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Biology and Biochemistry

D-Index
76
Citations
31958
World Ranking
4938
National Ranking
118

Overview

Annegien Broeks is a researcher affiliated with Antoni van Leeuwenhoek Hospital in the Netherlands. Their work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focused contribution to Oncology, Surgery, Cancer Research, Molecular Biology, and Genetics. The scientist's research output reflects an emphasis on cancer-related studies, particularly in immunotherapy, biomarkers, and surgical approaches.

Areas of research predominantly covered include:

  • Cancer Immunotherapy and Biomarkers
  • Bladder and Urothelial Cancer Treatments
  • Immunotherapy and Immune Responses
  • CAR-T Cell Therapy Research
  • Cancer Genomics and Diagnostics
  • Breast Cancer Treatment Studies
  • BRCA Gene Mutations in Cancer

The scientist has contributed to multiple articles in high-profile journals. Frequent publication venues include:

  • Journal of Clinical Oncology
  • Nature Medicine
  • Cancer Research
  • Annals of Oncology
  • Clinical Cancer Research

Notable recent papers with their publication year and venues are:

  • "Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers," 2020, Nature Medicine
  • "Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses," 2020, Nature Genetics
  • "Preoperative ipilimumab plus nivolumab in locoregionally advanced urothelial cancer: the NABUCCO trial," 2020, Nature Medicine
  • "An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancer," 2021, Nature Medicine
  • "Survival and biomarker analyses from the OpACIN-neo and OpACIN neoadjuvant immunotherapy trials in stage III melanoma," 2021, Nature Medicine

Collaborations feature several frequent co-authors, including:

  • Christian U. Blank
  • Lodewyk F.A. Wessels
  • Erik Hooijberg
  • Dennis Peters
  • Petros Dimitriadis

Best Publications

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Landscape of somatic mutations in 560 breast cancer whole-genome sequences

    Serena Nik-Zainal;Serena Nik-Zainal;Helen Davies;Johan Staaf;Manasa Ramakrishna

  • The landscape of cancer genes and mutational processes in breast cancer

    Philip J. Stephens;Patrick S. Tarpey;Helen Davies;Peter Van Loo;Peter Van Loo

  • Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies

    Fiona M. Blows;Kristy E. Driver;Marjanka K. Schmidt;Annegien Broeks

  • Association analysis identifies 65 new breast cancer risk loci

    Kyriaki Michailidou;Kyriaki Michailidou;Sara Lindström;Sara Lindström;Joe Dennis;Jonathan Beesley

  • Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers.

    Myriam Chalabi;Lorenzo F Fanchi;Krijn K Dijkstra;José G Van den Berg

  • Large-scale genotyping identifies 41 new loci associated with breast cancer risk

    Kyriaki Michailidou;Per Hall;Anna Gonzalez-Neira;Maya Ghoussaini

  • Associations of Breast Cancer Risk Factors With Tumor Subtypes: A Pooled Analysis From the Breast Cancer Association Consortium Studies

    Xiaohong R. Yang;Jenny Chang-Claude;Ellen L. Goode;Fergus J. Couch

  • Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma

    Christian U. Blank;Elisa A. Rozeman;Lorenzo F. Fanchi;Karolina Sikorska

  • A common coding variant in CASP8 is associated with breast cancer risk

    Angela Cox;Alison M. Dunning;Montserrat Garcia-Closas;Sabapathy Balasubramanian

  • Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

    Kyriaki Michailidou;Jonathan Beesley;Sara Lindstrom;Sander Canisius

  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Stig E. Bojesen;Stig E. Bojesen;Karen A. Pooley;Sharon E. Johnatty;Jonathan Beesley

  • Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

    Nasim Mavaddat;Paul D.P. Pharoah;Kyriaki Michailidou;Jonathan Tyrer

  • MicroRNA related polymorphisms and breast cancer risk

    Sofia Khan;Dario Greco;Dario Greco;Kyriaki Michailidou;Roger L. Milne;Roger L. Milne

  • Identification of CMTM6 and CMTM4 as PD-L1 protein regulators

    Riccardo Mezzadra;Chong Sun;Lucas T. Jae;Raquel Gomez-Eerland

  • Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

    Shahana Ahmed;Gilles Thomas;Maya Ghoussaini;Catherine S. Healey

  • Genome-wide association studies identify four ER negative-specific breast cancer risk loci

    Montserrat Garcia-Closas;Fergus J. Couch;Sara Lindstrom;Kyriaki Michailidou

  • Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2, randomised, controlled trial.

    Elisa A Rozeman;Alexander M Menzies;Alexander C J van Akkooi;Chandra Adhikari

  • Roles of Radiation Dose, Chemotherapy, and Hormonal Factors in Breast Cancer Following Hodgkin’s Disease

    Flora E. van Leeuwen;Willem J. Klokman;Marilyn Stovall;Ellen C. Dahler

  • Breast Cancer Risk in Female Survivors of Hodgkin's Lymphoma: Lower Risk After Smaller Radiation Volumes

    Marie L. De Bruin;Judith Sparidans;Mars B. van't Veer;Evert M. Noordijk

Frequent Co-Authors

Graham G. Giles
Graham G. Giles University of Melbourne
Hiltrud Brauch
Hiltrud Brauch German Cancer Research Center
Roger L. Milne
Roger L. Milne Cancer Council Victoria
Marjanka K. Schmidt
Marjanka K. Schmidt Antoni van Leeuwenhoek Hospital
Peter A. Fasching
Peter A. Fasching University of Erlangen-Nuremberg
Barbara Burwinkel
Barbara Burwinkel Heidelberg University
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Douglas F. Easton
Douglas F. Easton University of Cambridge
Stig E. Bojesen
Stig E. Bojesen University of Copenhagen
Irene L. Andrulis
Irene L. Andrulis University of Toronto

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