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Raquel Hontecillas

Raquel Hontecillas

D-Index & Metrics

Immunology

D-Index
51
Citations
8450
World Ranking
4161
National Ranking
1899

Overview

Raquel Hontecillas is affiliated with Virginia Tech in the United States. Their research spans multiple fields primarily focused on medicine and biochemistry, genetics, and molecular biology. Within these areas, they have contributed extensively to subfields such as immunology, molecular biology, infectious diseases, epidemiology, and genetics.

Their scientific work addresses several key topics, including:

  • Inflammatory Bowel Disease
  • Microscopic Colitis
  • Helicobacter pylori-related gastroenterology studies
  • Clostridium difficile and Clostridium perfringens research
  • Immune Cell Function and Interaction
  • Gut microbiota and health
  • Gastrointestinal motility and disorders

Their publication record includes contributions to various scientific journals. The most frequent venues for their research publications are:

  • The Journal of Immunology
  • Scientific Reports
  • Inflammatory Bowel Diseases
  • The American Journal of Gastroenterology
  • Gastroenterology

Raquel Hontecillas has co-authored many works with several frequent collaborators, including:

  • Josep Bassaganya-Riera
  • Nuria Tubau-Juni
  • Andrew Leber
  • Andrew B. Leber
  • Sameeksha S. Alva

Notable recent papers authored or co-authored by Raquel Hontecillas include:

  • Malnutrition, Health and the Role of Machine Learning in Clinical Setting (2020, Frontiers in Nutrition)
  • Abscisic acid enriched fig extract promotes insulin sensitivity by decreasing systemic inflammation and activating LANCL2 in skeletal muscle (2020, Scientific Reports)
  • NLRX1 is a key regulator of immune signaling during invasive pulmonary aspergillosis (2020, PLoS Pathogens)
  • Enemy of My Enemy: A Novel Insect-Specific Flavivirus Offers a Promising Platform for a Zika Virus Vaccine (2021, Vaccines)
  • Identification of new regulatory genes through expression pattern analysis of a global RNA-seq dataset from a Helicobacter pylori co-culture system (2020, Scientific Reports)

Best Publications

  • Activation of PPAR γ and δ by conjugated linoleic acid mediates protection from experimental inflammatory bowel disease

    Josep Bassaganya-Riera;Kathryn Reynolds;Susan Martino-Catt;Yongzhi Cui

  • CLA and n-3 PUFA differentially modulate clinical activity and colonic PPAR-responsive gene expression in a pig model of experimental IBD.

    Josep Bassaganya-Riera;Raquel Hontecillas;Raquel Hontecillas

  • Peroxisome Proliferator-Activated Receptor γ Is Required for Regulatory CD4+ T Cell-Mediated Protection against Colitis

    Raquel Hontecillas;Josep Bassaganya-Riera

  • Nutritional Regulation of Porcine Bacterial-Induced Colitis by Conjugated Linoleic Acid

    Raquel Hontecillas;Michael J. Wannemeulher;Dean R. Zimmerman;David L. Hutto

  • Dietary abscisic acid ameliorates glucose tolerance and obesity-related inflammation in db/db mice fed high-fat diets.

    Amir J. Guri;Raquel Hontecillas;Hongwei Si;Dongmin Liu

  • Activation of PPAR gamma and alpha by punicic acid ameliorates glucose tolerance and suppresses obesity-related inflammation.

    Raquel Hontecillas;Marianne O'Shea;Alexandra Einerhand;Margaret Diguardo

  • Modulation of inflammation and immunity by dietary conjugated linoleic acid

    Monica Viladomiu;Raquel Hontecillas;Josep Bassaganya-Riera

  • Nutritional protective mechanisms against gut inflammation

    Monica Viladomiu;Raquel Hontecillas;Lijuan Yuan;Pinyi Lu

  • Abscisic Acid Regulates Inflammation via Ligand-binding Domain-independent Activation of Peroxisome Proliferator-activated Receptor γ *

    Josep Bassaganya-Riera;Amir J. Guri;Pinyi Lu;Montse Climent

  • Conjugated Linoleic Acid Ameliorates Inflammation-Induced Colorectal Cancer in Mice through Activation of PPARγ

