Matthias U. Kassack mainly focuses on Receptor, Biochemistry, Stereochemistry, Suramin and Agonist. His Receptor research focuses on subjects like Calcium, which are linked to Nucleotide, Platelet activation and Platelet. His study connects Molecular biology and Biochemistry.
His Stereochemistry research incorporates themes from Conformational isomerism, Disiloxane and Aqueous solution. His Agonist research includes themes of Stimulation and G protein-coupled receptor. His studies examine the connections between Intracellular and genetics, as well as such issues in DNA repair, with regards to Cell culture.
His primary areas of investigation include Stereochemistry, Biochemistry, Receptor, Cell culture and Suramin. His studies in Stereochemistry integrate themes in fields like Endophytic fungus and Cytotoxicity. His study in Biochemistry concentrates on Agonist, Structure–activity relationship, Intracellular, In vitro and Potency.
His Receptor research incorporates themes from Xenopus and Pharmacology. His Cell culture study combines topics from a wide range of disciplines, such as Cytotoxic T cell, Apoptosis and Cancer research. Matthias U. Kassack is studying Suramin Sodium, which is a component of Suramin.
Matthias U. Kassack mainly investigates Cancer research, Histone deacetylase, Biochemistry, HDAC6 and Cell culture. His work deals with themes such as Caspase 3, Ovarian cancer and DNA damage, which intersect with Histone deacetylase. His Biochemistry research focuses on Bacillus subtilis and how it relates to Fermentation.
His work focuses on many connections between HDAC6 and other disciplines, such as Cytotoxicity, that overlap with his field of interest in Proteasome inhibitor, Plasma protein binding, Enzyme, Daunorubicin and Structure–activity relationship. His study looks at the intersection of Cell culture and topics like Clonostachys rosea with Stereochemistry. With his scientific publications, his incorporates both Stereochemistry and Coniella fragariae.
His main research concerns Histone deacetylase, Cancer research, Acetylation, Ovarian cancer and Caspase 3. Histone deacetylase is closely attributed to Cancer cell in his work. His research on Cancer cell often connects related areas such as Histone H3.
His work carried out in the field of Acetylation brings together such families of science as Regulation of gene expression, Histone, DNA and Cell biology. His study in Ovarian cancer is interdisciplinary in nature, drawing from both Panobinostat, Survivin, Downregulation and upregulation, Entinostat and HDAC6. His Caspase 3 research is multidisciplinary, incorporating perspectives in HDAC3, Cell culture and HDAC1.
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Comparison of the usefulness of the MTT, ATP, and calcein assays to predict the potency of cytotoxic agents in various human cancer cell lines.
Henrik Mueller;Matthias U. Kassack;Michael Wiese.
Journal of Biomolecular Screening (2004)
Common variants in P2RY11 are associated with narcolepsy
Birgitte R Kornum;Minae Kawashima;Minae Kawashima;Juliette Faraco;Ling Lin.
Nature Genetics (2011)
Structure–Activity Studies on Suramin Analogues as Inhibitors of NAD+‐Dependent Histone Deacetylases (Sirtuins)
Johannes Trapp;Rene Meier;Darunee Hongwiset;Matthias U. Kassack.
Hyperactivation of the Insulin-like Growth Factor Receptor I Signaling Pathway Is an Essential Event for Cisplatin Resistance of Ovarian Cancer Cells
Niels Eckstein;Kati Servan;Barbara Hildebrandt;Anne Pölitz.
Cancer Research (2009)
Histone Deacetylase (HDAC) Inhibitors with a Novel Connecting Unit Linker Region Reveal a Selectivity Profile for HDAC4 and HDAC5 with Improved Activity against Chemoresistant Cancer Cells
Linda Marek;Alexandra Hamacher;Finn K Hansen;Krystina Kuna.
Journal of Medicinal Chemistry (2013)
Extracellular NAD+ Is an Agonist of the Human P2Y11 Purinergic Receptor in Human Granulocytes
Iliana Moreschi;Santina Bruzzone;Robert A. Nicholas;Floriana Fruscione.
Journal of Biological Chemistry (2006)
Relevance of drug uptake and efflux for cisplatin sensitivity of tumor cells
Jochen Zisowsky;Susanne Koegel;Stefan Leyers;Krishna Devarakonda.
Biochemical Pharmacology (2007)
Structure-activity relationships of suramin and pyridoxal-5'-phosphate derivatives as P2 receptor antagonists.
Gunter Lambrecht;Kirsten Braun;Susanne Damer;Matthias Ganso.
Current Pharmaceutical Design (2002)
Discovery of Potent and Selective Agonists for the Free Fatty Acid Receptor 1 (FFA1/GPR40), a Potential Target for the Treatment of Type II Diabetes
Elisabeth Christiansen;Christian Urban;Nicole Merten;Kathrin Liebscher.
Journal of Medicinal Chemistry (2008)
Purinergic receptors influence the differentiation of human mesenchymal stem cells.
Nina Zippel;Christian Andreas Limbach;Nadine Ratajski;Christian Urban.
Stem Cells and Development (2012)
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