World's Best Scientists 2026 revealed!
Jean-Philippe Loeffler

Jean-Philippe Loeffler

D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
14970
World Ranking
7496
National Ranking
248

Jean-Philippe Loeffler publications per year

1984: 2 publications 1985: 1 publications 1986: 2 publications 1987: 2 publications 1988: 3 publications 1989: 3 publications 1990: 5 publications 1991: 3 publications 1992: 4 publications 1993: 3 publications 1994: 6 publications 1995: 4 publications 1996: 3 publications 1997: 6 publications 1998: 3 publications 1999: 8 publications 2000: 10 publications 2001: 5 publications 2002: 12 publications 2003: 8 publications 2004: 7 publications 2005: 8 publications 2006: 6 publications 2007: 11 publications 2008: 12 publications 2009: 7 publications 2010: 7 publications 2011: 4 publications 2012: 5 publications 2013: 7 publications 2014: 1 publications 2015: 5 publications 2016: 4 publications 2017: 4 publications 2018: 1 publications 2019: 2 publications 2020: 5 publications 2021: 4 publications 2022: 2 publications 2023: 12 publications 2024: 0 publications 2025: 1 publications
1984 2025

208 publications in total across all disciplines

Jean-Philippe Loeffler publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Jean-Philippe Loeffler sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 175 publications — 39th percentile

39% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Jean-Philippe Loeffler D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Jean-Philippe Loeffler sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 69 D-Index — 63rd percentile

63% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Jean-Philippe Loeffler is affiliated with the University of Strasbourg in France. Their research primarily focuses on medical sciences, with a specialization in neurology, genetics, physiology, molecular biology, and cellular and molecular neuroscience. Their work emphasizes amyotrophic lateral sclerosis (ALS) research, Parkinson's disease mechanisms and treatments, neurogenetic and muscular disorders, lysosomal storage disorders, muscle physiology and disorders, genetic neurodegenerative diseases, and mitochondrial function and pathology.

The most frequent publication venues for Loeffler include Brain Communications, bioRxiv (Cold Spring Harbor Laboratory), Seminars in Cell and Developmental Biology, British Journal of Pharmacology, and European Journal of Pharmacology.

Among their recent papers are:

  • "Altered skeletal muscle glucose-fatty acid flux in amyotrophic lateral sclerosis," 2020, Brain Communications
  • "Sphingolipids metabolism alteration in the central nervous system: Amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases," 2020, Seminars in Cell and Developmental Biology
  • "Repurposing of Trimetazidine for amyotrophic lateral sclerosis: A study in SOD1G93Amice," 2021, British Journal of Pharmacology
  • "Drug repositioning in neurodegeneration: An overview of the use of ambroxol in neurodegenerative diseases," 2020, European Journal of Pharmacology
  • "Alteration of the Neuromuscular Junction and Modifications of Muscle Metabolism in Response to Neuron-Restricted Expression of the CHMP2Bintron5 Mutant in a Mouse Model of ALS-FTD Syndrome," 2022, Biomolecules

Loeffler collaborates frequently with several coauthors, including Shyuan T. Ngo, Frédérique René, Frederik J. Steyn, Alberto Ferri, and Cristiana Valle.

Best Publications

  • Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA

    Jean-Paul Behr;Barbara Demeneix;Jean-Philippe Loeffler;Jose Perez-Mutul

  • Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: benefit of a high-energy diet in a transgenic mouse model.

    Luc Dupuis;Hugues Oudart;Frédérique René;Jose-Luis Gonzalez de Aguilar

  • Energy metabolism in amyotrophic lateral sclerosis.

    Luc Dupuis;Luc Dupuis;Pierre-François Pradat;Albert C Ludolph;Jean-Philippe Loeffler;Jean-Philippe Loeffler

  • Critical loss of CBP/p300 histone acetylase activity by caspase-6 during neurodegeneration.

    Caroline Rouaux;Natasa Jokic;Corinne Mbebi;Stephanie Boutillier

  • Lipopolyamines, their preparation and their use

    Jean-Paul Behr;Jean-Philippe Loeffler

  • Guidelines for preclinical animal research in ALS/MND: A consensus meeting.

