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Molecular Biology

D-Index
78
Citations
31401
World Ranking
1061
National Ranking
554

Overview

Nancy Kedersha is affiliated with Brigham and Women's Hospital in the United States and has contributed extensively to the fields of biochemistry, genetics, and molecular biology. Their research primarily focuses on molecular biology, with considerable work addressing cell biology, oncology, health, toxicology, mutagenesis, and physiology.

Their scientific contributions explore a range of topics, including:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • Nuclear Structure and Function
  • Ubiquitin and proteasome pathways
  • Heat shock proteins research
  • RNA regulation and disease
  • RNA and protein synthesis mechanisms

Kedersha's recent publications include:

  • "Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization," 2020, published in Cell
  • "Mammalian stress granules and P bodies at a glance," 2020, published in Journal of Cell Science
  • "Molecular mechanisms of stress granule assembly and disassembly," 2020, published in Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  • "Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis," 2020, published in Molecular Cell
  • "TSC2 Interacts with HDLBP/Vigilin and Regulates Stress Granule Formation," 2021, published in Molecular Cancer Research

Frequent coauthors collaborating with Kedersha include:

  • Paul Anderson
  • Pavel Ivanov
  • Claire L. Riggs
  • Aviad Siany
  • Naama Knafo

Kedersha's work is featured often in publications such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell
  • Journal of Cell Science
  • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  • Molecular Cell

Best Publications

  • Stress granules and processing bodies are dynamically linked sites of mRNP remodeling

    Nancy Kedersha;Georg Stoecklin;Maranatha Ayodele;Patrick Yacono

  • RNA-Binding Proteins Tia-1 and Tiar Link the Phosphorylation of Eif-2α to the Assembly of Mammalian Stress Granules

    Nancy L. Kedersha;Mita Gupta;Wei Li;Ira Miller

  • Stress granules: the Tao of RNA triage

    Paul Anderson;Nancy Kedersha

  • Stress Granule Assembly Is Mediated by Prion-like Aggregation of TIA-1

    Natalie Gilks;Nancy Kedersha;Maranatha Ayodele;Lily Shen

  • RNA granules: post-transcriptional and epigenetic modulators of gene expression

    Paul Anderson;Nancy Kedersha

  • Stress granules: sites of mRNA triage that regulate mRNA stability and translatability.

    N.L. Kedersha;P. Anderson

  • Dynamic shuttling of TIA-1 accompanies the recruitment of mRNA to mammalian stress granules.

    Nancy Kedersha;Michael R. Cho;Wei Li;Patrick W. Yacono

  • Mammalian stress granules and processing bodies.

    Nancy Kedersha;Paul Anderson

  • Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules.

    Nancy Kedersha;Samantha Chen;Natalie Gilks;Wei Li

  • Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization

    David W. Sanders;Nancy Kedersha;Daniel S.W. Lee;Amy R. Strom

  • Stress granules and cell signaling: more than just a passing phase?

    Nancy Kedersha;Pavel Ivanov;Paul Anderson

  • MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay

    Georg Stoecklin;Tiffany Stubbs;Nancy Kedersha;Stephen Wax

  • TIA-1 is a translational silencer that selectively regulates the expression of TNF-α

    Monica Piecyk;Stephen Wax;Andreas R.P. Beck;Nancy Kedersha

  • Heme-regulated Inhibitor Kinase-mediated Phosphorylation of Eukaryotic Translation Initiation Factor 2 Inhibits Translation, Induces Stress Granule Formation, and Mediates Survival upon Arsenite Exposure

    Edward McEwen;Nancy Kedersha;Benbo Song;Donalyn Scheuner

  • G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits

    Nancy Kedersha;Marc D. Panas;Christopher A. Achorn;Shawn Lyons

  • A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2

    Victor S. Goldmacher;Laura M. Bartle;Anna Skaletskaya;Cheryl A. Dionne

  • Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics

    Steven Boeynaems;Elke Bogaert;Denes Kovacs;Albert Konijnenberg

  • The 193-Kd Vault Protein, Vparp, Is a Novel Poly(Adp-Ribose) Polymerase

    Valerie A. Kickhoefer;Amara C. Siva;Nancy L. Kedersha;Elisabeth M. Inman

  • Angiogenin-induced tRNA-derived Stress-induced RNAs Promote Stress-induced Stress Granule Assembly

    Mohamed M. Emara;Pavel Ivanov;Tyler Hickman;Nemisha Dawra

  • A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly.

    Takbum Ohn;Nancy Kedersha;Tyler Hickman;Sarah Tisdale

Frequent Co-Authors

Pavel Ivanov
Pavel Ivanov Brigham and Women's Hospital
Leonard H. Rome
Leonard H. Rome University of California, Los Angeles
Georg Stoecklin
Georg Stoecklin Heidelberg University
Randal J. Kaufman
Randal J. Kaufman Sanford Burnham Prebys Medical Discovery Institute
Michel Streuli
Michel Streuli Harvard University
Victor S. Goldmacher
Victor S. Goldmacher ImmunoGen (United States)
Diane C. Chugani
Diane C. Chugani Wayne State University
David E. Golan
David E. Golan Harvard Medical School
Myriam Gorospe
Myriam Gorospe National Institutes of Health

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