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D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
19316
World Ranking
11147
National Ranking
288

Overview

Susana Lopes is affiliated with Leiden University Medical Center in the Netherlands and has an extensive body of research primarily in the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work spans multiple subfields including Molecular Biology, Public Health, Environmental and Occupational Health, Reproductive Medicine, Immunology, and Pediatrics, Perinatology, and Child Health.

The research topics covered by Lopes include Pluripotent Stem Cells Research, Renal and related cancers, Reproductive Biology and Fertility, CRISPR and Genetic Engineering, Reproductive System and Pregnancy, Prenatal Screening and Diagnostics, and Single-cell and spatial transcriptomics.

Frequent publication venues for Lopes include Human Reproduction, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, iScience, and Stem Cell Reports. These venues reflect the multidisciplinary nature of their research outputs, with a focus on reproductive biology and molecular techniques.

Among their recent papers are:

  • "ESHRE guideline: female fertility preservation†", 2020, Human Reproduction Open
  • "Rethinking organoid technology through bioengineering", 2020, Nature Materials
  • "Fast and efficient generation of knock-in human organoids using homology-independent CRISPR-Cas9 precision genome editing", 2020, Nature Cell Biology
  • "Human fetal microglia acquire homeostatic immune-sensing properties early in development", 2020, Science
  • "Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis", 2023, Nature Biotechnology

Lopes has collaborated frequently with several co-authors, including Björn Menten, Björn Heindryckx, Hans Clevers, Annekatrien Boel, and Dominic Stoop. The recurring nature of these collaborations indicates ongoing research partnerships in overlapping areas of study.

Best Publications

  • Derivation of pluripotent epiblast stem cells from mammalian embryos

    I. Gabrielle M. Brons;Lucy E. Smithers;Matthew W. B. Trotter;Peter Rugg-Gunn

  • Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

    Minoru Takasato;Minoru Takasato;Pei X. Er;Han Sheng Chiu;Barbara Maier

  • Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states.

    Katsuhiko Hayashi;Susana M. Chuva de Sousa Lopes;Fuchou Tang;M. Azim Surani

  • Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids

    Huili Hu;Huili Hu;Helmuth Gehart;Benedetta Artegiani;Carmen LÖpez-Iglesias

  • A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes

    Lynsey M. Cree;David C. Samuels;Susana Chuva De Sousa Lopes;Harsha Karur Rajasimha

  • MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis.

    Katsuhiko Hayashi;Susana M. Chuva de Sousa Lopes;Masahiro Kaneda;Fuchou Tang

  • Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology

    Harsha D Devalla;Verena Schwach;John W Ford;James T Milnes

  • Germ cell specification in mice.

    Katsuhiko Hayashi;Susana M. Chuva de Sousa Lopes;M. Azim Surani

  • Transcriptional autoregulation of the bone related CBFA1/RUNX2 gene.

    Hicham Drissi;Quyen Luc;A. Rauf Shakoori;Susana Chuva De Sousa Lopes

  • BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo

    Susana M. Chuva de Sousa Lopes;Bernard A.J. Roelen;Rui M. Monteiro;Roul Emmens

  • Rethinking organoid technology through bioengineering

    Elena Garreta;Roger D. Kamm;Susana M. Chuva de Sousa Lopes;Madeline A. Lancaster

  • Fast and efficient generation of knock-in human organoids using homology-independent CRISPR–Cas9 precision genome editing

    Benedetta Artegiani;Delilah Hendriks;Joep Beumer;Rutger Kok

  • Piwi Proteins and piRNAs in Mammalian Oocytes and Early Embryos

    Elke F. Roovers;David Rosenkranz;Mahdi Mahdipour;Chung-Ting Han

  • Memory CD4(+) T cells are generated in the human fetal intestine

    Na Li;Vincent van Unen;Tamim Abdelaal;Tamim Abdelaal;Nannan Guo

  • Generation of stella-GFP transgenic mice: a novel tool to study germ cell development.

    Bernhard Payer;Susana M. Chuva de Sousa Lopes;Sheila C. Barton;Caroline Lee

  • X chromosome activity in mouse XX primordial germ cells

    Susana M Chuva de Sousa Lopes;Katsuhiko Hayashi;Tanya C Shovlin;Will Mifsud

  • Human trophoblast invasion: new and unexpected routes and functions

    Gerit Moser;Karin Windsperger;Jürgen Pollheimer;Susana Chuva de Sousa Lopes;Susana Chuva de Sousa Lopes

  • Review of the disease course among adult ulcerative colitis population-based longitudinal cohorts

    Fernando Magro;Andreia Rodrigues;Ana Isabel Vieira;Francisco Portela

  • Transcriptome of human foetal heart compared with cardiomyocytes from pluripotent stem cells.

    Cathelijne W. van den Berg;Satoshi Okawa;Susana M. Chuva de Sousa Lopes;Liesbeth van Iperen

  • Tracking the progression of the human inner cell mass during embryonic stem cell derivation

    Thomas O'Leary;Björn Heindryckx;Sylvie Lierman;David van Bruggen

Frequent Co-Authors

Christine L. Mummery
Christine L. Mummery Leiden University Medical Center
Bernard A.J. Roelen
Bernard A.J. Roelen Utrecht University
An Zwijsen
An Zwijsen KU Leuven
Dieter Deforce
Dieter Deforce Ghent University
Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
M. Azim Surani
M. Azim Surani University of Cambridge
Björn Menten
Björn Menten Ghent University Hospital
Katsuhiko Hayashi
Katsuhiko Hayashi Osaka University
Frits Koning
Frits Koning Leiden University Medical Center
Boudewijn P. F. Lelieveldt
Boudewijn P. F. Lelieveldt Leiden University Medical Center

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