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D-Index & Metrics

Biology and Biochemistry

D-Index
90
Citations
35262
World Ranking
2405
National Ranking
1276

Overview

Yuji Mishina is affiliated with the University of Michigan-Ann Arbor in the United States. Their research spans fields in Biochemistry, Genetics and Molecular Biology as well as Medicine, with a particular focus on Molecular Biology, Genetics, Oncology, Rheumatology, and Surgery.

The main research topics explored include:

  • TGF-β signaling in diseases
  • Heterotopic Ossification and Related Conditions
  • Bone health and treatments
  • Bone Metabolism and Diseases
  • Hedgehog Signaling Pathway Studies
  • Cleft Lip and Palate Research
  • Dental development and anomalies

Mishina has published numerous scientific papers, with a selection of recent publications covering various aspects of molecular and developmental biology, bone remodeling, and cancer treatment:

  • Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing, 2020, Nature Communications
  • Macropore design of tissue engineering scaffolds regulates mesenchymal stem cell differentiation fate, 2021, Biomaterials
  • Roles of osteoclasts in alveolar bone remodeling, 2022, genesis
  • Human-chimpanzee fused cells reveal cis-regulatory divergence underlying skeletal evolution, 2021, Nature Genetics
  • LXH254, a Potent and Selective ARAF-Sparing Inhibitor of BRAF and CRAF for the Treatment of MAPK-Driven Tumors, 2020, Clinical Cancer Research

Frequent co-authors collaborating with Yuji Mishina include:

  • Honghao Zhang
  • Hiroki Ueharu
  • Haichun Pan
  • W. Benton Swanson
  • Jingwen Yang

Publication venues where Mishina's work is often featured are:

  • Bone
  • genesis
  • UNC Libraries
  • Biochemical and Biophysical Research Communications
  • bioRxiv (Cold Spring Harbor Laboratory)

The scope of Mishina's contributions broadly covers mechanistic studies related to bone metabolism and genetic regulation, examining cellular processes such as osteoclast function and mesenchymal stem cell differentiation. Their work includes investigation of signaling pathways and developmental genetics applied to pathological conditions affecting skeletal and craniofacial features.

Best Publications

  • Identification of the haematopoietic stem cell niche and control of the niche size

    Jiwang Zhang;Chao Niu;Ling Ye;Haiyang Huang

  • Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction

    Hidemasa Oh;Steven B. Bradfute;Teresa D. Gallardo;Teruya Nakamura

  • Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

    Shih Min A Huang;Yuji M. Mishina;Shanming Liu;Atwood Cheung

  • BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt–β-catenin signaling

    Xi C. He;Jiwang Zhang;Wei Gang Tong;Ossama Tawfik

  • Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis.

    Yuji Mishina;Atsushi Suzuki;Naoto Ueno;Richard R. Behringer

  • BMP type I receptor inhibition reduces heterotopic ossification

    Paul B Yu;Donna Y Deng;Carol S Lai;Charles C Hong

  • BMP4 supports self-renewal of embryonic stem cells by inhibiting mitogen-activated protein kinase pathways

    Xiaoxia Qi;Teng-Guo Li;Jing Hao;Jie Hu

  • Oct4/Sox2-Regulated miR-302 Targets Cyclin D1 in Human Embryonic Stem Cells

    Deborah A. Greer Card;Pratibha B. Hebbar;Leping Li;Kevin W. Trotter

  • Requirement of Bmpr1a for Müllerian duct regression during male sexual development.

    Soazik P. Jamin;Nelson A. Arango;Yuji Mishina;Mark C. Hanks

  • Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo.

    Byeong S. Yoon;Dmitry A. Ovchinnikov;Isaac Yoshii;Yuji Mishina

  • Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development.

    Thomas Andl;Kyung Ahn;Alladin Kairo;Emily Y. Chu

  • Histone demethylase JHDM2A is critical for Tnp1 and Prm1 transcription and spermatogenesis.

    Yuki Okada;Yuki Okada;Greg Scott;Manas K. Ray;Yuji Mishina

  • Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat

    Tim J. Schulz;Ping Huang;Tian Lian Huang;Ruidan Xue;Ruidan Xue

  • Genetic analysis of the Müllerian-inhibiting substance signal transduction pathway in mammalian sexual differentiation.

    Yuji Mishina;Rodolfo Rey;Milton J. Finegold;Martin M. Matzuk

  • Deletion of dentin matrix protein-1 leads to a partial failure of maturation of predentin into dentin, hypomineralization, and expanded cavities of pulp and root canal during postnatal tooth development.

    Ling Ye;Mary MacDougall;Shubin Zhang;Yixia Xie

  • Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A - TCF7L2 fusion

    Adam J. Bass;Adam J. Bass;Michael S. Lawrence;Lear E. Brace;Alex H. Ramos;Alex H. Ramos

  • Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-γ agonists

    Kengo Shimono;Wei En Tung;Wei En Tung;Christine MacOlino;Amber Hsu Tsai Chi

  • BMP signaling and early embryonic patterning

    Satoshi Kishigami;Yuji Mishina

  • Generation of Bmpr/Alk3 conditional knockout mice.

    Yuji Mishina;Yuji Mishina;Mark C. Hanks;Shigeto Miura;Michelle D. Tallquist

  • Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3

    Vinciane Gaussin;Tom Van de Putte;Yuji Mishina;Mark C. Hanks

Frequent Co-Authors

Vesa Kaartinen
Vesa Kaartinen University of Michigan–Ann Arbor
Richard R. Behringer
Richard R. Behringer The University of Texas MD Anderson Cancer Center
Jian Q. Feng
Jian Q. Feng Texas A&M University
Jun Ninomiya-Tsuji
Jun Ninomiya-Tsuji North Carolina State University
Chu-Xia Deng
Chu-Xia Deng University of Macau
Michael D. Schneider
Michael D. Schneider Imperial College London
Mitsuo Yamauchi
Mitsuo Yamauchi University of North Carolina at Chapel Hill
Karen M. Lyons
Karen M. Lyons University of California, Los Angeles
Linheng Li
Linheng Li Stowers Institute for Medical Research
James F. Martin
James F. Martin Baylor College of Medicine

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