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Neuroscience

D-Index
96
Citations
34350
World Ranking
859
National Ranking
465

Overview

Lee J. Martin is affiliated with Johns Hopkins University School of Medicine in the United States. Their research primarily spans the field of medicine, with a focus on several subfields including pediatrics, perinatology and child health, neurology, molecular biology, radiology, nuclear medicine and imaging, and genetics.

The scientist's work concentrates on various topics, particularly:

  • Neonatal and fetal brain pathology
  • Amyotrophic Lateral Sclerosis (ALS) research
  • Neurogenetic and muscular disorders research
  • Advanced neuroimaging techniques and applications
  • Anesthesia and neurotoxicity research
  • Infectious encephalopathies and encephalitis
  • Neuroscience of respiration and sleep

Lee J. Martin has contributed extensively to scholarly literature, with recent notable papers including:

  • "DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations," 2020, Acta Neuropathologica Communications
  • "Human Motor Neurons With SOD1-G93A Mutation Generated From CRISPR/Cas9 Gene-Edited iPSCs Develop Pathological Features of Amyotrophic Lateral Sclerosis," 2020, Frontiers in Cellular Neuroscience
  • "Skeletal Muscle-Restricted Expression of Human SOD1 in Transgenic Mice Causes a Fatal ALS-Like Syndrome," 2020, Frontiers in Neurology
  • "Fractional anisotropy from diffusion tensor imaging correlates with acute astrocyte and myelin swelling in neonatal swine models of excitotoxic and hypoxic-ischemic brain injury," 2021, The Journal of Comparative Neurology
  • "Aberrant DNA and RNA Methylation Occur in Spinal Cord and Skeletal Muscle of Human SOD1 Mouse Models of ALS and in Human ALS: Targeting DNA Methylation Is Therapeutic," 2022, Cells

The frequent coauthors collaborating with Lee J. Martin include:

  • Jennifer K. Lee
  • Frances J. Northington
  • Ewa Kulikowicz
  • May Chen
  • Raymond C. Koehler

The scientist's research has been published repeatedly in several journals and venues, among which the most frequent are:

  • Cells
  • The Journal of Comparative Neurology
  • Endocrine Abstracts
  • Frontiers in Cellular Neuroscience
  • Journal of Magnetic Resonance Imaging

Lee J. Martin has also contributed to book literature, with a publication titled Essen, Trinken und Demenz released by Hogrefe Verlag in 2021.

Best Publications

  • Localization of neuronal and glial glutamate transporters

    Jeffrey D. Rothstein;Lee Martin;Allan I. Levey;Margaret Dykes-Hoberg

  • Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis.

    Jeffrey D. Rothstein;Marleen Van Kammen;Allan I. Levey;Lee J. Martin

  • Decreased Glutamate Transport by the Brain and Spinal Cord in Amyotrophic Lateral Sclerosis

    Jeffrey D. Rothstein;Lee J. Martin;Ralph W. Kuncl

  • Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death.

    Toshio Ohshima;Jerrold M. Ward;Chang Goo Huh;Glenn Longenecker

  • Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.

    Edward H. Koo;Sangram S. Sisodia;David R. Archer;Lee J. Martin

  • Neurodegeneration in Excitotoxicity, Global Cerebral Ischemia, and Target Deprivation: A Perspective on the Contributions of Apoptosis and Necrosis

    Lee J. Martin;Nael A. Al-Abdulla;Ansgar M. Brambrink;Jeffrey R. Kirsch

  • Parkinson's Disease α-Synuclein Transgenic Mice Develop Neuronal Mitochondrial Degeneration and Cell Death

    Lee J. Martin;Yan Pan;Ann C. Price;Wanda Sterling

  • Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease

    Chun I. Sze;Juan C. Troncoso;Claudia Kawas;Peter Mouton

  • AMPA glutamate receptor subunits are differentially distributed in rat brain

    L.J. Martin;C.D. Blackstone;A.I. Levey;R.L. Huganir

  • Glutamate transporter protein subtypes are expressed differentially during rat CNS development.

    Akiko Furuta;Jeffrey D. Rothstein;Lee J. Martin

  • Cellular localization of a metabotropic glutamate receptor in rat brain

    Lee J. Martin;Craig D. Blackstone;Richard L. Huganir;Donald L. Price

  • Apoptosis Has a Prolonged Role in the Neurodegeneration after Hypoxic Ischemia in the Newborn Rat

    Wako Nakajima;Akira Ishida;Mary S. Lange;Kathleen L. Gabrielson

  • Excitotoxic neuronal death in the immature brain is an apoptosis‐necrosis morphological continuum

    Carlos Portera-Cailliau;Donald L. Price;Lee J. Martin

  • Epigenetic Regulation of Motor Neuron Cell Death Through DNA Methylation

    Barry A. Chestnut;Qing Chang;Ann Price;Catherine Lesuisse

  • Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism.

    Lee J. Martin

  • Neuronal cell death in neonatal hypoxia-ischemia

    Frances J. Northington;Raul Chavez-Valdez;Raul Chavez-Valdez;Lee J. Martin

  • Non‐NMDA and NMDA receptor‐mediated excitotoxic neuronal deaths in adult brain are morphologically distinct: Further evidence for an apoptosis‐necrosis continuum

    Carlos Portera-Cailliau;Donald L. Price;Lee J. Martin

  • Early Neurodegeneration after Hypoxia-Ischemia in Neonatal Rat Is Necrosis while Delayed Neuronal Death Is Apoptosis.

    Frances J. Northington;Donna M. Ferriero;Ernest M. Graham;Richard J. Traystman

  • Skeletal muscle-restricted expression of human SOD1 causes motor neuron degeneration in transgenic mice

    Margaret Wong;Lee J. Martin

  • Comparative evaluation of synaptophysin-based methods for quantification of synapses.

    Michael E. Calhoun;Mathias Jucker;Lee J. Martin;Gopal Thinakaran

Frequent Co-Authors

Sangram S. Sisodia
Sangram S. Sisodia University of Chicago
Vassilis E. Koliatsos
Vassilis E. Koliatsos Johns Hopkins University School of Medicine
Jeffrey D. Rothstein
Jeffrey D. Rothstein Johns Hopkins University
Richard L. Huganir
Richard L. Huganir Johns Hopkins University School of Medicine
Stephen D. Ginsberg
Stephen D. Ginsberg Nathan Kline Institute for Psychiatric Research
Carlos Portera-Cailliau
Carlos Portera-Cailliau University of California, Los Angeles
Linda C. Cork
Linda C. Cork Stanford University
Donna M. Ferriero
Donna M. Ferriero University of California, San Francisco
Allan I. Levey
Allan I. Levey Emory University
Mary E. Blue
Mary E. Blue Kennedy Krieger Institute

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