D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 68 Citations 41,589 107 World Ranking 1676 National Ranking 192

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Cellular differentiation
  • DNA

Her scientific interests lie mostly in Embryonic stem cell, Cell biology, Cellular differentiation, Induced pluripotent stem cell and Stem cell. Her Embryonic stem cell research is multidisciplinary, relying on both Inner cell mass and Blastocyst. Her research integrates issues of Genetics and Rex1 in her study of Cell biology.

In her study, Transcriptome, Chromatin, Epigenomics and Promoter is strongly linked to Molecular biology, which falls under the umbrella field of Cellular differentiation. Her biological study spans a wide range of topics, including Cell culture, Leukemia inhibitory factor, STAT3, Induced stem cells and Embryo. Her studies in Homeobox protein NANOG integrate themes in fields like SOX2 and KLF4.

Her most cited work include:

  • Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4 (2907 citations)
  • FUNCTIONAL EXPRESSION CLONING OF NANOG, A PLURIPOTENCY SUSTAINING FACTOR IN EMBRYONIC STEM CELLS (2873 citations)
  • The ground state of embryonic stem cell self-renewal (2574 citations)

What are the main themes of her work throughout her whole career to date?

The scientist’s investigation covers issues in Cell biology, Embryonic stem cell, Epiblast, Stem cell and Cellular differentiation. The study incorporates disciplines such as Homeobox protein NANOG and Induced pluripotent stem cell in addition to Cell biology. Embryonic stem cell is the subject of her research, which falls under Genetics.

Her study in Epiblast is interdisciplinary in nature, drawing from both Transcriptome, Germ layer and Endoderm. Her Stem cell study incorporates themes from KOSR, Immunology, NODAL, Induced stem cells and Cell fate determination. Her work deals with themes such as Progenitor cell, Transcription factor, Chromatin, Molecular biology and Epigenome, which intersect with Cellular differentiation.

She most often published in these fields:

  • Cell biology (90.51%)
  • Embryonic stem cell (74.05%)
  • Epiblast (49.37%)

What were the highlights of her more recent work (between 2017-2021)?

  • Cell biology (90.51%)
  • Epiblast (49.37%)
  • Embryonic stem cell (74.05%)

In recent papers she was focusing on the following fields of study:

Jennifer Nichols focuses on Cell biology, Epiblast, Embryonic stem cell, Stem cell and Embryo. Her Cell biology study combines topics from a wide range of disciplines, such as Cellular differentiation, Transcription factor and Homeobox protein NANOG, Induced pluripotent stem cell. Her Epiblast research incorporates themes from Reprogramming, Cell culture, Germ layer and Inner cell mass.

The Embryonic stem cell study combines topics in areas such as Cell, Transcriptome, Haematopoiesis and Blastocyst. She focuses mostly in the field of Stem cell, narrowing it down to matters related to Cell fate determination and, in some cases, CpG site, DNA hypomethylation, Somatic cell and Epigenetics. Her Embryo research includes elements of Phenotype and Brachyury.

Between 2017 and 2021, her most popular works were:

  • A single-cell molecular map of mouse gastrulation and early organogenesis. (238 citations)
  • Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human pre-implantation epiblast (91 citations)
  • Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning (90 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Cellular differentiation
  • DNA

Jennifer Nichols mainly investigates Cell biology, Induced pluripotent stem cell, Epiblast, Embryonic stem cell and Germ layer. Her studies deal with areas such as Cell culture and Mesoderm as well as Cell biology. Her Induced pluripotent stem cell research includes themes of Cellular differentiation and Cell fate determination.

Jennifer Nichols has researched Cellular differentiation in several fields, including Enhancer, TCF3, Transcription factor, RBPJ and Nanog Homeobox Protein. Her Embryonic stem cell research integrates issues from Transcriptome, Live cell imaging and Single-cell analysis. Her Homeobox protein NANOG research is multidisciplinary, relying on both Chromatin, XIST, X-inactivation, X chromosome and Gene silencing.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

FUNCTIONAL EXPRESSION CLONING OF NANOG, A PLURIPOTENCY SUSTAINING FACTOR IN EMBRYONIC STEM CELLS

Ian Chambers;Douglas Colby;Morag Robertson;Jennifer Nichols.
Cell (2003)

3975 Citations

Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4

Jennifer Nichols;Branko Zevnik;Konstantinos Anastassiadis;Hitoshi Niwa.
Cell (1998)

3933 Citations

The ground state of embryonic stem cell self-renewal

Qi-Long Ying;Jason Wray;Jennifer Nichols;Laura Batlle-Morera.
Nature (2008)

3027 Citations

BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3

Qi Long Ying;Jennifer Nichols;Ian Chambers;Austin Smith.
Cell (2003)

2519 Citations

Changing potency by spontaneous fusion

Qi-Long Ying;Jennifer Nichols;Edward P Evans;Austin G Smith.
Nature (2002)

2021 Citations

Naive and primed pluripotent states.

Jennifer Nichols;Jennifer Nichols;Austin Smith;Austin Smith.
Cell Stem Cell (2009)

1615 Citations

Nanog safeguards pluripotency and mediates germline development.

Ian Chambers;Jose Silva;Douglas Colby;Jennifer Nichols;Jennifer Nichols.
Nature (2007)

1609 Citations

Nanog is the gateway to the pluripotent ground state.

Jose Silva;Jose Silva;Jennifer Nichols;Jennifer Nichols;Thorold W. Theunissen;Thorold W. Theunissen;Ge Guo;Ge Guo.
Cell (2009)

1091 Citations

Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition

José Teodoro Silva;Ornella Barrandon;Ornella Barrandon;Jennifer Nichols;Jennifer Nichols;Jitsutaro Kawaguchi;Jitsutaro Kawaguchi.
PLOS Biology (2008)

920 Citations

The Transcriptional and Epigenomic Foundations of Ground State Pluripotency

Hendrik Marks;Tüzer Kalkan;Roberta Menafra;Sergey Denissov.
Cell (2012)

787 Citations

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