of T cell immunity

    J Hendriks;L A Gravestein;K Tesselaar;R A van Lier

  • Tertiary lymphoid structures in cancer

    Unknown

  • Tumor Exome Analysis Reveals Neoantigen-Specific T-Cell Reactivity in an Ipilimumab-Responsive Melanoma

    Nienke van Rooij;Marit M. van Buuren;Daisy Philips;Arno Velds

Frequent Co-Authors

John B. A. G. Haanen
John B. A. G. Haanen Antoni van Leeuwenhoek Hospital
Christian U. Blank
Christian U. Blank Antoni van Leeuwenhoek Hospital
Sine Reker Hadrup
Sine Reker Hadrup Technical University of Denmark
Hidde L. Ploegh
Hidde L. Ploegh Boston Children's Hospital
Annegien Broeks
Annegien Broeks Antoni van Leeuwenhoek Hospital
Lodewyk F. A. Wessels
Lodewyk F. A. Wessels Antoni van Leeuwenhoek Hospital
Nir Hacohen
Nir Hacohen Harvard University
Hergen Spits
Hergen Spits University of Amsterdam
Michael R. Stratton
Michael R. Stratton Wellcome Sanger Institute
Daniel S. Peeper
Daniel S. Peeper Antoni van Leeuwenhoek Hospital

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