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Paul S. Hoffman

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
8639
World Ranking
15798
National Ranking
6572

Paul S. Hoffman publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Paul S. Hoffman sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 136 publications — 20th percentile

20% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Paul S. Hoffman D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Paul S. Hoffman sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 54 D-Index — 22nd percentile

22% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Paul S. Hoffman is affiliated with the University of Virginia in the United States. Their research encompasses multiple fields of study, including Biochemistry, Genetics and Molecular Biology, Medicine, and Dentistry. The scientist has contributed notably to subfields such as Molecular Biology, Periodontics, Public Health, Environmental and Occupational Health, Infectious Diseases, and Materials Chemistry.

Their work addresses several main topics, including:

  • Oral microbiology and periodontitis research
  • Oral Health Pathology and Treatment
  • HIV/AIDS oral health manifestations
  • Clostridium difficile and Clostridium perfringens research
  • Enzyme Structure and Function
  • Porphyrin Metabolism and Disorders
  • Antibiotic Resistance in Bacteria

Paul S. Hoffman has published in various scientific venues. Frequent venues for their publications include:

  • Journal of Oral Biosciences
  • Antibiotics
  • Cell Reports Medicine
  • Frontiers in Oral Health
  • British Journal of Gastroenterology

Some of their recent papers are:

  • Antibacterial Discovery: 21st Century Challenges, 2020, Antibiotics
  • Amixicile: A Concept Therapeutic for Treatment of Chronic Anaerobic Infections, 2020, British Journal of Gastroenterology

They have collaborated frequently with several co-authors, including:

  • Qin Gui
  • Janina P. Lewis
  • Andrea M. Gough
  • Anita C. Parker
  • Patricia J. O'Bryan

Best Publications

  • Metronidazole resistance in Helicobacter pylori is due to null mutations in a gene (rdxA) that encodes an oxygen‐insensitive NADPH nitroreductase

    Goodwin A;Kersulyte D;Sisson G;Veldhuyzen van Zanten Sj

  • Surface-associated hsp60 chaperonin of Legionella pneumophila mediates invasion in a HeLa cell model.

    Rafael A. Garduño;Elizabeth Garduño;Paul S. Hoffman

  • Antiparasitic drug nitazoxanide inhibits the pyruvate oxidoreductases of Helicobacter pylori, selected anaerobic bacteria and parasites, and Campylobacter jejuni

    Paul S. Hoffman;Gary Sisson;Matthew A. Croxen;Kevin Welch

  • Essential Thioredoxin-Dependent Peroxiredoxin System from Helicobacter pylori: Genetic and Kinetic Characterization

    Laura M. S. Baker;Ausra Raudonikiene;Paul S. Hoffman;Leslie B. Poole

  • Treatment of intestinal parasitic infections: a review of nitazoxanide

    Herbert M Gilles;Paul S Hoffman

  • The Helicobacter pylori chemotaxis receptor TlpB (HP0103) is required for pH taxis and for colonization of the gastric mucosa.

    Matthew A. Croxen;Gary Sisson;Roberto Melano;Paul S. Hoffman

  • Intracellular Growth of Legionella pneumophila Gives Rise to a Differentiated Form Dissimilar to Stationary-Phase Forms

    Rafael A. Garduño;Elizabeth Garduño;Margot Hiltz;Paul S. Hoffman

  • Enzymes Associated with Reductive Activation and Action of Nitazoxanide, Nitrofurans, and Metronidazole in Helicobacter pylori

    Gary Sisson;Avery Goodwin;Ausra Raudonikiene;Nicky J. Hughes

  • Acidic pH changes receptor binding specificity of Helicobacter pylori: a binary adhesion model in which surface heat shock (stress) proteins mediate sulfatide recognition in gastric colonization.

    M Huesca;S Borgia;P Hoffman;C A Lingwood

  • Systematic Identification of Selective Essential Genes in Helicobacter pylori by Genome Prioritization and Allelic Replacement Mutagenesis

    Alison F. Chalker;Heather W. Minehart;Nicky J. Hughes;Kristin K. Koretke

  • Sequential Inactivation of rdxA (HP0954) and frxA (HP0642) Nitroreductase Genes Causes Moderate and High-Level Metronidazole Resistance in Helicobacter pylori

    Jy Jeong;AK Mukhopadhyay;D Dailidiene;Y Wang

  • Metronidazole activation is mutagenic and causes DNA fragmentation in Helicobacter pylori and in Escherichia coli containing a cloned H. pylori RdxA(+) (Nitroreductase) gene.