    Nicholas P. Evans;Sarah A. Misyak;Eva M. Schmelz;Amir J. Guri

  • Conjugated Linoleic Acid Ameliorates Viral Infectivity in a Pig Model of Virally Induced Immunosuppression

    Josep Bassaganya-Riera;Roman M. Pogranichniy;Scott C. Jobgen;Pat G. Halbur

  • Immunoregulatory Mechanisms Underlying Prevention of Colitis-Associated Colorectal Cancer by Probiotic Bacteria

    Josep Bassaganya-Riera;Monica Viladomiu;Mireia Pedragosa;Claudio De Simone

  • Dietary conjugated linoleic acid and n-3 polyunsaturated fatty acids in inflammatory bowel disease.

    Josep Bassaganya-Riera;Raquel Hontecillas

  • Loss of PPARγ in immune cells impairs the ability of abscisic acid to improve insulin sensitivity by suppressing monocyte chemoattractant protein-1 expression and macrophage infiltration into white adipose tissue

    Amir J. Guri;Raquel Hontecillas;Gerardo Ferrer;Oriol Casagran

  • PPAR γ is highly expressed in F4/80hi adipose tissue macrophages and dampens adipose-tissue inflammation

    Josep Bassaganya-Riera;Sarah Misyak;Amir J. Guri;Raquel Hontecillas

  • Conjugated linoleic acid modulates immune responses in patients with mild to moderately active Crohn's disease.

    Josep Bassaganya-Riera;Raquel Hontecillas;William T. Horne;Mikki Sandridge

  • The Role of T cell PPAR γ in mice with experimental inflammatory bowel disease

    Amir J Guri;Saroj K Mohapatra;William T Horne;Raquel Hontecillas

  • Dietary Conjugated Linoleic Acid Modulates Phenotype and Effector Functions of Porcine CD8+ Lymphocytes

    Josep Bassaganya-Riera;Raquel Hontecillas;Dean R. Zimmerman;Michael J. Wannemuehler

  • Immunoregulatory mechanisms of macrophage PPAR-γ in mice with experimental inflammatory bowel disease

    Raquel Hontecillas;William T. Horne;Montse Climent;Amir J. Guri

  • Systems Modeling of Molecular Mechanisms Controlling Cytokine-driven CD4+ T Cell Differentiation and Phenotype Plasticity

    Adria Carbo;Raquel Hontecillas;Barbara Kronsteiner;Monica Viladomiu

  • Model of colonic inflammation: immune modulatory mechanisms in inflammatory bowel disease.

    Katherine Wendelsdorf;Josep Bassaganya-Riera;Raquel Hontecillas;Stephen Eubank

  • Soluble Fibers and Resistant Starch Ameliorate Disease Activity in Interleukin-10–Deficient Mice with Inflammatory Bowel Disease

    Josep Bassaganya-Riera;Margaret DiGuardo;Monica Viladomiu;Anibal de Horna

  • Abscisic acid ameliorates experimental IBD by downregulating cellular adhesion molecule expression and suppressing immune cell infiltration

    Amir J. Guri;Raquel Hontecillas;Josep Bassaganya-Riera

  • Systems Modeling of the Role of Interleukin-21 in the Maintenance of Effector CD4+ T Cell Responses during Chronic Helicobacter pylori Infection

    Adria Carbo;Danyvid Olivares-Villagómez;Raquel Hontecillas;Josep Bassaganya-Riera

Frequent Co-Authors

Bruno W. S. Sobral
Bruno W. S. Sobral Virginia Tech
Richard L. Guerrant
Richard L. Guerrant University of Virginia
Madhav V. Marathe
Madhav V. Marathe University of Virginia
Stephen E. Girardin
Stephen E. Girardin University of Toronto
Paul S. Hoffman
Paul S. Hoffman University of Virginia
Pierre J. Magistretti
Pierre J. Magistretti École Polytechnique Fédérale de Lausanne
Hans H Herfarth
Hans H Herfarth University of North Carolina at Chapel Hill
Louis M. Havekes
Louis M. Havekes Leiden University Medical Center
David S. Liebeskind
David S. Liebeskind University of California, Los Angeles

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