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Friedrich Koch-Nolte

Friedrich Koch-Nolte

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
16844
World Ranking
6701
National Ranking
481

Overview

Friedrich Koch-Nolte is affiliated with Universität Hamburg in Germany and has contributed extensively to the fields of medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. Their research spans several subfields, including physiology, immunology, radiology, nuclear medicine and imaging, molecular biology, and oncology.

The scientist's published work covers a range of topics, particularly focused on adenosine and purinergic signaling, immune cell function and interaction, monoclonal and polyclonal antibodies research, calcium signaling and nucleotide metabolism, adolescent and pediatric healthcare, T-cell and B-cell immunology, and the complement system in diseases.

Freidrich Koch-Nolte has published articles in frequent venues such as Frontiers in Immunology, bioRxiv (Cold Spring Harbor Laboratory), Nature, Nature Communications, and the European Journal of Immunology.

Recent notable papers include:

  • Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH (2021, Nature)
  • Pathogen-induced tissue-resident memory T H 17 (T RM 17) cells amplify autoimmune kidney disease (2020, Science Immunology)
  • The classical pathway triggers pathogenic complement activation in membranous nephropathy (2023, Nature Communications)
  • Natural killer cell-mediated ADCC in SARS-CoV-2-infected individuals and vaccine recipients (2022, European Journal of Immunology)
  • Targeting CD38-Expressing Multiple Myeloma and Burkitt Lymphoma Cells In Vitro with Nanobody-Based Chimeric Antigen Receptors (Nb-CARs) (2020, Cells)

Friedrich Koch-Nolte has frequently collaborated with other researchers, including:

  • Björn Rissiek
  • Stephan Menzel
  • Friedrich Haag
  • Tim Magnus
  • Tobias Stähler

Best Publications

  • Toward a unified nomenclature for mammalian ADP-ribosyltransferases

    Michael O. Hottiger;Paul O. Hassa;Bernhard Lüscher;Herwig Schüler

  • Single domain antibodies: promising experimental and therapeutic tools in infection and immunity.

    Janusz Wesolowski;Vanina Alzogaray;Jan Reyelt;Mandy Unger

  • Nanobodies and Nanobody-Based Human Heavy Chain Antibodies As Antitumor Therapeutics.

    Peter Bannas;Julia Hambach;Friedrich Koch-Nolte

  • Liver-Resident Memory CD8 + T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.

    Daniel Fernandez-Ruiz;Wei Yi Ng;Wei Yi Ng;Lauren E Holz;Joel Z Ma

  • Auto-aggressive CXCR6 + CD8 T cells cause liver immune pathology in NASH

    Michael Dudek;Dominik Pfister;Sainitin Donakonda;Pamela Filpe

  • NAD-Induced T Cell Death: ADP-Ribosylation of Cell Surface Proteins by ART2 Activates the Cytolytic P2X7 Purinoceptor

    Michel Seman;Sahil Adriouch;Felix Scheuplein;Christian Krebs

  • In silico characterization of the family of PARP-like poly(ADP-ribosyl)transferases (pARTs).

    Helge Otto;Pedro A Reche;Fernando Bazan;Katharina Dittmar

  • Purine Release, Metabolism, and Signaling in the Inflammatory Response.

    Joel Linden;Joel Linden;Friedrich Koch-Nolte;Gerhard Dahl

  • Cutting edge: a natural P451L mutation in the cytoplasmic domain impairs the function of the mouse P2X7 receptor.

    Sahil Adriouch;Claudia Dox;Vivienne Welge;Michel Seman

  • Autoantibodies against thrombospondin type 1 domain-containing 7A induce membranous nephropathy.

    Nicola M. Tomas;Elion Hoxha;Anna T. Reinicke;Lars Fester

  • Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2–P2X7 pathway

    Sandra Hubert;Björn Rissiek;Katjana Klages;Jochen Huehn

  • The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse.

    Gustavo Glowacki;Rickmer Braren;Kathrin Firner;Marion Nissen

  • Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding

    Christoph Garbers;Nathalie Jänner;Athena Chalaris;Marcia L. Moss

  • Extracellular NAD and ATP: Partners in immune cell modulation.

    Friedrich Haag;Sahil Adriouch;Anette Braß;Caroline Jung

  • A PKR-like eukaryotic initiation factor 2α kinase from zebrafish contains Z-DNA binding domains instead of dsRNA binding domains

    Stefan Rothenburg;Nikolaus Deigendesch;Katharina Dittmar;Friedrich Koch-Nolte

  • The binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia

    Carrie A. Cowardin;Erica L. Buonomo;Mahmoud M. Saleh;Madeline G. Wilson

  • P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis

    Juan José Martínez-García;Helios Martínez-Banaclocha;Diego Angosto-Bazarra;Carlos de Torre-Minguela

  • A polymorphic dinucleotide repeat in the rat nucleolin gene forms Z-DNA and inhibits promoter activity.

    Stefan Rothenburg;Friedrich Koch-Nolte;Alexander Rich;Friedrich Haag

  • Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-Butyl) phthalate.

    Chris McKinnell;Richard M. Sharpe;Kim Mahood;Nina Hallmark

  • ADP-ribosylation of arginine

    Sabrina Laing;Mandy Unger;Friedrich Koch-Nolte;Friedrich Haag

Frequent Co-Authors

Friedrich Haag
Friedrich Haag Universität Hamburg
Hans-Willi Mittrücker
Hans-Willi Mittrücker Universität Hamburg
Edward H. Leiter
Edward H. Leiter The Jackson Laboratory
Olivier Boyer
Olivier Boyer University of Rouen
Mathias Ziegler
Mathias Ziegler University of Bergen
Irina Caminschi
Irina Caminschi Monash University
George R. Dubyak
George R. Dubyak Case Western Reserve University
Geoffrey I. McFadden
Geoffrey I. McFadden University of Melbourne
Malik Alawi
Malik Alawi University Medical Center Hamburg-Eppendorf
Brendan S. Crabb
Brendan S. Crabb Monash University

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