Bernard A.J. Roelen mostly deals with Embryo, Cell biology, Molecular biology, Embryonic stem cell and Genetics. His Embryo research incorporates themes from Endometrium, Andrology and Immunology. His biological study spans a wide range of topics, including Regulation of gene expression, Bone morphogenetic protein and Cellular differentiation.
His work deals with themes such as Endocrinology, Internal medicine and Osteoblast, which intersect with Bone morphogenetic protein. His work carried out in the field of Molecular biology brings together such families of science as Reference genes, Non-coding RNA, Gene expression, Ectoderm and Nanog Homeobox Protein. His research integrates issues of Mesoderm, Bone morphogenetic protein 4, Signal transduction and Germ cell in his study of Epiblast.
His primary areas of investigation include Cell biology, Oocyte, Embryo, Andrology and Internal medicine. Bernard A.J. Roelen has researched Cell biology in several fields, including Anatomy and Somatic cell. His study with Embryo involves better knowledge in Genetics.
His research on Andrology also deals with topics like
His scientific interests lie mostly in Cell biology, Oocyte, Embryo, In vitro maturation and Andrology. The various areas that Bernard A.J. Roelen examines in his Cell biology study include Embryonic stem cell, Gene, Induced pluripotent stem cell, Transcriptome and Sperm. His Oocyte study combines topics in areas such as Gene expression, Apoptosis, Blastocyst, Piwi-interacting RNA and Mitochondrion.
His Blastocyst study introduces a deeper knowledge of Genetics. His study in Embryo is interdisciplinary in nature, drawing from both XIST and Totipotent. His Andrology research integrates issues from Embryo culture, Lipid metabolism, Germ cell and Beauvericin.
Bernard A.J. Roelen mainly investigates Oocyte, Andrology, Embryo, Cell biology and In vitro maturation. Bernard A.J. Roelen combines subjects such as Saturated fatty acid, Apoptosis and Blastocyst with his study of Oocyte. His Chromatoid body study, which is part of a larger body of work in Andrology, is frequently linked to Metabolome, bridging the gap between disciplines.
His studies deal with areas such as XIST and X-inactivation as well as Embryo. Specifically, his work in Cell biology is concerned with the study of Epiblast. His studies examine the connections between In vitro maturation and genetics, as well as such issues in In vitro fertilisation, with regards to Animal science, Follicular fluid, Embryo culture, Lactation and Follicular phase.
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Bmp4 is required for the generation of primordial germ cells in the mouse embryo.
K. A. Lawson;N. R. Dunn;B. A. J. Roelen;L. M. Zeinstra.
Genes & Development (1999)
Sclerostin Is an Osteocyte-expressed Negative Regulator of Bone Formation, But Not a Classical BMP Antagonist
Rutger L. van Bezooijen;Bernard A.J. Roelen;Annemieke Visser;Lianne van der Wee-Pals.
Journal of Experimental Medicine (2004)
Natural Selection of Human Embryos: Impaired Decidualization of Endometrium Disables Embryo-Maternal Interactions and Causes Recurrent Pregnancy Loss
Madhuri Salker;Gijs Teklenburg;Mariam Molokhia;Stuart Lavery.
PLOS ONE (2010)
Increased cardiomyocyte differentiation from human embryonic stem cells in serum-free cultures.
Robert Passier;Dorien Ward‐van Oostwaard;Jolanda Snapper;Jantine Kloots.
Stem Cells (2005)
Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition
Jan Willem Voncken;Bernard A. J. Roelen;Mieke Roefs;Stijn de Vries.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Natural Selection of Human Embryos: Decidualizing Endometrial Stromal Cells Serve as Sensors of Embryo Quality upon Implantation
Gijs Teklenburg;Madhuri S. Salker;Mariam Molokhia;Stuart Lavery.
PLOS ONE (2010)
DNA damage in bovine sperm does not block fertilization and early embryonic development but induces apoptosis after the first cleavages.
A N Fatehi;M M Bevers;E Schoevers;B A J Roelen.
Journal of Andrology (2006)
Oleic Acid Prevents Detrimental Effects of Saturated Fatty Acids on Bovine Oocyte Developmental Competence
Hilde Aardema;Peter L.A.M. Vos;Francesca Lolicato;Bernard A.J. Roelen.
Biology of Reproduction (2011)
Controlling mesenchymal stem cell differentiation by TGFΒ family members
Bernard A.J. Roelen;Peter ten Dijke.
Journal of Orthopaedic Science (2003)
The roles of FGF and MAP kinase signaling in the segregation of the epiblast and hypoblast cell lineages in bovine and human embryos
Ewart W. Kuijk;Leni T. A. van Tol;Hilde Van de Velde;Richard Wubbolts.
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