Friedrich Koch-Nolte mainly investigates NAD+ kinase, Cell biology, Biochemistry, Extracellular and Molecular biology. His biological study spans a wide range of topics, including T cell, Cytotoxic T cell and Ligand. His research investigates the link between Cell biology and topics such as Immune system that cross with problems in Antigen and Tetraspanin.
His Biochemistry research focuses on subjects like Moiety, which are linked to Tankyrases. His work carried out in the field of Extracellular brings together such families of science as Receptor and Signal transduction. His work deals with themes such as Immunoprecipitation, Apoptosis, Mutant, c-Raf and EIF-2 kinase, which intersect with Molecular biology.
Friedrich Koch-Nolte spends much of his time researching Cell biology, Molecular biology, NAD+ kinase, Biochemistry and Antibody. His Cell biology study also includes
His research in NAD+ kinase tackles topics such as Extracellular which are related to areas like Signal transduction. Biochemistry and Moiety are frequently intertwined in his study. His studies deal with areas such as Recombinant DNA and In vivo as well as Antibody.
His scientific interests lie mostly in Cell biology, Antibody, NAD+ kinase, Receptor and Cytotoxic T cell. His study in the field of Extracellular is also linked to topics like Purinergic signalling. The NAD+ kinase study combines topics in areas such as Cell, Downregulation and upregulation, Programmed cell death and Intracellular.
Friedrich Koch-Nolte interconnects Molecular biology and T-cell receptor in the investigation of issues within Programmed cell death. His Receptor research includes themes of Tumor microenvironment and Cetuximab. The concepts of his Cytotoxic T cell study are interwoven with issues in Cancer research, Malaria and Immune system.
Friedrich Koch-Nolte mostly deals with Cell biology, Antibody, In vivo, Inflammation and NAD+ kinase. He works in the field of Cell biology, namely Extracellular. His In vivo research incorporates themes from Pathogenesis and Conditional gene knockout.
In general Inflammation, his work in Microglia is often linked to Grey matter linking many areas of study. Friedrich Koch-Nolte is studying ADP-ribosylation, which is a component of NAD+ kinase. His study in CD8 is interdisciplinary in nature, drawing from both Molecular biology and Receptor.
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Toward a unified nomenclature for mammalian ADP-ribosyltransferases
Michael O. Hottiger;Paul O. Hassa;Bernhard Lüscher;Herwig Schüler.
Trends in Biochemical Sciences (2010)
Single domain antibodies: promising experimental and therapeutic tools in infection and immunity.
Janusz Wesolowski;Vanina Alzogaray;Jan Reyelt;Mandy Unger.
Medical Microbiology and Immunology (2009)
NAD-Induced T Cell Death: ADP-Ribosylation of Cell Surface Proteins by ART2 Activates the Cytolytic P2X7 Purinoceptor
Michel Seman;Sahil Adriouch;Felix Scheuplein;Christian Krebs.
Liver-Resident Memory CD8 + T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.
Daniel Fernandez-Ruiz;Wei Yi Ng;Wei Yi Ng;Lauren E Holz;Joel Z Ma.
In silico characterization of the family of PARP-like poly(ADP-ribosyl)transferases (pARTs).
Helge Otto;Pedro A Reche;Fernando Bazan;Katharina Dittmar.
BMC Genomics (2005)
Cutting edge: a natural P451L mutation in the cytoplasmic domain impairs the function of the mouse P2X7 receptor.
Sahil Adriouch;Claudia Dox;Vivienne Welge;Michel Seman.
Journal of Immunology (2002)
The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse.
Gustavo Glowacki;Rickmer Braren;Kathrin Firner;Marion Nissen.
Protein Science (2009)
Nanobodies and Nanobody-Based Human Heavy Chain Antibodies As Antitumor Therapeutics.
Peter Bannas;Julia Hambach;Friedrich Koch-Nolte.
Frontiers in Immunology (2017)
Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding
Christoph Garbers;Nathalie Jänner;Athena Chalaris;Marcia L. Moss.
Journal of Biological Chemistry (2011)
Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2–P2X7 pathway
Sandra Hubert;Björn Rissiek;Katjana Klages;Jochen Huehn.
Journal of Experimental Medicine (2010)
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