World's Best Scientists 2026 revealed!

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Molecular Biology

D-Index
47
Citations
11337
World Ranking
2724
National Ranking
1319

Overview

Anthony K.L. Leung is affiliated with Johns Hopkins University in the United States. Their research spans multiple subfields within biochemistry, genetics, molecular biology, and medicine, focusing particularly on molecular biology, oncology, immunology, physiology, and cardiology and cardiovascular medicine.

The scientist's work extensively addresses topics such as PARP inhibition in cancer therapy, RNA research and splicing, calcium signaling and nucleotide metabolism, toxin mechanisms and immunotoxins, RNA and protein synthesis mechanisms, RNA modifications and cancer, and viral infections and immunology research.

Anthony K.L. Leung has published numerous papers, including the following notable recent works:

  • Poly(ADP-ribose): A Dynamic Trigger for Biomolecular Condensate Formation, 2020, Trends in Cell Biology
  • ADP-ribosyltransferases, an update on function and nomenclature, 2021, FEBS Journal
  • Structure-Mediated RNA Decay by UPF1 and G3BP1, 2020, Molecular Cell
  • The DarTG toxin-antitoxin system provides phage defence by ADP-ribosylating viral DNA, 2022, Nature Microbiology
  • Stress granule formation, disassembly, and composition are regulated by alphavirus ADP-ribosylhydrolase activity, 2021, Proceedings of the National Academy of Sciences

Their frequent collaborators include Morgan Dasovich, Mohsen Badiee, Isabel Uribe, Veronica F. Busa, and Sua Myong.

Anthony K.L. Leung's research has been published across several venues, with a significant number of publications in bioRxiv (Cold Spring Harbor Laboratory). Other common publication venues include the Proceedings of the National Academy of Sciences, Nature Communications, Molecular Cell, and SSRN Electronic Journal.

Best Publications

  • Nucleolar proteome dynamics

    Jens S. Andersen;Yun W. Lam;Anthony K.L. Leung;Shao En Ong

  • Directed proteomic analysis of the human nucleolus.

    Jens S. Andersen;Carol E. Lyon;Archa H. Fox;Anthony K.L. Leung

  • MicroRNA functions in stress responses.

    Anthony K.L. Leung;Phillip A. Sharp

  • Paraspeckles: a novel nuclear domain.

    Archa H. Fox;Yun Wah Lam;Anthony K.L. Leung;Carol E. Lyon

  • Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules

    Anthony K. L. Leung;J. Mauro Calabrese;Phillip A. Sharp

  • Poly(ADP-Ribose) Regulates Stress Responses and MicroRNA Activity in the Cytoplasm

    Anthony K.L. Leung;Sejal Vyas;Jennifer E. Rood;Arjun Bhutkar

  • Genome-wide identification of Ago2 binding sites from mouse embryonic stem cells with and without mature microRNAs

    Anthony K L Leung;Amanda G Young;Amanda G Young;Arjun Bhutkar;Grace X Zheng;Grace X Zheng

  • microRNAs: A Safeguard against Turmoil?

    Anthony K.L. Leung;Phillip A. Sharp

  • Condensed mitotic chromatin is accessible to transcription factors and chromatin structural proteins

    Danyang Chen;Miroslav Dundr;Chen Wang;Anthony Leung

  • ADP-ribosyltransferases, an update on function and nomenclature

    Bernhard Lüscher;Ivan Ahel;Matthias Altmeyer;Alan Ashworth

  • The Promise of Proteomics for the Study of ADP-Ribosylation.

    Casey M. Daniels;Shao En Ong;Anthony K.L. Leung

  • Quantitative kinetic analysis of nucleolar breakdown and reassembly during mitosis in live human cells

    Anthony Kar Lun Leung;Daniel W. Gerlich;Gail Miller;Gail Miller;Carol Lyon

  • The Whereabouts of microRNA Actions: Cytoplasm and Beyond

    Anthony K.L. Leung

  • Structure-Mediated RNA Decay by UPF1 and G3BP1

    Joseph W. Fischer;Joseph W. Fischer;Veronica F. Busa;Veronica F. Busa;Yue Shao;Anthony K.L. Leung

  • Poly(ADP-ribose): An organizer of cellular architecture

    Anthony K.L. Leung

  • Dynamic regulation of RNA editing in human brain development and disease

    Taeyoung Hwang;Chul Kee Park;Anthony K.L. Leung;Yuan Gao

  • Bioinformatic analysis of the nucleolus.

    Anthony K L Leung;Jens S Andersen;Matthias Mann;Angus I Lamond

  • CircRNAs: a regulator of cellular stress

    Joseph W. Fischer;Anthony K. L. Leung

  • Mechanism of N-acetylgalactosamine binding to a C-type animal lectin carbohydrate-recognition domain

    Anand R. Kolatkar;Anthony K. Leung;Rainer Isecke;Reinhard Brossmer

  • NOPdb: Nucleolar Proteome Database

    Anthony Kar Lun Leung;Laura Trinkle-Mulcahy;Yun Wah Lam;Jens S. Andersen

Frequent Co-Authors

Angus I. Lamond
Angus I. Lamond University of Dundee
Diane E. Griffin
Diane E. Griffin Johns Hopkins University
Jens S. Andersen
Jens S. Andersen University of Southern Denmark
Matthias Mann
Matthias Mann Max Planck Institute of Biochemistry
Richard A. Flavell
Richard A. Flavell Yale University
Charles Steenbergen
Charles Steenbergen Johns Hopkins University
Ambrosius P. Snijders
Ambrosius P. Snijders The Francis Crick Institute
Ivan Ahel
Ivan Ahel University of Oxford
Marc M. Greenberg
Marc M. Greenberg Johns Hopkins University

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