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Bernhard Lüscher

Bernhard Lüscher

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Biology and Biochemistry
Germany
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
99
Citations
43304
World Ranking
1568
National Ranking
102

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Germany Leader Award
  • 2025 - Research.com Biology and Biochemistry in Germany Leader Award

Overview

Bernhard Lüscher is affiliated with RWTH Aachen University in Germany, contributing extensively to the fields of neuroscience, biochemistry, genetics, molecular biology, and medicine. Their research focuses on molecular biology, biological psychiatry, cellular and molecular neuroscience, and behavioral neuroscience, among other subfields.

Their recent work covers various topics including tryptophan and brain disorders, neuroscience and neuropharmacology research, stress responses and cortisol, nicotinic acetylcholine receptors, pregnancy and preeclampsia studies, gestational diabetes research and management, and neuroendocrine regulation and behavior.

Bernhard Lüscher has published notable papers such as:

  • GABAA receptors as targets for treating affective and cognitive symptoms of depression (2023, Trends in Pharmacological Sciences)
  • Antidepressant mechanisms of ketamine: Focus on GABAergic inhibition (2020, Advances in Pharmacology)

They have collaborated frequently with coauthors including Uwe Rudolph, Mengyang Feng, Delia Belelli, Tim G. Hales, and Jeremy J. Lambert. Publication venues commonly featuring their work include the IUPHAR/BPS Guide to Pharmacology CITE, Cells, Molecular Psychiatry, bioRxiv (Cold Spring Harbor Laboratory), and Trends in Pharmacological Sciences.

The scope of Lüscher's studies integrates biological psychiatry and molecular neuroscience, often exploring complex mechanisms underlying affective and cognitive disorders. Their research emphasizes neuropharmacological targets such as GABAA receptors and inhibitory pathways relevant to depression and ketamine's antidepressant effects.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Proteins of the Myc Network: Essential Regulators of Cell Growth and Differentiation

    Marie Henriksson;Bernhard Lüscher

  • Toward a unified nomenclature for mammalian ADP-ribosyltransferases

    Michael O. Hottiger;Paul O. Hassa;Bernhard Lüscher;Herwig Schüler

  • The GABAergic deficit hypothesis of major depressive disorder

    Bernhard Luscher;Qiuying Shen;Nadia Sahir

  • Decreased GABA A -receptor clustering results in enhanced anxiety and a bias for threat cues

    Florence Crestani;Matthias Lorez;Kristin Baer;Christian Essrich

  • Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements.

    T Williams;A Admon;B Lüscher;R Tjian

  • New light on Myc and Myb. Part II. Myb.

    B Lüscher;R N Eisenman

  • Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision

    Juan Song;Chun Zhong;Michael A. Bonaguidi;Gerald J. Sun

  • Myc and Max associate in vivo

    E M Blackwood;B Lüscher;R N Eisenman

  • Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors

    Uwe Gunther;Jack Benson;Dietmar Benke;Jean-Marc Fritschy

  • Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive.

    Ernesto Guccione;Christian Bassi;Fabio Casadio;Francesca Martinato

  • GABAA Receptor Trafficking-Mediated Plasticity of Inhibitory Synapses

    Bernhard Luscher;Thomas Fuchs;Casey L. Kilpatrick

  • Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activity

    H Lue;M Thiele;J Franz;E Dahl

  • Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter

    Caroline Bouchard;Oliver Dittrich;Astrid Kiermaier;Karen Dohmann

  • Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation

    Bernhard Lüscher;Erik Christenson;David W. Litchfield;Edwin G. Krebs

  • Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation.

    Henning Kleine;Elzbieta Poreba;Krzysztof Lesniewicz;Paul O. Hassa

  • SIRT2 regulates NF-κB-dependent gene expression through deacetylation of p65 Lys310

    Karin M. Rothgiesser;Süheda Erener;Susanne Waibel;Bernhard Lüscher

  • Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity.

    Y. F. Hu;Bernhard Luscher;A. Admon;N. Mermod

  • Regulation of GABAA receptor trafficking, channel activity, and functional plasticity of inhibitory synapses.

    Bernhard Lüscher;Cheryl A Keller

  • Myc oncoproteins are phosphorylated by casein kinase II.

    B Lüscher;E A Kuenzel;E G Krebs;R N Eisenman

Frequent Co-Authors

Robert N. Eisenman
Robert N. Eisenman Fred Hutchinson Cancer Research Center
David W. Litchfield
David W. Litchfield University of Western Ontario
Elisabeth Kremmer
Elisabeth Kremmer Max Planck Society
Jean-Marc Fritschy
Jean-Marc Fritschy University of Zurich
Gerhard Müller-Newen
Gerhard Müller-Newen RWTH Aachen University
Michael O. Hottiger
Michael O. Hottiger University of Zurich
Hanns Möhler
Hanns Möhler University of Zurich
Jan Senderek
Jan Senderek Ludwig-Maximilians-Universität München
Paolo Carloni
Paolo Carloni Forschungszentrum Jülich
Elmar G. Weinhold
Elmar G. Weinhold RWTH Aachen University

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