Matthias U. Kassack

Overview

Best Publications

• Comparison of the usefulness of the MTT, ATP, and calcein assays to predict the potency of cytotoxic agents in various human cancer cell lines.

  Henrik Mueller;Matthias U. Kassack;Michael Wiese

  313
  Citations

• Common variants in P2RY11 are associated with narcolepsy

  Birgitte R Kornum;Minae Kawashima;Minae Kawashima;Juliette Faraco;Ling Lin

  265
  Citations

• Histone Deacetylase (HDAC) Inhibitors with a Novel Connecting Unit Linker Region Reveal a Selectivity Profile for HDAC4 and HDAC5 with Improved Activity against Chemoresistant Cancer Cells

  Linda Marek;Alexandra Hamacher;Finn K Hansen;Krystina Kuna

  243
  Citations

• Structure–Activity Studies on Suramin Analogues as Inhibitors of NAD+-Dependent Histone Deacetylases (Sirtuins)

  Johannes Trapp;Rene Meier;Darunee Hongwiset;Matthias U. Kassack

  235
  Citations

• Hyperactivation of the Insulin-like Growth Factor Receptor I Signaling Pathway Is an Essential Event for Cisplatin Resistance of Ovarian Cancer Cells

  Niels Eckstein;Kati Servan;Barbara Hildebrandt;Anne Pölitz

  222
  Citations

• Relevance of drug uptake and efflux for cisplatin sensitivity of tumor cells

  Jochen Zisowsky;Susanne Koegel;Stefan Leyers;Krishna Devarakonda

  171
  Citations

• Extracellular NAD+ is an agonist of the human P2Y11 purinergic receptor in human granulocytes.

  Iliana Moreschi;Santina Bruzzone;Robert A. Nicholas;Floriana Fruscione

  166
  Citations

• Discovery of Potent and Selective Agonists for the Free Fatty Acid Receptor 1 (FFA1/GPR40), a Potential Target for the Treatment of Type II Diabetes

  Elisabeth Christiansen;Christian Urban;Nicole Merten;Kathrin Liebscher

  148
  Citations

• Structure-activity relationships of suramin and pyridoxal-5'-phosphate derivatives as P2 receptor antagonists.

  Gunter Lambrecht;Kirsten Braun;Susanne Damer;Matthias Ganso

  144
  Citations

• Purinergic receptors influence the differentiation of human mesenchymal stem cells.

  Nina Zippel;Christian Andreas Limbach;Nadine Ratajski;Christian Urban

  140
  Citations

• Inhibition of neutrophil apoptosis by ATP is mediated by the P2Y11 receptor.

  Kathryn R. Vaughan;Leanne Stokes;Lynne R. Prince;Helen M. Marriott

  136
  Citations

• Hetero-oligomerization of the P2Y11 receptor with the P2Y1 receptor controls the internalization and ligand selectivity of the P2Y11 receptor.

  Denise Ecke;Theodor Hanck;Mohan E. Tulapurkar;Rainer Schäfer

  132
  Citations

• Sila-haloperidol: A Silicon Analogue of the Dopamine (D2) Receptor Antagonist Haloperidol§

  Reinhold Tacke;Tilman Heinrich;Rüdiger Bertermann;Christian Burschka

  126
  Citations

• Epidermal Growth Factor Receptor Pathway Analysis Identifies Amphiregulin as a Key Factor for Cisplatin Resistance of Human Breast Cancer Cells

  Niels Eckstein;Kati Servan;Luc Girard;Di Cai

  125
  Citations

• NF546 [4,4′-(Carbonylbis(imino-3,1-phenylene-carbonylimino-3,1-(4-methyl-phenylene)-carbonylimino))-bis(1,3-xylene-α,α′-diphosphonic Acid) Tetrasodium Salt] Is a Non-Nucleotide P2Y11 Agonist and Stimulates Release of Interleukin-8 from Human Monocyte-Derived Dendritic Cells

  Sabine Meis;Alexandra Hamacher;Darunee Hongwiset;Claudia Marzian

  124
  Citations

• Pro-Apoptotic and Immunostimulatory Tetrahydroxanthone Dimers from the Endophytic Fungus Phomopsis longicolla

  David Rönsberg;Abdessamad Debbab;Attila Mándi;Vera Vasylyeva

  120
  Citations

• Structure-activity relationships of analogues of NF449 confirm NF449 as the most potent and selective known P2X1 receptor antagonist.

  Matthias U Kassack;Kirsten Braun;Matthias Ganso;Heiko Ullmann

  116
  Citations

• Synthesis and Structure−Activity Relationships of Suramin-Derived P2Y11 Receptor Antagonists with Nanomolar Potency

  Heiko Ullmann;Sabine Meis;Darunee Hongwiset;Claudia Marzian

  116
  Citations

• Inhibition of Platelet Functions and Thrombosis through Selective or Nonselective Inhibition of the Platelet P2 Receptors with Increasing Doses of NF449 [4,4′,4″,4″′-(Carbonylbis(imino-5,1,3-benzenetriylbis-(carbonylimino)))tetrakis-benzene-1,3-disulfonic Acid Octasodium Salt]

  Béatrice Hechler;Stéphanie Magnenat;Maddalena L. Zighetti;Matthias U. Kassack

  112
  Citations

• Functional screening of G protein-coupled receptors by measuring intracellular calcium with a fluorescence microplate reader.

  Matthias U. Kassack;Barbara Höfgen;Jochen Lehmann;Niels Eckstein

  110
  Citations