D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 46 Citations 10,166 146 World Ranking 15046 National Ranking 352

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Genetics
  • Cellular differentiation

Bernard A.J. Roelen mostly deals with Embryo, Cell biology, Molecular biology, Embryonic stem cell and Genetics. His Embryo research incorporates themes from Endometrium, Andrology and Immunology. His biological study spans a wide range of topics, including Regulation of gene expression, Bone morphogenetic protein and Cellular differentiation.

His work deals with themes such as Endocrinology, Internal medicine and Osteoblast, which intersect with Bone morphogenetic protein. His work carried out in the field of Molecular biology brings together such families of science as Reference genes, Non-coding RNA, Gene expression, Ectoderm and Nanog Homeobox Protein. His research integrates issues of Mesoderm, Bone morphogenetic protein 4, Signal transduction and Germ cell in his study of Epiblast.

His most cited work include:

  • BMP4 IS REQUIRED FOR THE GENERATION OF PRIMORDIAL GERM CELLS IN THE MOUSE EMBRYO (1060 citations)
  • Sclerostin Is an Osteocyte-expressed Negative Regulator of Bone Formation, But Not a Classical BMP Antagonist (726 citations)
  • Increased cardiomyocyte differentiation from human embryonic stem cells in serum-free cultures. (315 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Cell biology, Oocyte, Embryo, Andrology and Internal medicine. Bernard A.J. Roelen has researched Cell biology in several fields, including Anatomy and Somatic cell. His study with Embryo involves better knowledge in Genetics.

His research on Andrology also deals with topics like

  • Blastocyst that connect with fields like Embryo culture,
  • In vitro, which have a strong connection to In vivo. His Internal medicine study which covers Endocrinology that intersects with Folliculogenesis, Follicular fluid and Receptor. His Embryonic stem cell study incorporates themes from Molecular biology and Immunology.

He most often published in these fields:

  • Cell biology (40.00%)
  • Oocyte (30.67%)
  • Embryo (26.00%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (40.00%)
  • Oocyte (30.67%)
  • Embryo (26.00%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cell biology, Oocyte, Embryo, In vitro maturation and Andrology. The various areas that Bernard A.J. Roelen examines in his Cell biology study include Embryonic stem cell, Gene, Induced pluripotent stem cell, Transcriptome and Sperm. His Oocyte study combines topics in areas such as Gene expression, Apoptosis, Blastocyst, Piwi-interacting RNA and Mitochondrion.

His Blastocyst study introduces a deeper knowledge of Genetics. His study in Embryo is interdisciplinary in nature, drawing from both XIST and Totipotent. His Andrology research integrates issues from Embryo culture, Lipid metabolism, Germ cell and Beauvericin.

Between 2015 and 2021, his most popular works were:

  • Stearoyl-CoA desaturase activity in bovine cumulus cells protects the oocyte against saturated fatty acid stress. (31 citations)
  • Toxicity of beauvericin on porcine oocyte maturation and preimplantation embryo development. (19 citations)
  • Human-specific subcellular compartmentalization of P-element induced wimpy testis-like (PIWIL) granules during germ cell development and spermatogenesis (16 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Genetics
  • Cellular differentiation

Bernard A.J. Roelen mainly investigates Oocyte, Andrology, Embryo, Cell biology and In vitro maturation. Bernard A.J. Roelen combines subjects such as Saturated fatty acid, Apoptosis and Blastocyst with his study of Oocyte. His Chromatoid body study, which is part of a larger body of work in Andrology, is frequently linked to Metabolome, bridging the gap between disciplines.

His studies deal with areas such as XIST and X-inactivation as well as Embryo. Specifically, his work in Cell biology is concerned with the study of Epiblast. His studies examine the connections between In vitro maturation and genetics, as well as such issues in In vitro fertilisation, with regards to Animal science, Follicular fluid, Embryo culture, Lactation and Follicular phase.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Bmp4 is required for the generation of primordial germ cells in the mouse embryo.

K. A. Lawson;N. R. Dunn;B. A. J. Roelen;L. M. Zeinstra.
Genes & Development (1999)

1440 Citations

Sclerostin Is an Osteocyte-expressed Negative Regulator of Bone Formation, But Not a Classical BMP Antagonist

Rutger L. van Bezooijen;Bernard A.J. Roelen;Annemieke Visser;Lianne van der Wee-Pals.
Journal of Experimental Medicine (2004)

994 Citations

Natural Selection of Human Embryos: Impaired Decidualization of Endometrium Disables Embryo-Maternal Interactions and Causes Recurrent Pregnancy Loss

Madhuri Salker;Gijs Teklenburg;Mariam Molokhia;Stuart Lavery.
PLOS ONE (2010)

417 Citations

Increased cardiomyocyte differentiation from human embryonic stem cells in serum-free cultures.

Robert Passier;Dorien Ward‐van Oostwaard;Jolanda Snapper;Jantine Kloots.
Stem Cells (2005)

415 Citations

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition

Jan Willem Voncken;Bernard A. J. Roelen;Mieke Roefs;Stijn de Vries.
Proceedings of the National Academy of Sciences of the United States of America (2003)

375 Citations

Natural Selection of Human Embryos: Decidualizing Endometrial Stromal Cells Serve as Sensors of Embryo Quality upon Implantation

Gijs Teklenburg;Madhuri S. Salker;Mariam Molokhia;Stuart Lavery.
PLOS ONE (2010)

323 Citations

DNA damage in bovine sperm does not block fertilization and early embryonic development but induces apoptosis after the first cleavages.

A N Fatehi;M M Bevers;E Schoevers;B A J Roelen.
Journal of Andrology (2006)

303 Citations

Oleic Acid Prevents Detrimental Effects of Saturated Fatty Acids on Bovine Oocyte Developmental Competence

Hilde Aardema;Peter L.A.M. Vos;Francesca Lolicato;Bernard A.J. Roelen.
Biology of Reproduction (2011)

270 Citations

Controlling mesenchymal stem cell differentiation by TGFΒ family members

Bernard A.J. Roelen;Peter ten Dijke.
Journal of Orthopaedic Science (2003)

265 Citations

The roles of FGF and MAP kinase signaling in the segregation of the epiblast and hypoblast cell lineages in bovine and human embryos

Ewart W. Kuijk;Leni T. A. van Tol;Hilde Van de Velde;Richard Wubbolts.
Development (2012)

236 Citations

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