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Molecular Biology

D-Index
78
Citations
23642
World Ranking
1074
National Ranking
86

Overview

Benjamin D. Simons is affiliated with the University of Cambridge in the United Kingdom. Their research spans the fields of Biochemistry, Genetics and Molecular Biology as well as Medicine. Within these main fields, their work touches on subfields such as Molecular Biology, Cell Biology, Oncology, Genetics, and Surgery.

The scientist focuses on several main topics throughout their research career, including Single-cell and spatial transcriptomics, Cancer Cells and Metastasis, Cellular Mechanics and Interactions, Neurogenesis and neuroplasticity mechanisms, Pluripotent Stem Cells Research, Glioma Diagnosis and Treatment, and RNA Research and Splicing.

Benjamin D. Simons has authored multiple recent papers, with notable publications including:

  • Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis, 2021, Nature Biotechnology
  • A cellular hierarchy in melanoma uncouples growth and metastasis, 2022, Nature
  • Mechanisms of stretch-mediated skin expansion at single-cell resolution, 2020, Nature
  • Cancers make their own luck: theories of cancer origins, 2023, Nature reviews. Cancer
  • Early stem cell aging in the mature brain, 2021, Cell stem cell

The scientist frequently collaborates with other researchers such as Ignacio Bordeu, Seungmin Han, Cédric Blanpain, David J. Jörg, and Bon-Kyoung Koo, with multiple joint publications to their credit.

Their work has been published prominently across several venues. Among the most common are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Nature Communications
  • Cell stem cell
  • Developmental Cell

In addition to journal publications, Benjamin D. Simons has contributed to book literature, notably with the title "Condensed Matter Field Theory" published in 2023 by Cambridge University Press.

Best Publications

  • Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells

    Hugo J. Snippert;Laurens G. van der Flier;Toshiro Sato;Johan H. van Es

  • A single type of progenitor cell maintains normal epidermis

    Elizabeth Clayton;David P. Doupé;Allon M. Klein;Douglas J. Winton

  • Defining the mode of tumour growth by clonal analysis

    Gregory Driessens;Benjamin Beck;Amélie Caauwe;Benjamin D. Simons

  • A single-cell molecular map of mouse gastrulation and early organogenesis.

    Blanca Pijuan-Sala;Jonathan A. Griffiths;Carolina Guibentif;Tom W. Hiscock

  • Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium

    Margherita Y Turco;Lucy Gardner;Jasmine Hughes;Tereza Cindrova-Davies

  • Intestinal Stem Cell Replacement Follows a Pattern of Neutral Drift

    Carlos Lopez-Garcia;Allon M. Klein;Benjamin D. Simons;Douglas J. Winton

  • Distinct contribution of stem and progenitor cells to epidermal maintenance

    Guilhem Mascré;Sophie Dekoninck;Benjamin Drogat;Khalil Kass Youssef

  • Strategies for Homeostatic Stem Cell Self-Renewal in Adult Tissues

    Benjamin D. Simons;Hans Clevers

  • Intestinal crypt homeostasis revealed at single stem cell level by in vivo live-imaging

    Laila Ritsma;Saskia I J Ellenbroek;Anoek Zomer;Hugo J Snippert

  • Deterministic Progenitor Behavior and Unitary Production of Neurons in the Neocortex

    Peng Gao;Maria Pia Postiglione;Teresa G. Krieger;Luisirene Hernandez;Luisirene Hernandez

  • Extensive Proliferation of a Subset of Differentiated, yet Plastic, Medial Vascular Smooth Muscle Cells Contributes to Neointimal Formation in Mouse Injury and Atherosclerosis Models.

    Joel Chappell;Jennifer L. Harman;Vagheesh M. Narasimhan;Haixiang Yu

  • Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy

    Xiaoyang Lan;David J. Jörg;Florence M. G. Cavalli;Laura M. Richards;Laura M. Richards

  • Universal patterns of stem cell fate in cycling adult tissues.

    Allon M. Klein;Allon M. Klein;Benjamin D. Simons

  • Unravelling stem cell dynamics by lineage tracing

    Cédric Blanpain;Benjamin D. Simons;Benjamin D. Simons

  • Defining stem cell dynamics and migration during wound healing in mouse skin epidermis.

    Mariaceleste Aragona;Sophie Dekoninck;Steffen Rulands;Sandrine Lenglez

  • A Single Progenitor Population Switches Behavior to Maintain and Repair Esophageal Epithelium

    David P. Doupé;Maria P. Alcolea;Amit Roshan;Gen Zhang

  • Live imaging of neurogenesis in the adult mouse hippocampus

    Gregor-Alexander Pilz;Sara Bottes;Marion Betizeau;Marion Betizeau;David Josef Jörg;David Josef Jörg

  • 2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size

    Tomoki Otani;Maria C. Marchetto;Fred H. Gage;Benjamin D. Simons

  • Early lineage restriction in temporally distinct populations of Mesp1 progenitors during mammalian heart development

    Fabienne Lescroart;Samira Chabab;Xionghui Lin;Steffen Rulands

  • Mouse Spermatogenic Stem Cells Continually Interconvert between Equipotent Singly Isolated and Syncytial States

    Kenshiro Hara;Toshinori Nakagawa;Hideki Enomoto;Mikiko Suzuki

Frequent Co-Authors

John C. Marioni
John C. Marioni European Bioinformatics Institute
Allon M. Klein
Allon M. Klein Harvard University
Shosei Yoshida
Shosei Yoshida The Graduate University for Advanced Studies, SOKENDAI
Peter B. Littlewood
Peter B. Littlewood University of Chicago
Cédric Blanpain
Cédric Blanpain Université Libre de Bruxelles
Berthold Göttgens
Berthold Göttgens University of Cambridge
Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Trevor A. Graham
Trevor A. Graham Institute of Cancer Research
Nicholas A. Wright
Nicholas A. Wright Queen Mary University of London

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