D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 69 Citations 40,848 197 World Ranking 892 National Ranking 71

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Surgery

Embryonic stem cell, Cell biology, Molecular biology, Transcription factor and Cellular differentiation are his primary areas of study. Hitoshi Niwa interconnects Stem cell and Inner cell mass in the investigation of issues within Embryonic stem cell. His Cell biology research integrates issues from Inhibitory postsynaptic potential, Immunology, Germline and Leukemia inhibitory factor.

His research in Molecular biology intersects with topics in Cell culture, SOX2, Promoter, Reporter gene and Embryoid body. As part of his studies on Cellular differentiation, Hitoshi Niwa often connects relevant subjects like Oct-4. The various areas that Hitoshi Niwa examines in his Rex1 study include Cell potency, Nanog Homeobox Protein and Homeobox protein NANOG.

His most cited work include:

  • Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. (3148 citations)
  • Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4 (2907 citations)
  • Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3 (1341 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Cell biology, Embryonic stem cell, Molecular biology, Anesthesia and Cellular differentiation. His Cell biology research is multidisciplinary, relying on both Cell potency, Reprogramming, Immunology and Somatic cell. His Embryonic stem cell research is multidisciplinary, incorporating elements of Transcription factor and Stem cell.

His Molecular biology study incorporates themes from Cell culture, Inner cell mass, Gene, Transgene and Embryo. His Anesthesia study combines topics in areas such as Surgery and Blood pressure. His biological study spans a wide range of topics, including Nanog Homeobox Protein and Homeobox protein NANOG.

He most often published in these fields:

  • Cell biology (38.46%)
  • Embryonic stem cell (37.18%)
  • Molecular biology (20.51%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (38.46%)
  • Embryonic stem cell (37.18%)
  • Anesthesia (20.09%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cell biology, Embryonic stem cell, Anesthesia, Surgery and Cell. Hitoshi Niwa studies Stem cell, a branch of Cell biology. The Stem cell study combines topics in areas such as Germ layer and Endoderm.

The study incorporates disciplines such as Reprogramming, Epigenetics and Cellular differentiation in addition to Embryonic stem cell. His Cell research incorporates elements of Hippo signaling pathway, Cell culture, ASCL1 and Carcinogenesis. His work deals with themes such as Regulation of gene expression and Germ cell, which intersect with Transcription factor.

Between 2015 and 2021, his most popular works were:

  • The principles that govern transcription factor network functions in stem cells. (42 citations)
  • Zscan4 Is Activated after Telomere Shortening in Mouse Embryonic Stem Cells (28 citations)
  • MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells. (27 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Surgery

Hitoshi Niwa spends much of his time researching Cell biology, Embryonic stem cell, Induced pluripotent stem cell, Transcription factor and Reprogramming. Specifically, his work in Cell biology is concerned with the study of Stem cell. His Stem cell study integrates concerns from other disciplines, such as Germ layer and MAPK/ERK pathway.

His research in Embryonic stem cell is mostly focused on Rex1. His research integrates issues of SOX2, Evolutionary biology, Function and G protein in his study of Induced pluripotent stem cell. His Transcription factor research includes themes of Regulation of gene expression, Mitosis, Retinoic acid and Germ cell.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells.

Hitoshi Niwa;Jun-ichi Miyazaki;Austin G. Smith.
Nature Genetics (2000)

4423 Citations

Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4

Jennifer Nichols;Branko Zevnik;Konstantinos Anastassiadis;Hitoshi Niwa.
Cell (1998)

4118 Citations

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

Hitoshi Niwa;Tom Burdon;Ian Chambers;Austin G Smith.
Genes & Development (1998)

1889 Citations

Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells

Shinji Masui;Yuhki Nakatake;Yayoi Toyooka;Daisuke Shimosato.
Nature Cell Biology (2007)

1519 Citations

Interaction between Oct3/4 and Cdx2 Determines Trophectoderm Differentiation

Hitoshi Niwa;Yayoi Toyooka;Daisuke Shimosato;Dan Strumpf.
Cell (2005)

1332 Citations

How is pluripotency determined and maintained

Hitoshi Niwa.
Development (2007)

1118 Citations

A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells

Hitoshi Niwa;Kazuya Ogawa;Daisuke Shimosato;Kenjiro Adachi.
Nature (2009)

950 Citations

The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass.

Noriyuki Nishioka;Ken ichi Inoue;Kenjiro Adachi;Hiroshi Kiyonari.
Developmental Cell (2009)

946 Citations

Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2.

Martha Hotz Vitaterna;Christopher P. Selby;Takeshi Todo;Hitoshi Niwa.
Proceedings of the National Academy of Sciences of the United States of America (1999)

802 Citations

Genome analysis of the platypus reveals unique signatures of evolution

Wesley C. Warren;La Deana W. Hillier;Jennifer A. Marshall Graves;Ewan Birney.
Nature (2008)

765 Citations

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