World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
8048
World Ranking
15300
National Ranking
1083

Matthias U. Kassack publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Matthias U. Kassack sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 166 publications — 34th percentile

34% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Matthias U. Kassack D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Matthias U. Kassack sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 55 D-Index — 25th percentile

25% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Matthias U. Kassack is affiliated with Heinrich Heine University Düsseldorf in Germany. Their research output spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine, with a notable focus on Molecular Biology and Oncology among subfields.

The main research topics in their work include:

  • Histone Deacetylase Inhibitors Research
  • Protein Degradation and Inhibitors
  • Peptidase Inhibition and Analysis
  • Epigenetics and DNA Methylation
  • CAR-T cell therapy research
  • Adenosine and Purinergic Signaling
  • Ubiquitin and proteasome pathways

The scientist has published multiple papers in various journals. Some of the recent works are:

  • Hydroxamic Acids Immobilized on Resins (HAIRs): Synthesis of Dual-Targeting HDAC Inhibitors and HDAC Degraders (PROTACs), 2020, Angewandte Chemie International Edition
  • Multicomponent Synthesis, Binding Mode, and Structure-Activity Relationship of Selective Histone Deacetylase 6 (HDAC6) Inhibitors with Bifurcated Capping Groups, 2020, Journal of Medicinal Chemistry
  • Combination of Decitabine and Entinostat Synergistically Inhibits Urothelial Bladder Cancer Cells via Activation of FoxO1, 2020, Cancers
  • The Novel Class IIa Selective Histone Deacetylase Inhibitor YAK540 Is Synergistic with Bortezomib in Leukemia Cell Lines, 2022, International Journal of Molecular Sciences
  • Priming with HDAC Inhibitors Sensitizes Ovarian Cancer Cells to Treatment with Cisplatin and HSP90 Inhibitors, 2020, International Journal of Molecular Sciences

The scientist frequently publishes in the following venues:

  • International Journal of Molecular Sciences
  • Journal of Medicinal Chemistry
  • European Journal of Medicinal Chemistry
  • Cancers
  • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Frequent collaborators include:

  • Alexandra Hamacher
  • Finn K. Hansen
  • Thomas Kurz
  • Arndt Borkhardt
  • Sanil Bhatia

Best Publications

  • Comparison of the usefulness of the MTT, ATP, and calcein assays to predict the potency of cytotoxic agents in various human cancer cell lines.

    Henrik Mueller;Matthias U. Kassack;Michael Wiese

  • Common variants in P2RY11 are associated with narcolepsy

    Birgitte R Kornum;Minae Kawashima;Minae Kawashima;Juliette Faraco;Ling Lin

  • Histone Deacetylase (HDAC) Inhibitors with a Novel Connecting Unit Linker Region Reveal a Selectivity Profile for HDAC4 and HDAC5 with Improved Activity against Chemoresistant Cancer Cells

    Linda Marek;Alexandra Hamacher;Finn K Hansen;Krystina Kuna

  • Structure–Activity Studies on Suramin Analogues as Inhibitors of NAD+-Dependent Histone Deacetylases (Sirtuins)

    Johannes Trapp;Rene Meier;Darunee Hongwiset;Matthias U. Kassack

  • Hyperactivation of the Insulin-like Growth Factor Receptor I Signaling Pathway Is an Essential Event for Cisplatin Resistance of Ovarian Cancer Cells

    Niels Eckstein;Kati Servan;Barbara Hildebrandt;Anne Pölitz

  • Relevance of drug uptake and efflux for cisplatin sensitivity of tumor cells

    Jochen Zisowsky;Susanne Koegel;Stefan Leyers;Krishna Devarakonda

  • Extracellular NAD+ is an agonist of the human P2Y11 purinergic receptor in human granulocytes.

    Iliana Moreschi;Santina Bruzzone;Robert A. Nicholas;Floriana Fruscione

  • Discovery of Potent and Selective Agonists for the Free Fatty Acid Receptor 1 (FFA1/GPR40), a Potential Target for the Treatment of Type II Diabetes

    Elisabeth Christiansen;Christian Urban;Nicole Merten;Kathrin Liebscher

  • Structure-activity relationships of suramin and pyridoxal-5'-phosphate derivatives as P2 receptor antagonists.

