World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
20185
World Ranking
4365
National Ranking
22

Medicine

D-Index
80
Citations
20490
World Ranking
17248
National Ranking
48

Overview

Helen M. Roche is affiliated with University College Dublin in Ireland. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, with notable contributions to physiology, molecular biology, public health, genetics, and surgery.

The scientist has a broad publication record focusing on diet, metabolism, and health-related topics. Key themes in their work include:

  • Diet and metabolism studies
  • Nutrition and health in aging
  • Nutritional studies and diet
  • Nutrition, genetics, and disease
  • Muscle metabolism and nutrition
  • Gut microbiota and health
  • Diet, metabolism, and disease

Helen M. Roche's work has been published frequently in several academic venues, including:

  • Molecular Nutrition & Food Research (7 publications)
  • Proceedings of The Nutrition Society (6 publications)
  • American Journal of Clinical Nutrition (3 publications)
  • British Journal Of Nutrition (3 publications)
  • Advances in Nutrition (3 publications)

They have collaborated extensively with several researchers, notably:

  • Kathleen A. J. Mitchelson (12 coauthored papers)
  • Elena de Marco Castro (9 coauthored papers)
  • C. H. Murphy (7 coauthored papers)
  • Fiona C. McGillicuddy (7 coauthored papers)
  • Lorraine Brennan (6 coauthored papers)

Representative recent papers by Helen M. Roche include:

  • β-1,3/1,6-Glucans and Immunity: State of the Art and Future Directions, 2020, Molecular Nutrition & Food Research
  • Regulating metabolic inflammation by nutritional modulation, 2020, Journal of Allergy and Clinical Immunology
  • Research gaps and opportunities in precision nutrition: an NIH workshop report, 2022, American Journal of Clinical Nutrition
  • Obesity in Adults: A 2022 Adapted Clinical Practice Guideline for Ireland, 2022, Obesity Facts
  • Obesity, COVID-19 and innate immunometabolism, 2020, British Journal Of Nutrition

Best Publications

  • Low-grade inflammation, diet composition and health: current research evidence and its translation

    Anne-Marie Minihane;Sophie Vinoy;Wendy R. Russell;Athanasia Baka

  • Mechanisms of Obesity-Induced Inflammation and Insulin Resistance: Insights into the Emerging Role of Nutritional Strategies

    Maeve A. McArdle;Orla M. Finucane;Ruth M. Connaughton;Aoibheann M. McMorrow

  • METABOLOMICS IN HUMAN NUTRITION: OPPORTUNITIES AND CHALLENGES

    Michael J Gibney;Marianne Walsh;Lorraine Brennan;Helen M Roche

  • Low serum cholesteryl ester-docosahexaenoic acid levels in Alzheimer's disease: a case–control study

    A. M. Tully;H. M. Roche;R. Doyle;C. Fallon

  • Effect of long-chain n-3 polyunsaturated fatty acids on fasting and postprandial triacylglycerol metabolism.

    Helen M Roche;Michael J Gibney

  • Docosahexaenoic acid induces an anti-inflammatory profile in lipopolysaccharide-stimulated human THP-1 macrophages more effectively than eicosapentaenoic acid.

    Sinéad M Weldon;Anne C Mullen;Christine E Loscher;Lisa A Hurley

  • Effect of acute dietary standardization on the urinary, plasma, and salivary metabolomic profiles of healthy humans

    Marianne C Walsh;Lorraine Brennan;J Paul G Malthouse;Helen M Roche

  • Fats, inflammation and insulin resistance: insights to the role of macrophage and T-cell accumulation in adipose tissue.

    Karen A. Harford;Clare M. Reynolds;Fiona C. McGillicuddy;Helen M. Roche

  • The effect of dietary supplementation using isomeric blends of conjugated linoleic acid on lipid metabolism in healthy human subjects.

    Enda J. Noone;Helen M. Roche;Anne P. Nugent;Michael J. Gibney

  • Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus.

    Fiona Moloney;Toh-Peng Yeow;Anne Mullen;John J Nolan

  • Monounsaturated Fatty Acid–Enriched High-Fat Diets Impede Adipose NLRP3 Inflammasome–Mediated IL-1β Secretion and Insulin Resistance Despite Obesity

    Orla M. Finucane;Claire L. Lyons;Aoife M. Murphy;Clare M. Reynolds

  • Interferon γ Attenuates Insulin Signaling, Lipid Storage, and Differentiation in Human Adipocytes via Activation of the JAK/STAT Pathway

    Fiona C. McGillicuddy;Elise H. Chiquoine;Christine C. Hinkle;Roy J. Kim

  • Anti-inflammatory effects of EPA and DHA are dependent upon time and dose-response elements associated with LPS stimulation in THP-1-derived macrophages

    Anne Mullen;Christine E. Loscher;Helen M. Roche

  • Conjugated linoleic acid: a novel therapeutic nutrient?

    Helen M Roche;Enda Noone;Anne Nugent Michael J Gibney

  • Effects of dietary fat modification on insulin sensitivity and on other risk factors of the metabolic syndrome--LIPGENE: a European randomized dietary intervention study.

    A C Tierney;J McMonagle;D I Shaw;H I Gulseth;H I Gulseth

  • The metabolic syndrome: the crossroads of diet and genetics.

    Helen M. Roche;Catherine Phillips;Michael J. Gibney

  • Isomer-Dependent Metabolic Effects of Conjugated Linoleic Acid: Insights From Molecular Markers Sterol Regulatory Element-Binding Protein-1c and LXRα

    Helen M. Roche;Enda Noone;Ciaran Sewter;Siobhan Mc Bennett

  • Lack of Interleukin-1 Receptor I (IL-1RI) Protects Mice From High-Fat Diet–Induced Adipose Tissue Inflammation Coincident With Improved Glucose Homeostasis

    Fiona C. McGillicuddy;Karen A. Harford;Clare M. Reynolds;Elizabeth Oliver

  • Antidiabetic Effects of cis -9, trans -11–Conjugated Linoleic Acid May Be Mediated via Anti-Inflammatory Effects in White Adipose Tissue

    Fiona Moloney;Sinead Toomey;Enda Noone;Anne Nugent

  • Unsaturated fatty acids.

    Helen M. Roche

Frequent Co-Authors

Jose Lopez-Miranda
Jose Lopez-Miranda Instituto de Salud Carlos III
Michael J. Gibney
Michael J. Gibney University College Dublin
Ellen E. Blaak
Ellen E. Blaak Maastricht University
Christian A. Drevon
Christian A. Drevon University of Oslo
Ulf Risérus
Ulf Risérus Uppsala University
Francisco Perez-Jimenez
Francisco Perez-Jimenez Instituto de Salud Carlos III
Wim H. M. Saris
Wim H. M. Saris Maastricht University
Francisco J. Tinahones
Francisco J. Tinahones University of Malaga
Jose M. Ordovas
Jose M. Ordovas Tufts University
Denis Lairon
Denis Lairon Aix-Marseille University

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