World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
12787
World Ranking
10323
National Ranking
282

Overview

Helen Rizos is affiliated with Macquarie University in Australia, focusing on research primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several subfields, including Molecular Biology, Oncology, Immunology, Cancer Research, and Ophthalmology.

The scientist's research topics cover a range of areas related to cancer and immunotherapy. Key topics include:

  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Cancer Genomics and Diagnostics
  • Melanoma and MAPK Pathways
  • CAR-T Cell Therapy Research
  • Cutaneous Melanoma Detection and Management
  • Protein Degradation and Inhibitors

Helen Rizos has contributed to several publications in high-impact venues. Frequent publication venues include:

  • Journal of Clinical Oncology
  • Cancer Cell
  • Clinical Cancer Research
  • Annals of Oncology
  • Cancers

Selected recent papers provide insight into the focus of their research:

  • Transcriptional downregulation of MHC class I and melanoma de-differentiation in resistance to PD-1 inhibition, 2020, Nature Communications
  • Charge Conversional Biomimetic Nanocomplexes as a Multifunctional Platform for Boosting Orthotopic Glioblastoma RNAi Therapy, 2020, Nano Letters
  • Multiomic profiling of checkpoint inhibitor-treated melanoma: Identifying predictors of response and resistance, and markers of biological discordance, 2021, Cancer Cell
  • Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma, 2021, Cancer Cell
  • Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours, 2020, Nature Communications

Frequent co-authors collaborating on these works include:

  • Georgina V. Long
  • Richard A. Scolyer
  • Alexander M. Menzies
  • Jenny Lee
  • Matteo S. Carlino

Helen Rizos's research integrates molecular and clinical approaches to studying melanoma and other cancers, with an emphasis on mechanisms of resistance to therapies, immunological biomarkers, and genetic profiling. Their contributions extend across multiple study areas essential to advancing understanding of cancer biology and treatment responses.

Best Publications

  • Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy

    Tuba N. Gide;Camelia Quek;Alexander M. Menzies;Annie T. Tasker

  • BRAF inhibitor resistance mechanisms in metastatic melanoma; spectrum and clinical impact.

    Helen Rizos;Alexander M. Menzies;Gulietta M. Pupo;Matteo S. Carlino

  • Increased MAPK reactivation in early resistance to dabrafenib/trametinib combination therapy of BRAF-mutant metastatic melanoma

    Georgina V. Long;Carina Fung;Alexander M. Menzies;Gulietta M. Pupo

  • Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma.

    Elin S. Gray;Helen Rizos;Anna L. Reid;Suzanah C. Boyd

  • Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms.

    Douglas B. Johnson;Alexander M. Menzies;Lisa Zimmer;Zeynep Eroglu

  • Circulating Cytokines Predict Immune-Related Toxicity in Melanoma Patients Receiving Anti-PD-1-Based Immunotherapy.

    Su Yin Lim;Su Yin Lim;Jenny H. Lee;Jenny H. Lee;Tuba Nur Gide;Alexander M. Menzies;Alexander M. Menzies

  • Circulating tumour DNA predicts response to anti-PD1 antibodies in metastatic melanoma.

    J.H. Lee;J.H. Lee;J.H. Lee;G.V. Long;S. Boyd;S. Lo

  • Response of BRAF-Mutant Melanoma to BRAF Inhibition Is Mediated by a Network of Transcriptional Regulators of Glycolysis

    Tiffany J. Parmenter;Margarete Kleinschmidt;Kathryn M. Kinross;Simon T. Bond

  • Association Between Circulating Tumor DNA and Pseudoprogression in Patients With Metastatic Melanoma Treated With Anti-Programmed Cell Death 1 Antibodies.

    Jenny H. Lee;Jenny H. Lee;Georgina V. Long;Georgina V. Long;Alexander M. Menzies;Alexander M. Menzies;Serigne Lo

  • Transcriptional downregulation of MHC class I and melanoma de- differentiation in resistance to PD-1 inhibition.

