D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 65 Citations 12,476 244 World Ranking 6018 National Ranking 429

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Friedrich Koch-Nolte mainly investigates NAD+ kinase, Cell biology, Biochemistry, Extracellular and Molecular biology. His biological study spans a wide range of topics, including T cell, Cytotoxic T cell and Ligand. His research investigates the link between Cell biology and topics such as Immune system that cross with problems in Antigen and Tetraspanin.

His Biochemistry research focuses on subjects like Moiety, which are linked to Tankyrases. His work carried out in the field of Extracellular brings together such families of science as Receptor and Signal transduction. His work deals with themes such as Immunoprecipitation, Apoptosis, Mutant, c-Raf and EIF-2 kinase, which intersect with Molecular biology.

His most cited work include:

  • Toward a unified nomenclature for mammalian ADP-ribosyltransferases (572 citations)
  • Single domain antibodies: promising experimental and therapeutic tools in infection and immunity. (462 citations)
  • NAD-Induced T Cell Death: ADP-Ribosylation of Cell Surface Proteins by ART2 Activates the Cytolytic P2X7 Purinoceptor (264 citations)

What are the main themes of his work throughout his whole career to date?

Friedrich Koch-Nolte spends much of his time researching Cell biology, Molecular biology, NAD+ kinase, Biochemistry and Antibody. His Cell biology study also includes

  • Cytotoxic T cell most often made with reference to T cell,
  • Immune system and related Inflammation. His studies in Molecular biology integrate themes in fields like Genetics, In vitro, Apoptosis, Antigen and Gene.

His research in NAD+ kinase tackles topics such as Extracellular which are related to areas like Signal transduction. Biochemistry and Moiety are frequently intertwined in his study. His studies deal with areas such as Recombinant DNA and In vivo as well as Antibody.

He most often published in these fields:

  • Cell biology (28.82%)
  • Molecular biology (27.95%)
  • NAD+ kinase (24.02%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cell biology (28.82%)
  • Antibody (12.66%)
  • NAD+ kinase (24.02%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cell biology, Antibody, NAD+ kinase, Receptor and Cytotoxic T cell. His study in the field of Extracellular is also linked to topics like Purinergic signalling. The NAD+ kinase study combines topics in areas such as Cell, Downregulation and upregulation, Programmed cell death and Intracellular.

Friedrich Koch-Nolte interconnects Molecular biology and T-cell receptor in the investigation of issues within Programmed cell death. His Receptor research includes themes of Tumor microenvironment and Cetuximab. The concepts of his Cytotoxic T cell study are interwoven with issues in Cancer research, Malaria and Immune system.

Between 2017 and 2021, his most popular works were:

  • P2X4 receptor controls microglia activation and favors remyelination in autoimmune encephalitis (61 citations)
  • Purine Release, Metabolism, and Signaling in the Inflammatory Response. (53 citations)
  • Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody. (51 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Friedrich Koch-Nolte mostly deals with Cell biology, Antibody, In vivo, Inflammation and NAD+ kinase. He works in the field of Cell biology, namely Extracellular. His In vivo research incorporates themes from Pathogenesis and Conditional gene knockout.

In general Inflammation, his work in Microglia is often linked to Grey matter linking many areas of study. Friedrich Koch-Nolte is studying ADP-ribosylation, which is a component of NAD+ kinase. His study in CD8 is interdisciplinary in nature, drawing from both Molecular biology and Receptor.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Toward a unified nomenclature for mammalian ADP-ribosyltransferases

Michael O. Hottiger;Paul O. Hassa;Bernhard Lüscher;Herwig Schüler.
Trends in Biochemical Sciences (2010)

746 Citations

Single domain antibodies: promising experimental and therapeutic tools in infection and immunity.

Janusz Wesolowski;Vanina Alzogaray;Jan Reyelt;Mandy Unger.
Medical Microbiology and Immunology (2009)

632 Citations

NAD-Induced T Cell Death: ADP-Ribosylation of Cell Surface Proteins by ART2 Activates the Cytolytic P2X7 Purinoceptor

Michel Seman;Sahil Adriouch;Felix Scheuplein;Christian Krebs.
Immunity (2003)

347 Citations

Liver-Resident Memory CD8 + T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.

Daniel Fernandez-Ruiz;Wei Yi Ng;Wei Yi Ng;Lauren E Holz;Joel Z Ma.
Immunity (2016)

317 Citations

In silico characterization of the family of PARP-like poly(ADP-ribosyl)transferases (pARTs).

Helge Otto;Pedro A Reche;Fernando Bazan;Katharina Dittmar.
BMC Genomics (2005)

276 Citations

Cutting edge: a natural P451L mutation in the cytoplasmic domain impairs the function of the mouse P2X7 receptor.

Sahil Adriouch;Claudia Dox;Vivienne Welge;Michel Seman.
Journal of Immunology (2002)

241 Citations

The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse.

Gustavo Glowacki;Rickmer Braren;Kathrin Firner;Marion Nissen.
Protein Science (2009)

209 Citations

Nanobodies and Nanobody-Based Human Heavy Chain Antibodies As Antitumor Therapeutics.

Peter Bannas;Julia Hambach;Friedrich Koch-Nolte.
Frontiers in Immunology (2017)

195 Citations

Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding

Christoph Garbers;Nathalie Jänner;Athena Chalaris;Marcia L. Moss.
Journal of Biological Chemistry (2011)

181 Citations

Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2–P2X7 pathway

Sandra Hubert;Björn Rissiek;Katjana Klages;Jochen Huehn.
Journal of Experimental Medicine (2010)

181 Citations

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