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Biology and Biochemistry

D-Index
86
Citations
39404
World Ranking
2915
National Ranking
215

Overview

Arndt Borkhardt is affiliated with Heinrich Heine University Düsseldorf in Germany and has a research profile focusing on medicine, biochemistry, genetics, and molecular biology. Their publication record includes extensive work in molecular biology, public health, environmental and occupational health, oncology, genetics, and immunology.

Their research topics encompass acute lymphoblastic leukemia research, childhood cancer survivors' quality of life, histone deacetylase inhibitors research, CAR-T cell therapy research, acute myeloid leukemia research, protein degradation and inhibitors, and chronic myeloid leukemia treatments.

Among recent papers authored or co-authored by Borkhardt are the following:

  • The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets, 2021, Cancer Discovery
  • Flash survey on severe acute respiratory syndrome coronavirus-2 infections in paediatric patients on anticancer treatment, 2020, European Journal of Cancer
  • Induction of trained immunity by influenza vaccination - impact on COVID-19, 2021, PLoS Pathogens
  • The genomic and transcriptional landscape of primary central nervous system lymphoma, 2022, Nature Communications
  • An intact gut microbiome protects genetically predisposed mice against leukemia, 2020, Blood

Borkhardt frequently publishes in the following venues:

  • Blood
  • HemaSphere
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Leukemia
  • International Journal of Cancer

Frequent collaborators include:

  • Ute Fischer
  • Sanil Bhatia
  • Triantafyllia Brozou
  • Julia Hauer
  • Rabea Wagener

Best Publications

  • A mammalian microRNA expression atlas based on small RNA library sequencing.

    Pablo Landgraf;Mirabela Rusu;Robert Sheridan;Alain Sewer;Alain Sewer

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

    Salima Hacein-Bey-Abina;Alexandrine Garrigue;Gary P. Wang;Jean Soulier

  • The landscape of genomic alterations across childhood cancers

    Susanne N. Gröbner;Barbara C. Worst;Joachim Weischenfeldt;Joachim Weischenfeldt;Ivo Buchhalter

  • New microRNAs from mouse and human

    Mariana Lagos-Quintana;Reinhard Rauhut;Jutta Meyer;Arndt Borkhardt

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma.

    Markus Metzler;Monika Wilda;Kerstin Busch;Susanne Viehmann

  • Backtracking leukemia to birth: Identification of clonotypic gene fusion sequences in neonatal blood spots

    Karin B. Gale;Anthony M. Ford;Reinald Repp;Arndt Borkhardt

  • Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi).

    Monika Wilda;Uta Fuchs;Wilhelm Wössmann;Arndt Borkhardt

  • Phase I/Phase II Study of Blinatumomab in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia

    Arend von Stackelberg;Franco Locatelli;Gerhard Zugmaier;Rupert Handgretinger

  • Small interfering RNAs: a revolutionary tool for the analysis of gene function and gene therapy.

    Thomas Tuschl;Arndt Borkhardt

  • Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

    Julia Richter;Matthias Schlesner;Steve Hoffmann;Markus Kreuz

  • Prognostic Value of Minimal Residual Disease Quantification Before Allogeneic Stem-Cell Transplantation in Relapsed Childhood Acute Lymphoblastic Leukemia: The ALL-REZ BFM Study Group

    Peter Bader;Hermann Kreyenberg;Günter H.R. Henze;Cornelia Eckert

  • Prednisone response is the strongest predictor of treatment outcome in infant acute lymphoblastic leukemia.

    Michael Dördelmann;Alfred Reiter;Arndt Borkhardt;Wolf-Dieter Ludwig

  • Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing

    Volker Hovestadt;David T.W. Jones;Simone Picelli;Wei Wang

  • Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization.

    Bernd B. Zeisig;Tom Milne;María Paz García-Cuéllar;Silke Schreiner

  • Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome

    Dani Bercovich;Ithamar Ganmore;Linda M. Scott;Gilad Wainreb

  • Incidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the German and Italian multicenter therapy trials

    Arndt Borkhardt;Giovanni Cazzaniga;Susanne Viehmann;Maria Grazia Valsecchi

  • RNA targets of wild-type and mutant FET family proteins

    Jessica I Hoell;Erik Larsson;Simon Runge;Jeffrey D Nusbaum

  • Molecular basis of the spectral expression of CIAS1 mutations associated with phagocytic cell-mediated autoinflammatory disorders CINCA/NOMID, MWS, and FCU.

    Bénédicte Neven;Isabelle Callebaut;Anne-Marie Prieur;Jérôme Feldmann

Frequent Co-Authors

Jochen Harbott
Jochen Harbott University of Giessen
Marc Remke
Marc Remke German Cancer Research Center
Martin Schrappe
Martin Schrappe Kiel University
Guido Reifenberger
Guido Reifenberger Heinrich Heine University Düsseldorf
Oskar A. Haas
Oskar A. Haas Medical University of Vienna
Thomas Klingebiel
Thomas Klingebiel Goethe University Frankfurt
Martin Stanulla
Martin Stanulla Hannover Medical School
Peter Bader
Peter Bader Goethe University Frankfurt
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
Isidro Sánchez-García
Isidro Sánchez-García University of Salamanca

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