World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
31188
World Ranking
8442
National Ranking
222

Research.com Recognitions

  • 2016 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Daniel S. Peeper is affiliated with the Antoni van Leeuwenhoek Hospital in the Netherlands and has a research focus that spans medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. Their work concentrates heavily on oncology, molecular biology, immunology, cancer research, and pulmonary and respiratory medicine. This multidisciplinary approach is reflected in numerous publications and collaborations.

The scientist's research covers key topics such as cancer immunotherapy and biomarkers, CAR-T cell therapy research, immunotherapy and immune responses, immune cell function and interaction, immune cells in cancer, RNA modifications and cancer, and melanoma and MAPK pathways.

Their publication record includes articles in high-impact journals such as Nature, Nature Communications, Nature Medicine, Science, Molecular Cell, and bioRxiv. Some of the notable recent papers authored or co-authored by Daniel S. Peeper include:

  • B cells and tertiary lymphoid structures promote immunotherapy response (2020, Nature)
  • The human tumor microbiome is composed of tumor type-specific intracellular bacteria (2020, Science)
  • Survival and biomarker analyses from the OpACIN-neo and OpACIN neoadjuvant immunotherapy trials in stage III melanoma (2021, Nature Medicine)
  • Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma (2021, Nature Communications)
  • Rational Cancer Treatment Combinations: An Urgent Clinical Need (2020, Molecular Cell)

Daniel S. Peeper collaborates frequently with a group of co-authors that includes Oscar Krijgsman, David W. Vredevoogd, Maarten Altelaar, Christian U. Blank, and Maarten A. Ligtenberg. These partnerships have contributed to a range of publications that reinforce their research presence across various subfields and topics.

Frequent publication venues where their work appears include bioRxiv (Cold Spring Harbor Laboratory), Nature, Nature Communications, Journal for ImmunoTherapy of Cancer, and Cancer Research, indicating a consistent output in both preprint and peer-reviewed literature.

Throughout their career, Daniel S. Peeper has been involved extensively in oncology-related research, with a special emphasis on cancer immunotherapy and biomarkers. Their work often intersects molecular biology and immunology aspects pertinent to cancer progression and therapy.

Awards recognizing their contributions include membership in the Academia Europaea since 2016 and membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • BRAFE600-associated senescence-like cell cycle arrest of human naevi

    Chrysiis Michaloglou;Liesbeth C. W. Vredeveld;Maria S. Soengas;Christophe Denoyelle

  • B cells and tertiary lymphoid structures promote immunotherapy response

    Beth A. Helmink;Sangeetha M. Reddy;Jianjun Gao;Shaojun Zhang

  • The essence of senescence

    Thomas Kuilman;Chrysiis Michaloglou;Wolter J. Mooi;Daniel S. Peeper

  • Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network

    Thomas Kuilman;Chrysiis Michaloglou;Liesbeth C.W. Vredeveld;Sirith Douma

  • The human tumor microbiome is composed of tumor type–specific intracellular bacteria

    Deborah Nejman;Ilana Livyatan;Garold Fuks;Nancy Gavert

  • Senescence-messaging secretome: SMS-ing cellular stress

    Thomas Kuilman;Daniel S. Peeper

  • Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB

    Sirith Douma;Theo van Laar;John Zevenhoven;Ralph Meuwissen

  • The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene

    Benjamin D. Rowland;René Bernards;Daniel S. Peeper

  • Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma

    Christian U. Blank;Elisa A. Rozeman;Lorenzo F. Fanchi;Karolina Sikorska

  • A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence

    Joanna Kaplon;Liang Zheng;Katrin Meissl;Barbara Chaneton

  • KLF4, p21 and context-dependent opposing forces in cancer.

    Benjamin D. Rowland;Daniel S. Peeper

  • Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma.

    Judith Müller;Oscar Krijgsman;Jennifer Tsoi;Lidia Robert

  • Interrogating open issues in cancer precision medicine with patient-derived xenografts

    Annette T. Byrne;Denis G. Alférez;Frédéric Amant;Daniela Annibali

  • Cell cycle-specific association of E2F with the p130 E1A-binding protein.

    D Cobrinik;P Whyte;D S Peeper;T Jacks

  • Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

    Daniel S. Peeper;Daniel S. Peeper;Todd M. Upton;Mohamed H. Ladha;Elizabeth Neuman

  • Oncogene-induced cell senescence--halting on the road to cancer.

    W J Mooi;D S Peeper

  • Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2, randomised, controlled trial.

    Elisa A Rozeman;Alexander M Menzies;Alexander C J van Akkooi;Chandra Adhikari

  • Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases

    Fleur Weeber;Marc van de Wetering;Marlous Hoogstraat;Krijn K Dijkstra

  • The kinesin KIF1Bβ acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor

    Susanne Schlisio;Rajappa S. Kenchappa;Liesbeth C.W. Vredeveld;Rani E. George

  • Cellular senescence in vivo: a barrier to tumorigenesis.

    Alexandre Prieur;Daniel S Peeper

Frequent Co-Authors

Christian U. Blank
Christian U. Blank Antoni van Leeuwenhoek Hospital
Lodewyk F. A. Wessels
Lodewyk F. A. Wessels Antoni van Leeuwenhoek Hospital
Ton N. M. Schumacher
Ton N. M. Schumacher Antoni van Leeuwenhoek Hospital
David J. Adams
David J. Adams Wellcome Sanger Institute
René Bernards
René Bernards Antoni van Leeuwenhoek Hospital
Ultan McDermott
Ultan McDermott AstraZeneca (United Kingdom)
John B. A. G. Haanen
John B. A. G. Haanen Antoni van Leeuwenhoek Hospital
Emile E. Voest
Emile E. Voest Antoni van Leeuwenhoek Hospital
Jos Jonkers
Jos Jonkers Antoni van Leeuwenhoek Hospital
Annegien Broeks
Annegien Broeks Antoni van Leeuwenhoek Hospital

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