World's Best Scientists 2026 revealed!
Timothy L. Macdonald

Timothy L. Macdonald

D-Index & Metrics

Chemistry

D-Index
74
Citations
15984
World Ranking
4828
National Ranking
1513

Biology and Biochemistry

D-Index
74
Citations
15302
World Ranking
5746
National Ranking
2718

Research.com Recognitions

  • 1981 - Fellow of Alfred P. Sloan Foundation

Overview

Timothy L. Macdonald is affiliated with the University of Virginia in the United States. Their research spans multiple disciplines, predominantly within engineering, physics and astronomy, as well as biochemistry, genetics, and molecular biology.

The main fields of study for Macdonald include:

  • Engineering
  • Physics and Astronomy
  • Biochemistry, Genetics and Molecular Biology

More specific subfields covered in their research are:

  • Electrical and Electronic Engineering
  • Atomic and Molecular Physics, and Optics
  • Dermatology
  • Molecular Biology
  • Cell Biology

The research topics they engage with highlight a focus on photonics, semiconductors, and skin-related biological studies. These topics include:

  • Photonic and Optical Devices
  • Advanced Fiber Laser Technologies
  • Semiconductor materials and devices
  • Skin Protection and Aging
  • Bioluminescence and chemiluminescence research
  • Melanin and skin pigmentation
  • Nonlinear Optical Materials Research

Macdonald has published papers in various scientific venues, including:

  • Optical Materials Express
  • Journal of Investigative Dermatology
  • arXiv (Cornell University)

Recent publications cover research in optical materials and dermatology, reflecting the interdisciplinary nature of their work. Notable papers include:

  • "Engineered second-order nonlinearity in silicon nitride," 2022, Optical Materials Express
  • "709 Malassezin: A preclinical assessment of a novel microbiome-based skin lightener," 2020, Journal of Investigative Dermatology
  • "Engineered second-order nonlinearity in silicon nitride," 2022, arXiv (Cornell University)

Frequent collaborators in Macdonald's work are:

  • Yi Zhang
  • Juniyali Nauriyal
  • Meiting Song
  • Marissa Granados Baez
  • Jaime Cárdenas

The scholar was recognized in 1981 as a Fellow of the Alfred P. Sloan Foundation.

Best Publications

  • Chemical mechanisms of catalysis by cytochromes P-450: a unified view

    F. Peter Guengerich;Timothy L. Macdonald

  • Immunosuppressive and Anti-Angiogenic Sphingosine 1-phosphate receptor-1 Agonists Induce Ubiquitinylation and Proteasomal Degradation of the Receptor

    Myat Lin Oo;Shobha Thangada;Ming-Tao Wu;Catherine H. Liu

  • S -Nitrosothiols signal the ventilatory response to hypoxia

    Andrew J. Lipton;Michael A. Johnson;Timothy Macdonald;Michael W. Lieberman

  • Sphingosine 1-phosphate analogs as receptor antagonists.

    Michael D. Davis;Jeremy J. Clemens;Timothy L. Macdonald;Kevin R. Lynch

  • Characterization of posttranslational modifications in neuron-specific class III beta-tubulin by mass spectrometry.

    Janice E. Alexander;Donald F. Hunt;Michael K. Lee;Jeffrey Shabanowitz

  • Aluminum ion in biological systems

    Unknown

  • Sphingosine Kinase 2 Is Required for Modulation of Lymphocyte Traffic by FTY720

    Yugesh Kharel;Sangderk Lee;Ashley H. Snyder;Stacey L. Sheasley-O'Neill

  • Selective A2A adenosine receptor activation reduces ischemia-reperfusion injury in rat kidney

    Mark D. Okusa;Joel Linden;Timothy Macdonald;Liping Huang

  • Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney

    Alaa S. Awad;Hong Ye;Liping Huang;Li Li

  • Cyclic AMP-dependent inhibition of human neutrophil oxidative activity by substituted 2-propynylcyclohexyl adenosine A2A receptor agonists

    Gail W Sullivan;Jayson M Rieger;W Michael Scheld;Timothy L Macdonald

  • A2A adenosine receptor-mediated inhibition of renal injury and neutrophil adhesion

    Mark D. Okusa;Joel Linden;Liping Huang;Jayson M. Rieger

  • Evidence for a 1-Electron Oxidation Mechanism in N-Dealkylation of N,N-Dialkylanilines by Cytochrome P450 2B1 KINETIC HYDROGEN ISOTOPE EFFECTS, LINEAR FREE ENERGY RELATIONSHIPS, COMPARISONS WITH HORSERADISH PEROXIDASE, AND STUDIES WITH OXYGEN SURROGATES

    F P Guengerich;C H Yun;T L Macdonald

  • Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists.

    Frank W. Foss;Ashley H. Snyder;Michael D. Davis;Michael Rouse

  • Allyloxy carbanions. New synthesis of aldehydes via a .beta.-acyl carbanion equivalent

    W. Clark Still;T. L. Macdonald

  • Physical properties and synthetic utility of .alpha.-alkoxyorganolithium species as studied through ligand selectivity in tin-lithium exchange

    J. Scott. Sawyer;Andrew. Kucerovy;Timothy L. Macdonald;Glenn J. McGarvey

  • In vitro metabolism of tolcapone to reactive intermediates: relevance to tolcapone liver toxicity.

    Kirsten S Smith;Philip L Smith;Tiffany N Heady;Joel M Trugman

  • Mechanism of cytochrome P-450 inhibition by cyclopropylamines

    Timothy L. Macdonald;Karimullah Zirvi;Leo T. Burka;Pamela Peyman

  • Mechanisms of cytochrome P‐450 catalysis

    Unknown

  • Reductive Assays forS-Nitrosothiols: Implications for Measurements in Biological Systems☆☆☆★

    Kezhong Fang;N.Virginia Ragsdale;Robert M. Carey;Timothy MacDonald

  • S-Nitrosothiols signal hypoxia-mimetic vascular pathology

    Lisa A. Palmer;Allan Doctor;Preeti Chhabra;Mary Lynn Sheram

  • Oxidation of substituted N,N-dimethylanilines by cytochrome P-450: estimation of the effective oxidation-reduction potential of cytochrome P-450

    Macdonald Tl;Gutheim Wg;Martin Rb;Guengerich Fp

  • Lysophosphatidic acid-induced mitogenesis is regulated by lipid phosphate phosphatases and is Edg-receptor independent.

    Shelley B. Hooks;Webster L. Santos;Dong-Soon Im;Christopher E. Heise

Frequent Co-Authors

Kevin R. Lynch
Kevin R. Lynch University of Virginia
Joel Linden
Joel Linden University of Virginia
George A. Beller
George A. Beller University of Virginia
Paul S. Hoffman
Paul S. Hoffman University of Virginia
Benjamin Gaston
Benjamin Gaston Indiana University
Yves Pommier
Yves Pommier National Institutes of Health
Richard L. Guerrant
Richard L. Guerrant University of Virginia
F. Peter Guengerich
F. Peter Guengerich Vanderbilt University
Edward Perez-Reyes
Edward Perez-Reyes University of Virginia
Eric R. Houpt
Eric R. Houpt University of Virginia

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Related Online Degrees & Career Pathways

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