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Neuroscience

D-Index
67
Citations
12742
World Ranking
2935
National Ranking
120

Overview

Caterina Bendotti is affiliated with the Mario Negri Institute for Pharmacological Research in Italy. Their research primarily focuses on amyotrophic lateral sclerosis (ALS) and related neurodegenerative disorders. The scientist has contributed extensively to studies in medicine, particularly in neurology, molecular biology, and genetics, with significant attention to the cellular and molecular neuroscience of neurodegenerative diseases.

The main research topics in Bendotti's work include:

  • Amyotrophic Lateral Sclerosis Research
  • Neurogenetic and Muscular Disorders Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Muscle Physiology and Disorders
  • Parkinson's Disease Mechanisms and Treatments
  • Genetic Neurodegenerative Diseases
  • RNA Research and Splicing

The scientist has an extensive list of publications in prominent venues. Frequent publication platforms include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cells
  • International Journal of Molecular Sciences
  • Inflammation and Regeneration
  • Acta Neuropathologica Communications

Some of Bendotti's recent papers are:

  • "Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases," 2023, Nature Communications
  • "miR-129-5p: A key factor and therapeutic target in amyotrophic lateral sclerosis," 2020, Progress in Neurobiology
  • "Focus on the heterogeneity of amyotrophic lateral sclerosis," 2020, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
  • "Interplay between immunity and amyotrophic lateral sclerosis: Clinical impact," 2021, Neuroscience & Biobehavioral Reviews
  • "CXCL13/CXCR5 signalling is pivotal to preserve motor neurons in amyotrophic lateral sclerosis," 2020, EBioMedicine

Bendotti frequently collaborates with other researchers in the field. Notable coauthors include:

  • Giovanni Nardo
  • Paola Fabbrizio
  • Maria Chiara Trolese
  • Laura Pasetto
  • Valentina Bonetto

Their scientific contributions emphasize the relationship between molecular and cellular mechanisms and clinical manifestations in ALS and related neurodegenerative conditions. The integration of genetic, molecular, and physiological perspectives is a hallmark of their research output.

Best Publications

  • The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS)

    Valeria Crippa;Daniela Sau;Paola Rusmini;Alessandra Boncoraglio

  • Expression of amyloid precursor protein mRNAs in endothelial, neuronal and glial cells: modulation by interleukin-1.

    Gianluigi Forloni;Federica Demicheli;Sussana Giorgi;Caterina Bendotti

  • m-Chlorophenylpiperazine: A central serotonin agonist causing powerful anorexia in rats

    R. Samanin;T. Mennini;A. Ferraris;C. Bendotti

  • Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity

    Caterina Bendotti;Novella Calvaresi;Luca Chiveri;Alessandro Prelle

  • Mutation of SOD1 in ALS: a gain of a loss of function

    Daniela Sau;Silvia De Biasi;Laura Vitellaro-Zuccarello;Patrizia Riso

  • Mutant Copper-Zinc Superoxide Dismutase (SOD1) Induces Protein Secretion Pathway Alterations and Exosome Release in Astrocytes IMPLICATIONS FOR DISEASE SPREADING AND MOTOR NEURON PATHOLOGY IN AMYOTROPHIC LATERAL SCLEROSIS

    Manuela Basso;Silvia Pozzi;Massimo Tortarolo;Fabio Fiordaliso

  • Lessons from models of SOD1-linked familial ALS

    Caterina Bendotti;Maria Teresa Carrì

  • Neurochemical mechanism of action of drugs which modify feeding via the serotoninergic system

    S. Garattini;T. Mennini;C. Bendotti;R. Invernizzi

  • Transgenic SOD1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels.

    Caterina Bendotti;Massimo Tortarolo;Sachin K. Suchak;Novella Calvaresi

  • Protein nitration in a mouse model of familial amyotrophic lateral sclerosis: possible multifunctional role in the pathogenesis.

    Filippo Casoni;Manuela Basso;Tania Massignan;Elisabetta Gianazza

  • Persistent activation of p38 mitogen-activated protein kinase in a mouse model of familial amyotrophic lateral sclerosis correlates with disease progression

    M Tortarolo;P Veglianese;N Calvaresi;A Botturi

  • Immune system alterations in sporadic amyotrophic lateral sclerosis patients suggest an ongoing neuroinflammatory process

    Stefania Mantovani;Silvia Garbelli;Alessandra Pasini;Dario Alimonti

  • Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis†

    Cristina Cheroni;Marianna Marino;Massimo Tortarolo;Pietro Veglianese

  • Dysfunction of constitutive and inducible ubiquitin-proteasome system in amyotrophic lateral sclerosis: implication for protein aggregation and immune response.

    Caterina Bendotti;Marianna Marino;Cristina Cheroni;Elena Fontana

  • Distribution of GAP-43 mRNA in the adult rat brain

    Lawrence Kruger;Caterina Bendotti;Romano Rivolta;Rosario Samanin

  • 8-Hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) elicits eating in free-feeding rats by acting on central serotonin neurons.

    Unknown

  • Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases

    Unknown

  • Amyotrophic lateral sclerosis multiprotein biomarkers in peripheral blood mononuclear cells.

    Giovanni Nardo;Silvia Pozzi;Mauro Pignataro;Eliana Lauranzano

  • Treatment with lithium carbonate does not improve disease progression in two different strains of SOD1 mutant mice.

    Chiara Pizzasegola;Ilaria Caron;Cristina Daleno;Anna Ronchi

  • Glutamate AMPA receptors change in motor neurons of SOD1G93A transgenic mice and their inhibition by a noncompetitive antagonist ameliorates the progression of amytrophic lateral sclerosis-like disease

    Massimo Tortarolo;Giuliano Grignaschi;Novella Calvaresi;Eleonora Zennaro

  • Developmental and plasticity-related differential expression of two SNAP-25 isoforms in the rat brain.

    Ursula Boschert;Celestine O'Shaughnessy;Robin Dickinson;Michela Tessari

  • Activation of the p38MAPK cascade is associated with upregulation of TNF alpha receptors in the spinal motor neurons of mouse models of familial ALS.

    P. Veglianese;D. Lo Coco;D. Lo Coco;M. Bao Cutrona;R. Magnoni

  • The role of putative 5-HT1A and 5-HT1B receptors in the control of feeding in rats.

    Caterina Bendotti;Rosario Samanin

Frequent Co-Authors

Annamaria Vezzani
Annamaria Vezzani Mario Negri Institute for Pharmacological Research
Pamela J. Shaw
Pamela J. Shaw University of Sheffield
Eleonora Aronica
Eleonora Aronica University of Amsterdam
Michael P. Coleman
Michael P. Coleman University of Cambridge
Roberto W. Invernizzi
Roberto W. Invernizzi Mario Negri Institute for Pharmacological Research
Marina Bentivoglio
Marina Bentivoglio University of Verona

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