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An Zwijsen

An Zwijsen

D-Index & Metrics

Molecular Biology

D-Index
41
Citations
7484
World Ranking
3055
National Ranking
40

Overview

An Zwijsen is a researcher affiliated with KU Leuven in Belgium, contributing extensively to the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work spans several subfields including Molecular Biology, Cell Biology, Epidemiology, Physiology, and Cardiology and Cardiovascular Medicine.

The scientist's research covers a diverse range of topics, with substantial focus areas including:

  • Congenital heart defects research
  • Pluripotent Stem Cells Research
  • Renal and related cancers
  • Angiogenesis and VEGF in Cancer
  • CRISPR and Genetic Engineering
  • TGF-β signaling in diseases
  • Alzheimer's disease research and treatments

An Zwijsen has authored and co-authored numerous papers, with recent significant publications such as:

  • "Endothelial Zeb2 preserves the hepatic angioarchitecture and protects against liver fibrosis," 2021, Cardiovascular Research
  • "Impaired SMAD1/5 Mechanotransduction and Cx37 (Connexin37) Expression Enable Pathological Vessel Enlargement and Shunting," 2020, Arteriosclerosis Thrombosis and Vascular Biology
  • "BMP-SMAD1/5 Signaling Regulates Retinal Vascular Development," 2020, Biomolecules
  • "The development of the amnion in mice and other amniotes," 2022, Philosophical Transactions of the Royal Society B Biological Sciences
  • "Prdm16 Supports Arterial Flow Recovery by Maintaining Endothelial Function," 2021, Circulation Research

They have frequently published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cardiovascular Research
  • Journal of Biological Chemistry
  • Scientific Reports
  • Philosophical Transactions of the Royal Society B Biological Sciences

Collaboration forms a notable part of An Zwijsen's work, with repeated co-authorship observed with several researchers, including:

  • Aernout Luttun
  • Elizabeth A. V. Jones
  • Wouter Dheedene
  • Marleen Lox
  • Danny Huylebroeck

Best Publications

  • Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

    An Herreman;Dieter Hartmann;Wim Annaert;Paul Saftig

  • Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects

    H Chang;Danny Huylebroeck;K Verschueren;Qiuxia Guo

  • Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3

    Vinciane Gaussin;Tom Van de Putte;Yuji Mishina;Mark C. Hanks

  • Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing.

    Saskia Lippens;M Kockx;M Knaapen;L Mortier

  • Stalk Cell Phenotype Depends on Integration of Notch and Smad1/5 Signaling Cascades

    Iván M. Moya;Lieve Umans;Elke Maas;Paulo N.G. Pereira

  • Conditional Deletion of Smad1 and Smad5 in Somatic Cells of Male and Female Gonads Leads to Metastatic Tumor Development in Mice

    Stephanie A. Pangas;Xiaohui Li;Lieve Umans;An Zwijsen

  • Differential contribution of the three Aph1 genes to γ-secretase activity in vivo

    Lutgarde Serneels;Tim Dejaegere;Kathleen Craessaerts;Katrien Horré

  • Smad5 is essential for left-right asymmetry in mice

    Hua Chang;An Zwijsen;Hannes Vogel;Danny Huylebroeck

  • The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGFβ/BMP and hypoxia pathways

    Tilman Borggrefe;Matthias Lauth;An Zwijsen;Danny Huylebroeck

  • Alk3/Bmpr1a Receptor Is Required for Development of the Atrioventricular Canal Into Valves and Annulus Fibrosus

    Vinciane Gaussin;Gregory E. Morley;Luk Cox;An Zwijsen

  • On the origin of amniotic stem cells: of mice and men.

    P Mariya Dobreva;Paulo Nelson Gomes Pereira;Jan Deprest;An Zwijsen

  • New intracellular components of bone morphogenetic protein/Smad signaling cascades.

    An Zwijsen;Kristin Verschueren;Danny Huylebroeck

  • BMP signaling in vascular biology and dysfunction

    Amaya Garci­a de Vinuesa;Salim Abdelilah-Seyfried;Salim Abdelilah-Seyfried;Petra Knaus;An Zwijsen

  • Transforming growth factor-beta signalling in extraembryonic mesoderm is required for yolk sac vasculogenesis in mice.

    MJ Goumans;An Zwijsen;MA van Rooijen;Danny Huylebroeck

  • Zeb2 recruits HDAC–NuRD to inhibit Notch and controls Schwann cell differentiation and remyelination

    Lai Man Natalie Wu;Jincheng Wang;Jincheng Wang;Andrea Conidi;Chuntao Zhao

  • Slowed Conduction and Thin Myelination of Peripheral Nerves Associated with Mutant Rho Guanine-Nucleotide Exchange Factor 10

    Kristien Verhoeven;Peter De Jonghe;Tom Van de Putte;Eva Nelis

  • Bone Morphogenetic Proteins in Vascular Homeostasis and Disease.

    Marie-José Goumans;An Zwijsen;Peter ten Dijke;Sabine Bailly;Sabine Bailly;Sabine Bailly

  • Functional Redundancy of TGF-beta Family Type I Receptors and Receptor-Smads in Mediating Anti-Müllerian Hormone-Induced Müllerian Duct Regression in the Mouse

    G. D Orvis;S. P Jamin;S. P Jamin;K. M Kwan;K. M Kwan;Y Mishina

  • Fetal mesenchymal stem cells: isolation, properties and potential use in perinatology and regenerative medicine

    L Gucciardo;R Lories;N Ochsenbein-Kölble;E Done

  • Few Smad proteins and many Smad-interacting proteins yield multiple functions and action modes in TGFβ/BMP signaling in vivo

    Andrea Conidi;Andrea Conidi;Silvia Cazzola;Silvia Cazzola;Karen Beets;Kathleen Coddens;Kathleen Coddens

Frequent Co-Authors

Susana Lopes
Susana Lopes Leiden University Medical Center
Christine L. Mummery
Christine L. Mummery Leiden University Medical Center
Marie-José Goumans
Marie-José Goumans Leiden University Medical Center
Sabine Bailly
Sabine Bailly Grenoble Alpes University
Yuji Mishina
Yuji Mishina University of Michigan–Ann Arbor
Michael D. Schneider
Michael D. Schneider Imperial College London
Vesa Kaartinen
Vesa Kaartinen University of Michigan–Ann Arbor
Anita B. Roberts
Anita B. Roberts National Institutes of Health

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