Santina Bruzzone

Overview

Best Publications

• Connexin 43 hemichannels mediate Ca2+-regulated transmembrane NAD+ fluxes in intact cells

  Santina Bruzzone;Lucrezia Guida;Elena Zocchi;Luisa Franco

  579
  Citations

• A CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes.

  Alberto L Horenstein;Antonella Chillemi;Gianluca Zaccarello;Santina Bruzzone

  327
  Citations

• Abscisic acid is an endogenous cytokine in human granulocytes with cyclic ADP-ribose as second messenger

  Santina Bruzzone;Iliana Moreschi;Cesare Usai;Lucrezia Guida

  253
  Citations

• Autocrine and Paracrine Calcium Signaling by the CD38/NAD+/Cyclic ADP‐Ribose System

  Antonio De Flora;Elena Zocchi;Lucrezia Guida;Luisa Franco

  240
  Citations

• Slc12a8 is a nicotinamide mononucleotide transporter

  Alessia Grozio;Kathryn F. Mills;Jun Yoshino;Santina Bruzzone

  230
  Citations

• Catastrophic NAD + Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE

  Santina Bruzzone;Floriana Fruscione;Sara Morando;Tiziana Ferrando

  209
  Citations

• Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody.

  Karina Kaczmarek-Hajek;Jiong Zhang;Jiong Zhang;Robin Kopp;Antje Grosche;Antje Grosche

  199
  Citations

• Abscisic acid is an endogenous stimulator of insulin release from human pancreatic islets with cyclic ADP ribose as second messenger

  Santina Bruzzone;Nicoletta Bodrato;Cesare Usai;Lucrezia Guida

  194
  Citations

• The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses.

  Inga Bauer;Alessia Grozio;Denise Lasigliè;Giovanna Basile

  191
  Citations

• The transmembrane glycoprotein CD38 is a catalytically active transporter responsible for generation and influx of the second messenger cyclic ADP-ribose across membranes

  Luisa Franco;Lucrezia Guida;Santina Bruzzone;Elena Zocchi

  174
  Citations

• Evidence of a role for cyclic ADP‐ribose in calcium signalling and neurotransmitter release in cultured astrocytes

  Claudia Verderio;Santina Bruzzone;Elena Zocchi;Ernesto Fedele

  169
  Citations

• Extracellular NAD+ is an agonist of the human P2Y11 purinergic receptor in human granulocytes.

  Iliana Moreschi;Santina Bruzzone;Robert A. Nicholas;Floriana Fruscione

  166
  Citations

• Mesenchymal stem cells shape microglia effector functions through the release of CX3CL1.

  Debora Giunti;Benedetta Parodi;Cesare Usai;Laura Vergani

  166
  Citations

• The temperature-signaling cascade in sponges involves a heat-gated cation channel, abscisic acid, and cyclic ADP-ribose

  Elena Zocchi;Armando Carpaneto;Carlo Cerrano;Giorgio Bavestrello

  162
  Citations

• CD73 Protein as a Source of Extracellular Precursors for Sustained NAD+ Biosynthesis in FK866-treated Tumor Cells

  Alessia Grozio;Giovanna Sociali;Laura Sturla;Irene Caffa

  160
  Citations

• LANCL2 Is Necessary for Abscisic Acid Binding and Signaling in Human Granulocytes and in Rat Insulinoma Cells

  Laura Sturla;Chiara Fresia;Lucrezia Guida;Santina Bruzzone

  158
  Citations

• Expression of CD38 Increases Intracellular Calcium Concentration and Reduces Doubling Time in HeLa and 3T3 Cells

  Elena Zocchi;Antonio Daga;Cesare Usai;Luisa Franco

  156
  Citations

• A self-restricted CD38-connexin 43 cross-talk affects NAD+ and cyclic ADP-ribose metabolism and regulates intracellular calcium in 3T3 fibroblasts.

  Santina Bruzzone;Luisa Franco;Lucrezia Guida;Elena Zocchi

  147
  Citations

• Paracrine roles of NAD+ and cyclic ADP-ribose in increasing intracellular calcium and enhancing cell proliferation of 3T3 fibroblasts.

  Luisa Franco;Elena Zocchi;Cesare Usai;Lucrezia Guida

  142
  Citations

• Catastrophic NAD+ Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE.

  Santina Bruzzone;Floriana Fruscione;Sara Morando;Alessandro Poggi

  7
  Citations