    Albert C. Ludolph;Caterina Bendotti;Eran Blaugrund;Adriano Chio

  • Sodium Valproate Exerts Neuroprotective Effects In Vivo through CREB-Binding Protein-Dependent Mechanisms But Does Not Improve Survival in an Amyotrophic Lateral Sclerosis Mouse Model

    Caroline Rouaux;Irina Panteleeva;Frédérique René;Jose-Luis Gonzalez de Aguilar

  • Spatial Memory Consolidation is Associated with Induction of Several Lysine-Acetyltransferase (Histone Acetyltransferase) Expression Levels and H2B/H4 Acetylation-Dependent Transcriptional Events in the Rat Hippocampus

    Olivier Bousiges;Anne Pereira de Vasconcelos;Romain Neidl;Romain Neidl;Brigitte Cosquer

  • A Ruthenium-Containing Organometallic Compound Reduces Tumor Growth through Induction of the Endoplasmic Reticulum Stress Gene CHOP

    Xiangjun Meng;Mili L. Leyva;Marjorie Jenny;Isabelle Gross

  • Neuromuscular junction destruction during amyotrophic lateral sclerosis: insights from transgenic models

    Luc Dupuis;Jean-Philippe Loeffler;Jean-Philippe Loeffler

  • Muscle Mitochondrial Uncoupling Dismantles Neuromuscular Junction and Triggers Distal Degeneration of Motor Neurons

    Luc Dupuis;Luc Dupuis;Jose-Luis Gonzalez de Aguilar;Jose-Luis Gonzalez de Aguilar;Andoni Echaniz-Laguna;Andoni Echaniz-Laguna;Judith Eschbach;Judith Eschbach

  • A metabolic switch toward lipid use in glycolytic muscle is an early pathologic event in a mouse model of amyotrophic lateral sclerosis

    Lavinia Palamiuc;Lavinia Palamiuc;Anna Schlagowski;Shyuan T Ngo;Aurelia Vernay;Aurelia Vernay

  • Nogo-A, -B, and -C Are Found on the Cell Surface and Interact Together in Many Different Cell Types

    Dana A. Dodd;Barbara Niederoest;Stefan Bloechlinger;Luc Dupuis

  • The Role of Skeletal Muscle in Amyotrophic Lateral Sclerosis

    Jean-Philippe Loeffler;Jean-Philippe Loeffler;Gina Picchiarelli;Gina Picchiarelli;Luc Dupuis;Luc Dupuis;Jose-Luis Gonzalez De Aguilar;Jose-Luis Gonzalez De Aguilar

  • Nogo provides a molecular marker for diagnosis of amyotrophic lateral sclerosis.

    Luc Dupuis;Jose-Luis Gonzalez de Aguilar;Franck di Scala;Frédérique Rene

  • Impaired glucose tolerance in patients with amyotrophic lateral sclerosis.

    Pierre-Francois Pradat;Gaelle Bruneteau;Paul H Gordon;Luc Dupuis

  • Ruthenium (II)-Derived Organometallic Compounds Induce Cytostatic and Cytotoxic Effects on Mammalian Cancer Cell Lines through p53-Dependent and p53-Independent Mechanisms

    Christian Gaiddon;Pierre Jeannequin;Pierre Bischoff;Michel Pfeffer

  • The neurite outgrowth inhibitor Nogo-A promotes denervation in an amyotrophic lateral sclerosis model

    Natasa Jokic;Jose-Luis Gonzalez de Aguilar;Leda Dimou;Shuo Lin

  • Gene transfer into primary and established mammalian cell lines with lipopolyamine-coated DNA

    Jean-Philippe Loeffler;Jean-Paul Behr

  • Targeting CREB-binding protein (CBP) loss of function as a therapeutic strategy in neurological disorders

    Caroline Rouaux;Jean-Philippe Loeffler;Anne-Laurence Boutillier

Frequent Co-Authors

Jean-Paul Behr
Jean-Paul Behr Centre national de la recherche scientifique, CNRS
Albert C. Ludolph
Albert C. Ludolph University of Ulm
Claude B. Sirlin
Claude B. Sirlin University of California, San Diego
Barbara A. Demeneix
Barbara A. Demeneix Centre national de la recherche scientifique, CNRS
Michael Spedding
Michael Spedding DuPont (United States)
André Delacourte
André Delacourte University of Lille
Luc Buée
Luc Buée University of Lille
Bradley T. Hyman
Bradley T. Hyman Harvard University
Rita Guerreiro
Rita Guerreiro Van Andel Institute
Jose Bras
Jose Bras Van Andel Institute

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