Kari I. Kivirikko

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Finland Leader Award
• 2025 - Research.com Biology and Biochemistry in Finland Leader Award
• 2023 - Research.com Biology and Biochemistry in Finland Leader Award
• 2022 - Research.com Biology and Biochemistry in Finland Leader Award
• 1989 - Member of Academia Europaea

Overview

Best Publications

• COLLAGENS: Molecular Biology, Diseases, and Potentials for Therapy

  Darwin J. Prockop;Kari I. Kivirikko

  1962
  Citations

• Collagens, modifying enzymes and their mutations in humans, flies and worms

  Johanna Myllyharju;Kari I. Kivirikko

  1539
  Citations

• Modifications of a specific assay for hydroxyproline in urine

  Kari I. Kivirikko;Ossi Laitinen;Darwin J. Prockop

  1326
  Citations

• Collagens and collagen-related diseases

  Johanna Myllyharju;Kari I Kivirikko

  993
  Citations

• Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor.

  Maija Hirsilä;Peppi Koivunen;Volkmar Günzler;Kari I. Kivirikko

  972
  Citations

• The biosynthesis of collagen and its disorders (second of two parts).

  D J Prockop;K I Kivirikko;L Tuderman;N A Guzman

  691
  Citations

• Inactivation of the Lysyl Oxidase Gene Lox Leads to Aortic Aneurysms, Cardiovascular Dysfunction, and Perinatal Death in Mice

  Joni M. Mäki;Juha Räsänen;Hilkka Tikkanen;Raija Sormunen

  675
  Citations

• Inhibition of Hypoxia-inducible Factor (HIF) Hydroxylases by Citric Acid Cycle Intermediates POSSIBLE LINKS BETWEEN CELL METABOLISM AND STABILIZATION OF HIF

  Peppi Koivunen;Maija Hirsilä;Anne M. Remes;Ilmo E. Hassinen

  624
  Citations

• Molecular cloning of the beta-subunit of human prolyl 4-hydroxylase. This subunit and protein disulphide isomerase are products of the same gene.

  T. Pihlajaniemi;T. Helaakoski;K. Tasanen;R. Myllylä

  592
  Citations

• Posttranslational enzymes in the biosynthesis of collagen: intracellular enzymes.

  Kari I. Kivirikko;Raili Myllylä

  536
  Citations

• Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.

  Peppi Koivunen;Maija Hirsilä;Volkmar Günzler;Kari I. Kivirikko

  525
  Citations

• Collagen Hydroxylases and the Protein Disulfide Isomerase Subunit of Prolyl 4‐Hydroxylases

  Kari I. Kivirikko;Taina Pihlajaniemi

  429
  Citations

• Protein hydroxylation: prolyl 4-hydroxylase, an enzyme with four cosubstrates and a multifunctional subunit.

  Kari I. Kivirikko;Raili Myllylä;Taina Pihlajaniemi

  427
  Citations

• Prolyl 4-hydroxylases and their protein disulfide isomerase subunit

  Kari I. Kivirikko;Johanna Myllyharju

  409
  Citations

• Mechanism of the prolyl hydroxylase reaction. 2. Kinetic analysis of the reaction sequence.

  Raili Myllylä;Leena Tuderman;Kari I. Kivirikko

  365
  Citations

• Relationship of Hydroxyproline Excretion in Urine to Collagen Metabolism: Biochemistry and Clinical Applications

  Darwin J. Prockop;Kari I. Kivirikko

  345
  Citations

• Mechanism of the prolyl hydroxylase reaction. 1. Role of co-substrates.

  Leena Tuderman;Raili Myllyla;Kari I. Kivirikko

  327
  Citations

• Ascorbate is consumed stoichiometrically in the uncoupled reactions catalyzed by prolyl 4-hydroxylase and lysyl hydroxylase.

  R Myllylä;K Majamaa;V Günzler;H M Hanauske-Abel

  326
  Citations

• A single polypeptide acts both as the beta subunit of prolyl 4-hydroxylase and as a protein disulfide-isomerase.

  J Koivu;R Myllylä;T Helaakoski;T Pihlajaniemi

  325
  Citations

• Collagens and their abnormalities in a wide spectrum of diseases.

  Kari I. Kivirikko

  314
  Citations