World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
70
Citations
23518
World Ranking
1403
National Ranking
108

Overview

Ludovic Vallier is affiliated with the University of Cambridge in the United Kingdom. Their research spans multiple intersecting domains within medicine and biochemistry, genetics, and molecular biology.

Their recent scholarly output includes significant publications such as:

  • Single-cell transcriptomic characterization of a gastrulating human embryo (2021, Nature)
  • Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression (2020, Nature Communications)
  • Cholangiocyte organoids can repair bile ducts after transplantation in the human liver (2021, Science)
  • Single-Cell Sequencing of Developing Human Gut Reveals Transcriptional Links to Childhood Crohn's Disease (2020, Developmental Cell)
  • FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2 (2022, Nature)

Their frequent co-authors include:

  • Kourosh Saeb-Parsy
  • Daniel Ortmann
  • Daniele Muraro
  • Carola Maria Morell
  • José Garcia-Bernardo

Key publication venues where Ludovic Vallier regularly contributes are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Hepatology
  • Stem Cell Reports
  • Nature
  • Developmental Cell

Their main fields of study include medicine and biochemistry, genetics and molecular biology. Within those, subfields they have contributed to are molecular biology, surgery, hepatology, epidemiology, and genetics.

Research topics that dominate their work encompass:

  • Liver physiology and pathology
  • Pluripotent Stem Cells Research
  • Pancreatic function and diabetes
  • CRISPR and Genetic Engineering
  • Single-cell and spatial transcriptomics
  • Tissue Engineering and Regenerative Medicine
  • Liver Disease Diagnosis and Treatment

Best Publications

  • Derivation of pluripotent epiblast stem cells from mammalian embryos

    I. Gabrielle M. Brons;Lucy E. Smithers;Matthew W. B. Trotter;Peter Rugg-Gunn

  • Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells.

    Ludovic Vallier;Morgan Alexander;Roger A. Pedersen

  • Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

    Kosuke Yusa;S. Tamir Rashid;Helene Strick-Marchand;Helene Strick-Marchand;Ignacio Varela

  • Senescence impairs successful reprogramming to pluripotent stem cells

    Ana Banito;Sheikh T. Rashid;Juan Carlos Acosta;Si De Li

  • Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells

    S. Tamir Rashid;Sebastien Corbineau;Nick Hannan;Stefan J. Marciniak

  • Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development

    Thomas Touboul;Nicholas R F Hannan;Sébastien Corbineau;Amélie Martinez

  • Common genetic variation drives molecular heterogeneity in human iPSCs

    Helena Kilpinen;Angela Goncalves;Andreas Leha;Vackar Afzal

  • The Cell-Cycle State of Stem Cells Determines Cell Fate Propensity

    Siim Pauklin;Ludovic Vallier;Ludovic Vallier

  • Activin/Nodal signalling maintains pluripotency by controlling Nanog expression

    Ludovic Vallier;Sasha Mendjan;Stephanie Brown;Zhenzhi Chng

  • Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway

    Ludovic Vallier;Daniel Reynolds;Roger A. Pedersen

  • GDF15 mediates the effects of metformin on body weight and energy balance

    Anthony P. Coll;Michael Chen;Pranali Taskar;Debra Rimmington

  • Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation

    Fotios Sampaziotis;Fotios Sampaziotis;Miguel Cardoso de Brito;Pedro Madrigal;Pedro Madrigal;Alessandro Bertero

  • Genome editing reveals a role for OCT4 in human embryogenesis

    Norah M. E. Fogarty;Afshan McCarthy;Kirsten E. Snijders;Benjamin E. Powell

  • Pluripotency factors regulate definitive endoderm specification through eomesodermin

    Adrian Kee Keong Teo;Sebastian J. Arnold;Matthew W.B. Trotter;Stephanie Brown

  • Transplantation of Expanded Fetal Intestinal Progenitors Contributes to Colon Regeneration after Injury

    Robert P. Fordham;Shiro Yui;Shiro Yui;Nicholas R.F. Hannan;Christoffer Soendergaard

  • Inhibition of Activin/Nodal signaling promotes specification of human embryonic stem cells into neuroectoderm.

    Joseph R. Smith;Ludovic Vallier;Giuseppe Lupo;Morgan Alexander

  • Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes

    Melissa Baxter;Sarah Withey;Sean Harrison;Charis-Patricia Segeritz;Charis-Patricia Segeritz

  • Production of hepatocyte-like cells from human pluripotent stem cells

    Nicholas R F Hannan;Charis-Patricia Segeritz;Thomas Touboul;Ludovic Vallier;Ludovic Vallier

  • Early Cell Fate Decisions of Human Embryonic Stem Cells and Mouse Epiblast Stem Cells Are Controlled by the Same Signalling Pathways

    Ludovic Vallier;Thomas Touboul;Thomas Touboul;Zhenzhi Chng;Minodora Brimpari

  • Genetic background drives transcriptional variation in human induced pluripotent stem cells.

    Foad Rouhani;Natsuhiko Kumasaka;Miguel Cardoso de Brito;Allan Bradley

Frequent Co-Authors

Roger A. Pedersen
Roger A. Pedersen University of Cambridge
Oliver Stegle
Oliver Stegle German Cancer Research Center
John C. Marioni
John C. Marioni European Bioinformatics Institute
Graeme J. M. Alexander
Graeme J. M. Alexander University College London
David A. Lomas
David A. Lomas University College London
Marc Jan Bonder
Marc Jan Bonder University of Groningen
Neil A. Hanley
Neil A. Hanley University of Manchester
Daniel J. Gaffney
Daniel J. Gaffney Wellcome Sanger Institute
Sarah A. Teichmann
Sarah A. Teichmann University of Cambridge
Willem H. Ouwehand
Willem H. Ouwehand University of Cambridge

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a degree in Molecular Biology opens the door to many related online programs and career pathways in the broader field of health, science, and human services. For example, students with a science background may be interested in the best online msw programs, which prepare graduates for impactful work in social and healthcare settings.

If you are interested in the psychology aspect of molecular biology, such as how brain chemistry influences behavior, consider options like fast track masters in psychology. These programs are designed for those seeking accelerated paths to advanced credentials and expertise in mental health.

For those focused on counseling or mental health services, online clinical mental health counseling programs provide convenient access to advanced training and can align well with a scientific background.

Finally, if you have a military background or require extra support as a service member or veteran, consider the best military friendly colleges as you plan your educational journey. Flexible online learning can help you transition to a variety of roles in molecular biology and its allied fields.

Best Scientists Citing Ludovic Vallier

Trending Scientists

Recently Published Articles