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Hitoshi Niwa

Hitoshi Niwa

D-Index & Metrics

Molecular Biology

D-Index
75
Citations
45412
World Ranking
1167
National Ranking
96

Overview

Hitoshi Niwa is affiliated with Kumamoto University in Japan. Their research spans multiple fields, predominantly in Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. The scientist has contributed extensively to the subfields of Molecular Biology, Cellular and Molecular Neuroscience, Physiology, Neurology, and Anesthesiology and Pain Medicine.

Their work covers various main topics including Pluripotent Stem Cells Research, Pain Mechanisms and Treatments, Airway Management and Intubation Techniques, Genomics and Chromatin Dynamics, Neuroscience and Neuropharmacology Research, Neuropeptides and Animal Physiology, and Anesthesia and Sedative Agents.

Selected recent papers authored or co-authored by Niwa include:

  • MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells, 2020, Developmental Cell
  • Meiosis-specific ZFP541 repressor complex promotes developmental progression of meiotic prophase towards completion during mouse spermatogenesis, 2021, Nature Communications
  • Establishment of bone marrow-derived M-CSF receptor-dependent self-renewing macrophages, 2020, Cell Death Discovery
  • Molecular detection of maturation stages in the developing kidney, 2020, Developmental Biology
  • Mesenchymal-epithelial transition regulates initiation of pluripotency exit before gastrulation, 2020, Development

Niwa frequently collaborates with several researchers, including Hiroharu Maegawa, Nayuka Usami, Chiho Kudo, Mariko Yamane, and Hiroshi Hanamoto.

Their publications have appeared in various scientific venues. Frequent outlets include Anesthesia Progress, bioRxiv (Cold Spring Harbor Laboratory), Biochemical and Biophysical Research Communications, Nature Communications, and PLoS ONE.

Best Publications

  • Efficient selection for high-expression transfectants with a novel eukaryotic vector

    Hitoshi Niwa;Ken-ichi Yamamura;Jun-ichi Miyazaki

  • Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells.

    Hitoshi Niwa;Jun-ichi Miyazaki;Austin G. Smith

  • Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4

    Jennifer Nichols;Branko Zevnik;Konstantinos Anastassiadis;Hitoshi Niwa

  • Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

    Hitoshi Niwa;Tom Burdon;Ian Chambers;Austin G Smith

  • Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells

    Shinji Masui;Yuhki Nakatake;Yayoi Toyooka;Daisuke Shimosato

  • Interaction between Oct3/4 and Cdx2 Determines Trophectoderm Differentiation

    Hitoshi Niwa;Yayoi Toyooka;Daisuke Shimosato;Dan Strumpf

  • How is pluripotency determined and maintained

    Hitoshi Niwa

  • The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass.

    Noriyuki Nishioka;Ken ichi Inoue;Kenjiro Adachi;Hiroshi Kiyonari

  • A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells

    Hitoshi Niwa;Kazuya Ogawa;Daisuke Shimosato;Kenjiro Adachi

  • Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2.

    Martha Hotz Vitaterna;Christopher P. Selby;Takeshi Todo;Hitoshi Niwa

  • Genome analysis of the platypus reveals unique signatures of evolution

    Wesley C. Warren;La Deana W. Hillier;Jennifer A. Marshall Graves;Ewan Birney

  • Retraction: Bidirectional developmental potential in reprogrammed cells with acquired pluripotency

    Haruko Obokata;Yoshiki Sasai;Hitoshi Niwa;Mitsutaka Kadota

  • Identification and characterization of subpopulations in undifferentiated ES cell culture

    Yayoi Toyooka;Daisuke Shimosato;Kazuhiro Murakami;Kadue Takahashi

  • Differentiation of embryonic stem cells is induced by GATA factors

    Junji Fujikura;Eiji Yamato;Shigenobu Yonemura;Kiminori Hosoda

  • Glucose Intolerance Caused by a Defect in the Entero-Insular Axis: A Study in Gastric Inhibitory Polypeptide Receptor Knockout Mice

    Kazumasa Miyawaki;Yuichiro Yamada;Hideki Yano;Hitoshi Niwa

  • Oct-3/4 and Sox2 Regulate Oct-3/4 Gene in Embryonic Stem Cells

    Sayaka Okumura-Nakanishi;Motoki Saito;Motoki Saito;Hitoshi Niwa;Fuyuki Ishikawa;Fuyuki Ishikawa

  • Molecular Pathway and Cell State Responsible for Dissociation-Induced Apoptosis in Human Pluripotent Stem Cells

    Masatoshi Ohgushi;Michiru Matsumura;Mototsugu Eiraku;Kazuhiro Murakami

  • MOLECULAR MECHANISM TO MAINTAIN STEM CELL RENEWAL OF ES CELLS

    Hitoshi Niwa

  • Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis

    Seiji Takashima;Masafumi Kitakaze;Masanori Asakura;Hiroshi Asanuma

  • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer (Nature (2007) 449, (682-688))

    Li Ma;Julie Teruya-Feldstein;Robert A. Weinberg

Frequent Co-Authors

Jun-ichi Miyazaki
Jun-ichi Miyazaki Osaka University
Minoru S.H. Ko
Minoru S.H. Ko Keio University
Austin Smith
Austin Smith University of Exeter
Kimi Araki
Kimi Araki Kumamoto University
Teruhiko Wakayama
Teruhiko Wakayama University of Yamanashi
Ken Ichi Yamamura
Ken Ichi Yamamura Kumamoto University
Yoshiki Sasai
Yoshiki Sasai Kyoto University
Takashi Yokota
Takashi Yokota Kanazawa University
Ian Chambers
Ian Chambers University of Edinburgh
Janet Rossant
Janet Rossant University of Toronto

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