    Gary Sisson;Jin-Yong Jeong;Avery Goodwin;Louis Bryden

  • Metabolic activities of metronidazole-sensitive and -resistant strains of Helicobacter pylori: repression of pyruvate oxidoreductase and expression of isocitrate lyase activity correlate with resistance.

    P. S. Hoffman;A. Goodwin;J. Johnsen;K. Magee

  • Immunolocalization of Hsp60 in Legionella pneumophila

    Rafael A. Garduño;Gary Faulkner;Mary A. Trevors;Neeraj Vats

  • Flavodoxin:Quinone Reductase (FqrB): a Redox Partner of Pyruvate:Ferredoxin Oxidoreductase That Reversibly Couples Pyruvate Oxidation to NADPH Production in Helicobacter pylori and Campylobacter jejuni

    Martin St. Maurice;Nunilo Cremades;Matthew A. Croxen;Gary Sisson

  • Persistent G. lamblia impairs growth in a murine malnutrition model.

    Luther A. Bartelt;James Roche;Glynis Kolling;David Bolick

  • Germination and Amplification of Anthrax Spores by Soil-Dwelling Amoebas

    Rafik Dey;Paul S. Hoffman;Ian J. Glomski

  • Elevated levels of Legionella pneumophila stress protein Hsp60 early in infection of human monocytes and L929 cells correlate with virulence.

    R C Fernandez;S M Logan;S H Lee;P S Hoffman

  • Small molecule promotes β-catenin citrullination and inhibits Wnt signaling in cancer.

    Yi Qu;Yi Qu;Yi Qu;Jan Roger Olsen;Xing Yuan;Phil F Cheng

  • Roles of FrxA and RdxA nitroreductases of Helicobacter pylori in susceptibility and resistance to metronidazole.

    Jin-Yong Jeong;Asish K. Mukhopadhyay;Junko K. Akada;Daiva Dailidiene

Frequent Co-Authors

Douglas E. Berg
Douglas E. Berg Washington University in St. Louis
Timothy L. Macdonald
Timothy L. Macdonald University of Virginia
Richard L. Guerrant
Richard L. Guerrant University of Virginia
Costi D. Sifri
Costi D. Sifri University of Virginia
Thomas J. Marrie
Thomas J. Marrie Dalhousie University
Asish Mukhopadhyay
Asish Mukhopadhyay Indian Council of Medical Research
Eric R. Houpt
Eric R. Houpt University of Virginia
Paul H. Edelstein
Paul H. Edelstein University of Pennsylvania
Derrick W. Crook
Derrick W. Crook University of Oxford
Konstantin Severinov
Konstantin Severinov Rutgers, The State University of New Jersey

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Best Scientists Citing Paul S. Hoffman

Douglas E. Berg

Douglas E. Berg

Washington University in St. Louis

Publications: 41

Johannes G. Kusters

Johannes G. Kusters

Utrecht University

Publications: 36

Carmen Buchrieser

Carmen Buchrieser

Institut Pasteur

Publications: 30

Arnoud H. M. van Vliet

Arnoud H. M. van Vliet

University of Surrey

Publications: 26

Francis Mégraud

Francis Mégraud

University of Bordeaux

Publications: 26

Richard L. Guerrant

Richard L. Guerrant

University of Virginia

Publications: 25

Andrew Hemphill

Andrew Hemphill

University of Bern

Publications: 23

David Y. Graham

David Y. Graham

Baylor College of Medicine

Publications: 19

Timothy L. Cover

Timothy L. Cover

Vanderbilt University Medical Center

Publications: 17

Yoshio Yamaoka

Yoshio Yamaoka

Oita University

Publications: 16

Michael Steinert

Michael Steinert

Technische Universität Braunschweig

Publications: 16

David J. Kelly

David J. Kelly

University of Sheffield

Publications: 15

Christina M. J. E. Vandenbroucke-Grauls

Christina M. J. E. Vandenbroucke-Grauls

Vrije Universiteit Amsterdam

Publications: 15

Asish Mukhopadhyay

Asish Mukhopadhyay

Indian Council of Medical Research

Publications: 14

Agnès Labigne

Agnès Labigne

Institut Pasteur

Publications: 14

Norbert Müller

Norbert Müller

University of Bern

Publications: 14

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