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D-Index & Metrics

Molecular Biology

D-Index
79
Citations
46732
World Ranking
1022
National Ranking
80

Overview

Jennifer Nichols is affiliated with the University of Cambridge in the United Kingdom and focuses primarily on Biochemistry, Genetics, and Molecular Biology. Their research portfolio includes 157 publications within this broad field, with a significant emphasis on Molecular Biology, comprising 140 of these works.

The scientist's contributions span several specialized subfields, including Public Health, Environmental and Occupational Health, Surgery, Genetics, and Biomedical Engineering. Their research topics are clearly delineated and demonstrate a strong focus on Pluripotent Stem Cells Research, featuring in 94 publications. Other key topics include Single-cell and Spatial Transcriptomics, CRISPR and Genetic Engineering, Reproductive Biology and Fertility, Renal and related cancers, Congenital heart defects research, and Epigenetics and DNA Methylation.

Jennifer Nichols's publications frequently appear in several notable venues, with the highest number in bioRxiv (Cold Spring Harbor Laboratory) totaling 28 publications. Other frequent venues of publication include Cell stem cell with 7 papers, Development with 5, Genome biology and Nature Cell Biology each with 3 publications.

Their recent papers include:

  • Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids, 2020, Nature
  • Human naive epiblast cells possess unrestricted lineage potential, 2021, Cell stem cell
  • Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis, 2021, Nature Biotechnology
  • Naive stem cell blastocyst model captures human embryo lineage segregation, 2021, Cell stem cell
  • Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency, 2020, Cell stem cell

Throughout their career, Jennifer Nichols has collaborated with various researchers, with frequent co-authors including Berthold Göttgens (17 joint publications), John C. Marioni (14), Ayaka Yanagida (13), Takuya Azami (12), and Giuliano Giuseppe Stirparo (11). These collaborative relationships suggest interdisciplinary and multi-laboratory efforts in advancing molecular and cellular biology.

Best Publications

  • Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4

    Jennifer Nichols;Branko Zevnik;Konstantinos Anastassiadis;Hitoshi Niwa

  • FUNCTIONAL EXPRESSION CLONING OF NANOG, A PLURIPOTENCY SUSTAINING FACTOR IN EMBRYONIC STEM CELLS

    Ian Chambers;Douglas Colby;Morag Robertson;Jennifer Nichols

  • The ground state of embryonic stem cell self-renewal

    Qi-Long Ying;Jason Wray;Jennifer Nichols;Laura Batlle-Morera

  • BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3

    Qi Long Ying;Jennifer Nichols;Ian Chambers;Austin Smith

  • Changing potency by spontaneous fusion

    Qi-Long Ying;Jennifer Nichols;Edward P Evans;Austin G Smith

  • Naive and primed pluripotent states.

    Jennifer Nichols;Austin Smith;Austin Smith

  • Nanog safeguards pluripotency and mediates germline development.

    Ian Chambers;Jose Silva;Douglas Colby;Jennifer Nichols;Jennifer Nichols

  • Nanog is the gateway to the pluripotent ground state.

    Jose Silva;Jose Silva;Jennifer Nichols;Jennifer Nichols;Thorold W. Theunissen;Thorold W. Theunissen;Ge Guo;Ge Guo

  • Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition

    José Teodoro Silva;Ornella Barrandon;Ornella Barrandon;Jennifer Nichols;Jennifer Nichols;Jitsutaro Kawaguchi;Jitsutaro Kawaguchi

  • Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human

    Yasuhiro Takashima;Ge Guo;Remco Loos;Jennifer Nichols

  • The Transcriptional and Epigenomic Foundations of Ground State Pluripotency

    Hendrik Marks;Tüzer Kalkan;Roberta Menafra;Sergey Denissov

  • Klf4 reverts developmentally programmed restriction of ground state pluripotency.

    Ge Guo;Jian Yang;Jian Yang;Jennifer Nichols;Jennifer Nichols;John Simon Hall;John Simon Hall

  • A single-cell molecular map of mouse gastrulation and early organogenesis.

    Blanca Pijuan-Sala;Jonathan A. Griffiths;Carolina Guibentif;Tom W. Hiscock

  • Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells.

    Tom Burdon;Craig Stracey;Ian Chambers;Jennifer Nichols

  • Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo

    Jennifer Nichols;Jose Silva;Jose Silva;Mila Roode;Mila Roode;Austin Smith;Austin Smith

  • Regulated Fluctuations in Nanog Expression Mediate Cell Fate Decisions in Embryonic Stem Cells

    Tibor Kalmár;Chea Lu Lim;Penelope Hayward;Silvia Muñoz-Descalzo

  • The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification

    Thorsten Boroviak;Remco Loos;Paul Bertone;Austin Smith

  • Establishment of germ-line-competent embryonic stem (ES) cells using differentiation inhibiting activity

    J. Nichols;E.P. Evans;A.G. Smith

  • The NuRD component Mbd3 is required for pluripotency of embryonic stem cells.

    Keisuke Kaji;Isabel Martín Caballero;Ruth MacLeod;Jennifer Nichols

  • Lineage-Specific Profiling Delineates the Emergence and Progression of Naive Pluripotency in Mammalian Embryogenesis

    Thorsten Edwin Boroviak;Remco Loos;Patrick Lombard;Junko Okahara

Frequent Co-Authors

Austin Smith
Austin Smith University of Exeter
Wolf Reik
Wolf Reik Babraham Institute
John C. Marioni
John C. Marioni European Bioinformatics Institute
Paul Bertone
Paul Bertone University of Cambridge
Ian Chambers
Ian Chambers University of Edinburgh
Berthold Göttgens
Berthold Göttgens University of Cambridge
Benjamin D. Simons
Benjamin D. Simons University of Cambridge
M. Azim Surani
M. Azim Surani University of Cambridge
Anna-Katerina Hadjantonakis
Anna-Katerina Hadjantonakis Memorial Sloan Kettering Cancer Center
Alfonso Martinez Arias
Alfonso Martinez Arias University of Cambridge

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