World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
12348
World Ranking
10911
National Ranking
294

Overview

Brett Nixon is affiliated with the University of Newcastle Australia. Their research spans multiple fields including Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on Reproductive Medicine and Molecular Biology within these broader disciplines.

The scientist's work is strongly represented in topics related to reproductive biology, with main areas of study including:

  • Sperm and Testicular Function
  • Reproductive Biology and Fertility
  • Glioma Diagnosis and Treatment
  • Reproductive System and Pregnancy
  • Cancer, Hypoxia, and Metabolism
  • Renal and related cancers
  • Advanced Proteomics Techniques and Applications

Recent publications reflect a diverse scope of inquiry, detailing investigations into molecular changes, metabolic differentiation, and cancer treatments. Notable papers include:

  • "Molecular Changes Induced by Oxidative Stress that Impair Human Sperm Motility" (2020) published in Antioxidants
  • "Roles of male reproductive tract extracellular vesicles in reproduction" (2020) in American Journal of Reproductive Immunology
  • "Metabolic Changes Accompanying Spermatogonial Stem Cell Differentiation" (2020) in Developmental Cell
  • "ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma" (2023) in Cancer Research
  • "The Sins of Our Forefathers: Paternal Impacts on De Novo Mutation Rate and Development" (2020) in Annual Review of Genetics

Brett Nixon frequently collaborates with a group of coauthors, evidencing ongoing partnerships reflected in publication records. Frequent collaborators include:

  • David A. Skerrett-Byrne
  • Matthew D. Dun
  • Elizabeth G. Bromfield
  • Amanda L. Anderson
  • Geoffry N. De Iuliis

The scientist publishes regularly in a range of venues, with multiple publications appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuro-Oncology
  • Reproduction Fertility and Development
  • PROTEOMICS
  • Frontiers in Cell and Developmental Biology

Brett Nixon has contributed to academic literature through book publications, including the book titled "Manual of Sperm Function Testing in Human Assisted Reproduction" published by Cambridge University Press in 2021.

Best Publications

  • Genome analysis of the platypus reveals unique signatures of evolution

    Wesley C. Warren;La Deana W. Hillier;Jennifer A. Marshall Graves;Ewan Birney

  • DNA Damage in Human Spermatozoa Is Highly Correlated with the Efficiency of Chromatin Remodeling and the Formation of 8-Hydroxy-2′-Deoxyguanosine, a Marker of Oxidative Stress

    Geoffry N. De Iuliis;Laura K. Thomson;Lisa A. Mitchell;Jane M. Finnie

  • Development of a Novel Electrophoretic System for the Isolation of Human Spermatozoa

    C. Ainsworth;B. Nixon;R.J. Aitken

  • Proteomic changes in mammalian spermatozoa during epididymal maturation.

    R. John Aitken;Brett Nixon;Minjie Lin;Adam J. Koppers

  • Tyrosine phosphorylation activates surface chaperones facilitating sperm-zona recognition.

    Kelly L. Asquith;Rosa M. Baleato;Eileen A. McLaughlin;Brett Nixon

  • Sperm capacitation: a distant landscape glimpsed but unexplored.

    R. John Aitken;Brett Nixon

  • Characterisation of mouse epididymosomes reveals a complex profile of microRNAs and a potential mechanism for modification of the sperm epigenome.

    Jackson N. Reilly;Eileen A. McLaughlin;Eileen A. McLaughlin;Simone J. Stanger;Amanda L. Anderson

  • Are sperm capacitation and apoptosis the opposite ends of a continuum driven by oxidative stress

    Robert J Aitken;Mark A Baker;Brett Nixon

  • The MicroRNA Signature of Mouse Spermatozoa Is Substantially Modified During Epididymal Maturation

    Brett Nixon;Simone J. Stanger;Bettina P. Mihalas;Jackson N. Reilly

  • Melatonin Prevents Postovulatory Oocyte Aging in the Mouse and Extends the Window for Optimal Fertilization In Vitro

    Tessa Lord;Brett Nixon;Keith T. Jones;R. John Aitken

  • Molecular Changes Induced by Oxidative Stress that Impair Human Sperm Motility.

    Karolina Nowicka-Bauer;Brett Nixon

  • Characteristics of the Epididymal Luminal Environment Responsible for Sperm Maturation and Storage.

    Wei Zhou;Geoffry N De Iuliis;Matthew D Dun;Brett Nixon

  • Transgenerational inheritance: how impacts to the epigenetic and genetic information of parents affect offspring health.

    Miguel João Xavier;Shaun D Roman;R John Aitken;Brett Nixon

  • The Identification of Mouse Sperm-Surface-Associated Proteins and Characterization of Their Ability to Act as Decapacitation Factors

    Brett Nixon;David A. MacIntyre;David A. MacIntyre;Lisa A. Mitchell;Gerard M. Gibbs

  • miRNA and mammalian male germ cells

    S.C. McIver;S.D. Roman;B. Nixon;E.A. McLaughlin

  • The molecular chaperone HSPA2 plays a key role in regulating the expression of sperm surface receptors that mediate sperm-egg recognition.

    Kate A. Redgrove;Brett Nixon;Mark A. Baker;Louise Hetherington

  • The role of molecular chaperones in spermatogenesis and the post-testicular maturation of mammalian spermatozoa

    Matthew D. Dun;R. John Aitken;R. John Aitken;Brett Nixon

  • Localization and Significance of Molecular Chaperones, Heat Shock Protein 1, and Tumor Rejection Antigen gp96 in the Male Reproductive Tract and During Capacitation and Acrosome Reaction

    Kelly L. Asquith;Amanda J. Harman;Eileen A. McLaughlin;Brett Nixon

  • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer (Nature (2007) 449, (682-688))

    Li Ma;Julie Teruya-Feldstein;Robert A. Weinberg

  • The molecular chaperone HSPA2 plays a key role in regulating the expression of sperm surface receptors that mediate sperm-egg recognition | NOVA. The University of Newcastle's Digital Repository

    Kate A. Redgrove;Brett Nixon;Mark A. Baker;Louise Hetherington

Frequent Co-Authors

R. John Aitken
R. John Aitken University of Newcastle Australia
Eileen A. McLaughlin
Eileen A. McLaughlin University of Wollongong
Moira K O'Bryan
Moira K O'Bryan University of Melbourne
Mark A. Baker
Mark A. Baker University of Newcastle Australia
Heath Ecroyd
Heath Ecroyd University of Wollongong
Adam McCluskey
Adam McCluskey University of Newcastle Australia
Frank Grützner
Frank Grützner University of Adelaide
Ewan Birney
Ewan Birney European Molecular Biology Laboratory
LaDeana W. Hillier
LaDeana W. Hillier University of Washington
Katherine Belov
Katherine Belov University of Sydney

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