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Biology and Biochemistry

D-Index
58
Citations
9849
World Ranking
13395
National Ranking
334

Overview

Bart M. Gadella is affiliated with Utrecht University in the Netherlands. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on reproductive health, molecular mechanisms, and cellular biology.

Their work covers a range of subfields including Reproductive Medicine, Molecular Biology, Public Health, Environmental and Occupational Health, Genetics, and Surgery. Within these areas, the main topics addressed include:

  • Sperm and Testicular Function
  • Reproductive Biology and Fertility
  • Genetic and Kidney Cyst Diseases
  • Plant Reproductive Biology
  • Extracellular vesicles in disease
  • Advanced Electron Microscopy Techniques and Applications
  • Photosynthetic Processes and Mechanisms

Recent publications illustrate the breadth of Gadella's scientific contributions. Selected papers include:

  • The multi-scale architecture of mammalian sperm flagella and implications for ciliary motility (2021), published in The EMBO Journal
  • Quantitative Proteomic Analysis of Seminal Plasma, Sperm Membrane Proteins, and Seminal Extracellular Vesicles Suggests Vesicular Mechanisms Aid in the Removal and Addition of Proteins to the Ram Sperm Membrane (2020), published in PROTEOMICS
  • Hatching is modulated by microRNA-378a-3p derived from extracellular vesicles secreted by blastocysts (2022), published in Proceedings of the National Academy of Sciences
  • Safeguarding Female Reproductive Health Against Endocrine Disrupting Chemicals-The FREIA Project (2020), published in International Journal of Molecular Sciences
  • In-cell structures of conserved supramolecular protein arrays at the mitochondria-cytoskeleton interface in mammalian sperm (2021), published in Proceedings of the National Academy of Sciences

The frequent co-authors with whom Gadella has collaborated include Elizabeth G. Bromfield, J. Bernd Helms, Miguel Ricardo Leung, Min Zhang, and Tzviya Zeev-Ben-Mordehai.

The most common publication venues for Gadella's work are:

  • Biology of Reproduction
  • Frontiers in Cell and Developmental Biology
  • Animal Reproduction Science
  • Proceedings of the National Academy of Sciences
  • International Journal of Molecular Sciences

Best Publications

  • Detection of damage in mammalian sperm cells.

    P.F.N. Silva;B.M. Gadella

  • Capacitation Induces Cyclic Adenosine 3′,5′-Monophosphate-Dependent, but Apoptosis-Unrelated, Exposure of Aminophospholipids at the Apical Head Plasma Membrane of Boar Sperm Cells

    B.M. Gadella;R.A.P. Harrison

  • DNA damage in bovine sperm does not block fertilization and early embryonic development but induces apoptosis after the first cleavages.

    A N Fatehi;M M Bevers;E Schoevers;B A J Roelen

  • Oleic Acid Prevents Detrimental Effects of Saturated Fatty Acids on Bovine Oocyte Developmental Competence

    Hilde Aardema;Peter L.A.M. Vos;Francesca Lolicato;Bernard A.J. Roelen

  • The predictive value of semen analysis in the evaluation of stallion fertility.

    B Colenbrander;B M Gadella;T A E Stout

  • Sperm head membrane reorganisation during capacitation.

    Bart M Gadella;Pei-Shiue Tsai;Arjen Boerke;Ian A Brewis

  • Sperm surface changes and physiological consequences induced by sperm handling and storage

    Tamara Leahy;Bart M Gadella

  • Application of computer-assisted semen analysis to explain variations in pig fertility.

    M. L. W. J. Broekhuijse;E. Šoštarić;H. Feitsma;B. M. Gadella

  • Membrane changes during different stages of a freeze-thaw protocol for equine semen cryopreservation

    Deborah M Neild;Bart M Gadella;Marı́a Graciela Chaves;Marcelo H Miragaya

  • Capacitation-dependent concentration of lipid rafts in the apical ridge head area of porcine sperm cells.

    R.A. van Gestel;I.A. Brewis;P.R. Ashton;J.B. Helms

  • Capacitation induces tyrosine phosphorylation of proteins in the boar sperm plasma membrane

    F. M. Flesch;B. Colenbrander;L. M. G. Van Golde;B. M. Gadella

  • Caspase-Independent Exposure of Aminophospholipids and Tyrosine Phosphorylation in Bicarbonate Responsive Human Sperm Cells

    K.J. de Vries;T. Wiedmer;P.J. Sims;B.M. Gadella

  • Glycolipid migration from the apical to the equatorial subdomains of the sperm head plasma membrane precedes the acrosome reaction. Evidence for a primary capacitation event in boar spermatozoa

    B. M. Gadella;M. Lopes-Cardozo;L. M. G. Van Golde;B. Colenbrander

  • Capacitation and the acrosome reaction in equine sperm.

    B.M. Gadella;R. Rathi;J.F.H.M. Brouwers;T.A.E. Stout

  • Phosphatidylinositol 4-Kinaseβ Is Critical for Functional Association of rab11 with the Golgi Complex

    Petra de Graaf;Wilbert T. Zwart;Remco A.J. van Dijken;Magdalena Deneka

  • Lipid peroxide formation in relation to membrane stability of fresh and frozen thawed stallion spermatozoa.

    D.M. Neild;J.F.H.M. Brouwers;B. Colenbrander;A. Agüero

  • Capacitation-dependent reorganization of microdomains in the apical sperm head plasma membrane: Functional relationship with zona binding and the zona-induced acrosome reaction

    A. Boerke;P.S. Tsai;N. Garcia-Gil;I.A. Brewis

  • Bovine Cumulus Cells Protect Maturing Oocytes from Increased Fatty Acid Levels by Massive Intracellular Lipid Storage

    Hilde Aardema;Francesca Lolicato;Chris H.A. van de Lest;Jos F. Brouwers

  • Use of lectins to characterize plasma membrane preparations from boar spermatozoa: a novel technique for monitoring membrane purity and quantity.

    F. M. Flesch;W. F. Voorhout;B. Colenbrander;L. M. G. Van Golde

  • Bicarbonate and its role in mammalian sperm function

    B.M Gadella;R.A van Gestel

Frequent Co-Authors

Ben Colenbrander
Ben Colenbrander Utrecht University
Ann Van Soom
Ann Van Soom Ghent University
Bernard A.J. Roelen
Bernard A.J. Roelen Utrecht University
L.M.G. Van Golde
L.M.G. Van Golde Utrecht University
Marca H. M. Wauben
Marca H. M. Wauben Utrecht University
Paul J. Coffer
Paul J. Coffer Utrecht University
Arie J. Verkleij
Arie J. Verkleij Utrecht University
Dirk G. de Rooij
Dirk G. de Rooij Utrecht University
Jos Malda
Jos Malda Utrecht University
Peter J. Sims
Peter J. Sims University of Rochester

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