    Jenny H. Lee;Elena Shklovskaya;Su Yin Lim;Matteo S. Carlino

  • Inducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-κB.

    Kavitha Gowrishankar;Dilini Gunatilake;Stuart J. Gallagher;Jessamy Tiffen

  • Neoadjuvant systemic therapy in melanoma: recommendations of the International Neoadjuvant Melanoma Consortium

    Rodabe N. Amaria;Alexander M. Menzies;Alexander M. Menzies;Alexander M. Menzies;Elizabeth M. Burton;Richard A. Scolyer;Richard A. Scolyer

  • A melanoma-associated germline mutation in exon 1β inactivates p14ARF

    Helen Rizos;Susana Puig;Cèlia Badenas;Josep Malvehy

  • Resistance to combination BRAF and MEK inhibition in metastatic melanoma: Where to next?

    Sarah J. Welsh;Helen Rizos;Richard A. Scolyer;Georgina V. Long

  • WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors

    Jamie N. Anastas;Rima M. Kulikauskas;Tigist Tamir;Helen Rizos

  • Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma

    Y. N.Vashisht Gopal;Helen Rizos;Guo Chen;Wanleng Deng

  • Cancer Surveillance in Gorlin Syndrome and Rhabdoid Tumor Predisposition Syndrome.

    William D. Foulkes;Junne Kamihara;D. Gareth R. Evans;Laurence Brugières

  • Neoadjuvant dabrafenib combined with trametinib for resectable, stage IIIB-C, BRAFV600 mutation-positive melanoma (NeoCombi): a single-arm, open-label, single-centre, phase 2 trial.

    Georgina V Long;Georgina V Long;Robyn P M Saw;Robyn P M Saw;Serigne Lo;Omgo E Nieweg;Omgo E Nieweg

  • Mutations in the INK4a/ARF Melanoma Susceptibility Locus Functionally Impair p14ARF

    Helen Rizos;Artur P. Darmanian;Elizabeth A. Holland;Graham J. Mann

  • Differentiation of cucumber mosaic virus isolates using the polymerase chain reaction.

    Helen Rizos;Linda V. Gunn;Ray D. Pares;Michael R. Gillings

Frequent Co-Authors

Richard F. Kefford
Richard F. Kefford Macquarie University
Richard A. Scolyer
Richard A. Scolyer Royal Prince Alfred Hospital
Georgina V. Long
Georgina V. Long University of Sydney
Alexander M. Menzies
Alexander M. Menzies University of Sydney
Matteo S. Carlino
Matteo S. Carlino University of Sydney
John F. Thompson
John F. Thompson University of Sydney
Graham J. Mann
Graham J. Mann Australian National University
James S. Wilmott
James S. Wilmott University of Sydney
Peter Hersey
Peter Hersey University of Sydney
Grant A. McArthur
Grant A. McArthur Peter MacCallum Cancer Centre

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Expanding your expertise beyond Biology and Biochemistry can open doors to diverse careers in healthcare and science. Many students explore related online degrees to increase employment prospects and skillsets. For example, Health Information Management is a growing field, and students can find affordable online HIM programs to build a career focused on medical data, records, and compliance.

If you’re interested in working alongside clinicians but not directly with patients, consider the administrative path. Find out is medical billing and coding in demand to learn more about stability and growth in medical office roles.

Students passionate about nutrition science can pursue a specialty with a nutrition masters online, preparing for roles in dietetics, research, or wellness consulting.

Those drawn to technology and patient care may be interested in diagnostic imaging. Accredited sonography programs online provide pathways to become an ultrasound technician — a highly respected allied health profession.

Exploring these related online programs can help you craft a unique educational journey and pursue the healthcare career that best matches your strengths and goals.

Best Scientists Citing Helen Rizos

Trending Scientists

Recently Published Articles