2026 Kevin R. Lynch: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	95	1919	1731	1053	933	266	30496

Overview

Kevin R. Lynch is affiliated with the University of Virginia in the United States and has a primary research focus within biochemistry, genetics, and molecular biology. Their work spans several interconnected subfields including molecular biology, cell biology, materials chemistry, pathology and forensic medicine, and immunology.

The scientist's research topics are primarily concerned with sphingolipid metabolism and signaling, lipid membrane structure and behavior, cellular transport and secretion, protein kinase regulation and GTPase signaling, endoplasmic reticulum stress and disease, biomedical research and pathophysiology, and phagocytosis and immune regulation.

Recent publications by Kevin R. Lynch illustrate a concentration on sphingolipid-related cellular processes. These papers include:

Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney, 2022, Science Translational Medicine
Mechanism of sphingosine 1-phosphate clearance from blood, 2020, Biochemical Journal
Discovery of In Vivo Active Sphingosine-1-phosphate Transporter (Spns2) Inhibitors, 2022, Journal of Medicinal Chemistry
Discovery of a Small Side Cavity in Sphingosine Kinase 2 that Enhances Inhibitor Potency and Selectivity, 2020, Journal of Medicinal Chemistry
Lipophilic tail modifications of 2-(hydroxymethyl)pyrrolidine scaffold reveal dual sphingosine kinase 1 and 2 inhibitors, 2020, Bioorganic & Medicinal Chemistry

Kevin R. Lynch frequently publishes in the following scientific venues:

Journal of Medicinal Chemistry
Journal of the American Society of Nephrology
Biochemical Journal
bioRxiv (Cold Spring Harbor Laboratory)
Structural Dynamics

Collaboration is a notable aspect of their research activity. Frequent coauthors include:

Yugesh Kharel
Webster L. Santos
Tao Huang
Anne M. Brown
Shuqiu Zheng

The breadth of Kevin R. Lynch's work reflects an integration of biochemical and molecular investigations with pathophysiological contexts, contributing to the understanding of sphingolipid signaling pathways and their role in cellular processes and diseases.

Best Publications

The immune modulator FTY720 targets sphingosine 1-phosphate receptors.

Volker Brinkmann;Michael D. Davis;Christopher E. Heise;Rainer Albert

1822
Citations
Characterization of the human cysteinyl leukotriene CysLT1 receptor.

K. R. Lynch;G. P. O'neill;Qingyun Liu;D.-S. Im

1173
Citations
Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis

Susan Branford;Zbigniew Rudzki;Sonya Walsh;Ian Parkinson

1108
Citations
Regulation of learning and memory by meningeal immunity: a key role for IL-4

Noël C. Derecki;Amber N. Cardani;Chun Hui Yang;Kayla M. Quinnies

872
Citations
Characterization of the human cysteinyl leukotriene 2 receptor.

Christopher E. Heise;Brian F. O'Dowd;David J. Figueroa;Nicole Sawyer

844
Citations
Molecular cloning and expression of a cDNA encoding endothelial cell nitric oxide synthase.

W C Sessa;J K Harrison;C M Barber;D Zeng

634
Citations
International Union of Pharmacology. XXXIV. Lysophospholipid Receptor Nomenclature

Jerold Chun;Edward J. Goetzl;Timothy Hla;Yasuyuki Igarashi

611
Citations
Identification of receptors for neuromedin U and its role in feeding

Andrew D. Howard;Ruiping Wang;Sheng-Shung Pong;Theodore N. Mellin

573
Citations
Immunosuppressive and Anti-Angiogenic Sphingosine 1-phosphate receptor-1 Agonists Induce Ubiquitinylation and Proteasomal Degradation of the Receptor

Myat Lin Oo;Shobha Thangada;Ming-Tao Wu;Catherine H. Liu

565
Citations
A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat

Michael F. Jarvis;Edward C. Burgard;Steve McGaraughty;Prisca Honore

560
Citations
Discovery of a Novel Member of the Histamine Receptor Family

Tuan Nguyen;David A. Shapiro;Susan R. George;Vincent Setola

496
Citations
Characterization of a novel sphingosine 1-phosphate receptor, Edg-8.

Dong-Soon Im;Christopher E. Heise;Nicolas Ancellin;Brian F. O'Dowd

491
Citations
Identification and cloning of three novel human G protein-coupled receptor genes GPR52, ΨGPR53 and GPR55: GPR55 is extensively expressed in human brain

Marek Sawzdargo;Tuan Nguyen;Dennis K Lee;Kevin R Lynch

488
Citations
International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid Receptor Nomenclature

Jerold Chun;Timothy Hla;Kevin R. Lynch;Sarah Spiegel

437
Citations
Discovery of three novel G-protein-coupled receptor genes

Brian F. O'Dowd;Tuan Nguyen;Adriano Marchese;Regina Cheng

418
Citations
Astrocytes synthesize angiotensinogen in brain

Ruth L. Stornetta;Charlyn L. Hawelu-Johnson;Patrice G. Guyenet;Kevin R. Lynch

369
Citations
Distribution of α2C‐adrenergic receptor‐like immunoreactivity in the rat central nervous system

Diane L. Rosin;Edmund M. Talley;Amy Lee;Ruth L. Stornetta

346
Citations
Sphingosine-1-Phosphate Induces an Antiinflammatory Phenotype in Macrophages

Jeniter E. Hughes;Suseela Srinivasan;Kevin R. Lynch;Richard L. Proia

340
Citations
Sphingosine 1-phosphate analogs as receptor antagonists.

Michael D. Davis;Jeremy J. Clemens;Timothy L. Macdonald;Kevin R. Lynch

338
Citations
Lysophospholipid receptor nomenclature.

Kevin R Lynch

333
Citations