    Gunter Lambrecht;Kirsten Braun;Susanne Damer;Matthias Ganso

  • Purinergic receptors influence the differentiation of human mesenchymal stem cells.

    Nina Zippel;Christian Andreas Limbach;Nadine Ratajski;Christian Urban

  • Inhibition of neutrophil apoptosis by ATP is mediated by the P2Y11 receptor.

    Kathryn R. Vaughan;Leanne Stokes;Lynne R. Prince;Helen M. Marriott

  • Hetero-oligomerization of the P2Y11 receptor with the P2Y1 receptor controls the internalization and ligand selectivity of the P2Y11 receptor.

    Denise Ecke;Theodor Hanck;Mohan E. Tulapurkar;Rainer Schäfer

  • Sila-haloperidol: A Silicon Analogue of the Dopamine (D2) Receptor Antagonist Haloperidol§

    Reinhold Tacke;Tilman Heinrich;Rüdiger Bertermann;Christian Burschka

  • Epidermal Growth Factor Receptor Pathway Analysis Identifies Amphiregulin as a Key Factor for Cisplatin Resistance of Human Breast Cancer Cells

    Niels Eckstein;Kati Servan;Luc Girard;Di Cai

  • NF546 [4,4′-(Carbonylbis(imino-3,1-phenylene-carbonylimino-3,1-(4-methyl-phenylene)-carbonylimino))-bis(1,3-xylene-α,α′-diphosphonic Acid) Tetrasodium Salt] Is a Non-Nucleotide P2Y11 Agonist and Stimulates Release of Interleukin-8 from Human Monocyte-Derived Dendritic Cells

    Sabine Meis;Alexandra Hamacher;Darunee Hongwiset;Claudia Marzian

  • Pro-Apoptotic and Immunostimulatory Tetrahydroxanthone Dimers from the Endophytic Fungus Phomopsis longicolla

    David Rönsberg;Abdessamad Debbab;Attila Mándi;Vera Vasylyeva

  • Structure-activity relationships of analogues of NF449 confirm NF449 as the most potent and selective known P2X1 receptor antagonist.

    Matthias U Kassack;Kirsten Braun;Matthias Ganso;Heiko Ullmann

  • Synthesis and Structure−Activity Relationships of Suramin-Derived P2Y11 Receptor Antagonists with Nanomolar Potency

    Heiko Ullmann;Sabine Meis;Darunee Hongwiset;Claudia Marzian

  • Inhibition of Platelet Functions and Thrombosis through Selective or Nonselective Inhibition of the Platelet P2 Receptors with Increasing Doses of NF449 [4,4′,4″,4″′-(Carbonylbis(imino-5,1,3-benzenetriylbis-(carbonylimino)))tetrakis-benzene-1,3-disulfonic Acid Octasodium Salt]

    Béatrice Hechler;Stéphanie Magnenat;Maddalena L. Zighetti;Matthias U. Kassack

  • Functional screening of G protein-coupled receptors by measuring intracellular calcium with a fluorescence microplate reader.

    Matthias U. Kassack;Barbara Höfgen;Jochen Lehmann;Niels Eckstein

Frequent Co-Authors

Peter Proksch
Peter Proksch Heinrich Heine University Düsseldorf
Holger Gohlke
Holger Gohlke Heinrich Heine University Düsseldorf
Wenhan Lin
Wenhan Lin Peking University
Tibor Kurtán
Tibor Kurtán University of Debrecen
Trond Ulven
Trond Ulven University of Copenhagen
Michael Wiese
Michael Wiese University of Bonn
Günther Schmalzing
Günther Schmalzing RWTH Aachen University
Christoph Janiak
Christoph Janiak Heinrich Heine University Düsseldorf
Werner E. G. Müller
Werner E. G. Müller Johannes Gutenberg University of Mainz
Arndt Borkhardt
Arndt Borkhardt Heinrich Heine University Düsseldorf

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