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Molecular Biology

D-Index
44
Citations
13674
World Ranking
2894
National Ranking
1379

Overview

Luiz O. F. Penalva is affiliated with The University of Texas Health Science Center at San Antonio in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics, and Molecular Biology, with 70 publications in these areas. Within these main fields, their work extends into several subfields of study including Molecular Biology, Cancer Research, Oncology, Immunology, and Genetics.

Their research covers numerous topics closely related to RNA and cancer biology. The main topics include:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • RNA and protein synthesis mechanisms
  • Cancer, Hypoxia, and Metabolism
  • MicroRNA in disease regulation
  • Cancer Cells and Metastasis

Penalva has published several papers that address various aspects of glioblastoma and RNA-binding proteins. Notable recent papers include:

  • "Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis," 2020, published in Cell Stem Cell
  • "The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation," 2020, published in Genome Biology
  • "Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches," 2021, published in Acta Neuropathologica Communications
  • "Proneural and mesenchymal glioma stem cells display major differences in splicing and lncRNA profiles," 2020, published in npj Genomic Medicine
  • "Structural Characterization of the RNA-Binding Protein SERBP1 Reveals Intrinsic Disorder and Atypical RNA Binding Modes," 2021, published in Frontiers in Molecular Biosciences

Frequent coauthors collaborating with Penalva include Gabriela D. A. Guardia, Pedro A. F. Galante, Qiao Mei, Xiufen Lei, and Adam Kosti.

Their work is disseminated in a range of scientific venues with multiple publications appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancers
  • Neuro-Oncology
  • Scientific Reports
  • Cancer Research

Best Publications

  • An integrated encyclopedia of DNA elements in the human genome

    Ian Dunham;Anshul Kundaje;Shelley F. Aldred;Patrick J. Collins

  • A compendium of RNA-binding motifs for decoding gene regulation

    Debashish Ray;Hilal Kazan;Kate B. Cook;Matthew T. Weirauch;Matthew T. Weirauch

  • A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

    Richard M. Myers;John Stamatoyannopoulos;Michael Snyder;Ian Dunham

  • Global signatures of protein and mRNA expression levels

    Raquel de Sousa Abreu;Luiz O. Penalva;Edward M. Marcotte;Christine Vogel

  • miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling.

    Alberto Dávalos;Leigh Goedeke;Peter Smibert;Cristina M. Ramírez

  • Sequence signatures and mRNA concentration can explain two-thirds of protein abundance variation in a human cell line

    Christine Vogel;Raquel de Sousa Abreu;Daijin Ko;Shu-Yun Le

  • Site identification in high-throughput RNA–protein interaction data

    Philip J. Uren;Emad Bahrami-Samani;Suzanne C. Burns;Mei Qiao

  • Before It Gets Started: Regulating Translation at the 5' UTR.

    Patricia R. Araujo;Kihoon Yoon;Daijin Ko;Andrew D. Smith

  • MicroRNA-16 and MicroRNA-424 Regulate Cell-Autonomous Angiogenic Functions in Endothelial Cells via Targeting Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1

    Aránzazu Chamorro-Jorganes;Elisa Araldi;Luiz O.F. Penalva;Devraj Sandhu

  • RNA Binding Protein Sex-Lethal (Sxl) and Control of Drosophila Sex Determination and Dosage Compensation

    Luiz O. F. Penalva;Lucas Sánchez

  • Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis.

    Zhe Zhu;Zhe Zhu;Pinar Mesci;Pinar Mesci;Jean A. Bernatchez;Ryan C. Gimple

  • Genomic Analyses of Musashi1 Downstream Targets Show a Strong Association with Cancer-related Processes

    Raquel de Sousa Abreu;Patricia C. Sanchez-Diaz;Christine Vogel;Suzanne C. Burns

  • Genomic analyses of the RNA-binding protein Hu antigen R (HuR) identify a complex network of target genes and novel characteristics of its binding sites.

    Philip J. Uren;Suzanne C. Burns;Jianhua Ruan;Kusum K. Singh

  • RIP-Chip analysis: RNA-Binding Protein Immunoprecipitation-Microarray (Chip) Profiling.

    Ritu Jain;Tiffany Devine;Ajish D. George;Sridar V. Chittur

  • Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma

    Bruna R. Correa;Patricia Rosa de Araujo;Mei Qiao;Suzanne C. Burns

  • Integrating shotgun proteomics and mRNA expression data to improve protein identification

    Smriti R. Ramakrishnan;Christine Vogel;John T. Prince;Zhihua Li

  • Riborex: fast and flexible identification of differential translation from Ribo-seq data

    Wenzheng Li;Weili Wang;Philip J Uren;Luiz O F Penalva

  • IGF2BP3 Modulates the Interaction of Invasion-Associated Transcripts with RISC

    Hanane Ennajdaoui;Hanane Ennajdaoui;Jonathan M. Howard;Timothy Sterne-Weiler;Timothy Sterne-Weiler;Fereshteh Jahanbani;Fereshteh Jahanbani

  • The RNA-Binding Protein Musashi1 Affects Medulloblastoma Growth via a Network of Cancer-Related Genes and Is an Indicator of Poor Prognosis

    Dat T. Vo;Dharmalingam Subramaniam;Marc Remke;Marc Remke;Marc Remke;Tarea L. Burton

  • The oncogenic RNA-binding protein Musashi1 is regulated by tumor suppressor miRNAs.

    Dat T. Vo;Mei Qiao;Andrew D. Smith;Suzanne C. Burns

Frequent Co-Authors

Andrew D. Smith
Andrew D. Smith University of Southern California
Edward M. Marcotte
Edward M. Marcotte The University of Texas at Austin
Helder I. Nakaya
Helder I. Nakaya Universidade de São Paulo
Vishwanath R. Iyer
Vishwanath R. Iyer The University of Texas at Austin
Juan Valcárcel
Juan Valcárcel Institució Catalana de Recerca i Estudis Avançats
Peggy J. Farnham
Peggy J. Farnham University of Southern California
Gregory J. Hannon
Gregory J. Hannon University of Cambridge
Bradley E. Bernstein
Bradley E. Bernstein Broad Institute

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