William J. Murphy

Overview

Best Publications

• Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide

  Charles J. Lowenstein;Evan W. Alley;Prafulla Raval;Adele M. Snowman

  1364
  Citations

• Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression.

  Rosalba Salcedo;Maria Lourdes Ponce;Howard A. Young;Ken Wasserman

  1136
  Citations

• Advances in graft-versus-host disease biology and therapy

  Bruce R. Blazar;William J. Murphy;Mehrdad Abedi

  1080
  Citations

• Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide.

  R B Lorsbach;W J Murphy;C J Lowenstein;S H Snyder

  917
  Citations

• Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade

  Ziming Wang;Ethan G. Aguilar;Jesus I. Luna;Cordelia Dunai

  819
  Citations

• Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia

  Qing Zhou;Meghan E. Munger;Rachelle G. Veenstra;Brenda J. Weigel

  792
  Citations

• Identification of Defensin-1, Defensin-2, and CAP37/Azurocidin as T-cell Chemoattractant Proteins Released from Interleukin-8-stimulated Neutrophils (∗)

  Oleg Chertov;Dennis F. Michiel;Luoling Xu;Ji Ming Wang

  730
  Citations

• Immunobiology of Allogeneic Hematopoietic Stem Cell Transplantation

  Lisbeth A. Welniak;Bruce R. Blazar;William J. Murphy

  665
  Citations

• Serum amyloid A is a chemoattractant: induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes.

  Raffaele Badolato;Ji Ming Wang;William J Murphy;Andrew R. Lloyd

  644
  Citations

• Monocyte chemotactic protein-1 (MCP-1), -2, and -3 are chemotactic for human T lymphocytes.

  D. D. Taub;P. Proost;William J Murphy;M. Anver

  460
  Citations

• Chemokines and T lymphocyte activation: I. Beta chemokines costimulate human T lymphocyte activation in vitro.

  Dennis D. Taub;Susan M. Turcovski-Corrales;Michael L. Key;Dan L. Longo

  386
  Citations

• An Interferon-γ-activated Site (GAS) Is Necessary for Full Expression of the Mouse iNOS Gene in Response to Interferon-γ and Lipopolysaccharide

  Jianjun Gao;David C. Morrison;Tari J. Parmely;Stephen W. Russell

  379
  Citations

• Suppression of graft-versus-host disease and amplification of graft-versus-tumor effects by activated natural killer cells after allogeneic bone marrow transplantation.

  Osamu Asai;Dan L. Longo;Zhi Gang Tian;Ronald L. Hornung

  362
  Citations

• T lymphocyte recruitment by interleukin-8 (IL-8). IL-8-induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo.

  Dennis D. Taub;Miriam Anver;Joost J. Oppenheim;Dan L. Longo

  361
  Citations

• 'Unlicensed' natural killer cells dominate the response to cytomegalovirus infection

  Mark T Orr;William J Murphy;Lewis L Lanier

  342
  Citations

• Identification of Human Neutrophil-derived Cathepsin G and Azurocidin/CAP37 as Chemoattractants for Mononuclear Cells and Neutrophils

  Oleg Chertov;Hirotsugu Ueda;Luo Ling Xu;Kenji Tani

  339
  Citations

• Eotaxin (CCL11) Induces In Vivo Angiogenic Responses by Human CCR3+ Endothelial Cells

  R. Salcedo;H. A. Young;M. L. Ponce;J. M. Ward

  334
  Citations

• Canine and Feline Parvoviruses Can Use Human or Feline Transferrin Receptors To Bind, Enter, and Infect Cells

  John S. L. Parker;William J. Murphy;Dai Wang;Stephen J. O'Brien

  333
  Citations

• Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia.

  Qing Zhou;Meghan E. Munger;Steven L. Highfill;Jakub Tolar

  328
  Citations

• Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans

  Mathangi Srinivasan;Ryan Flynn;Andrew Price;Ann Ranger

  324
  Citations

• Rejection of bone marrow allografts by mice with severe combined immune deficiency (SCID). Evidence that natural killer cells can mediate the specificity of marrow graft rejection

  William J Murphy;V. Kumar;M. Bennett

  320
  Citations

• Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib

  Kai Sun;Lisbeth A. Welniak;Angela Panoskaltsis-Mortari;Matthew J. O'Shaughnessy

  314
  Citations

• Ganciclovir Treatment of Herpes Simplex Thymidine Kinase-Transduced Primary T Lymphocytes: An Approach for Specific In Vivo Donor T-cell Depletion After Bone Marrow Transplantation?

  P Tiberghien;CW Reynolds;J Keller;S Spence

  314
  Citations