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Biology and Biochemistry

D-Index
59
Citations
11039
World Ranking
12690
National Ranking
5409

Research.com Recognitions

  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Laurinda A. Jaffe is affiliated with the University of Connecticut Health Center in the United States. Their research spans key areas within medicine, particularly focusing on reproductive medicine and biochemistry, genetics, and molecular biology. The scientific work covers various subfields such as reproductive medicine, public health, environmental and occupational health, molecular biology, genetics, and oncology.

The scientist's publications address a range of topics, prominently including reproductive biology and fertility, ovarian function and disorders, sperm and testicular function, fibroblast growth factor research, connective tissue disorders research, peptidase inhibition and analysis, and reproductive system and pregnancy.

Laurinda A. Jaffe has published recent papers such as:

  • Cellular Heterogeneity of the Luteinizing Hormone Receptor and Its Significance for Cyclic GMP Signaling in Mouse Preovulatory Follicles (2020, Endocrinology)
  • Phosphatase inhibition by LB-100 enhances BMN-111 stimulation of bone growth (2021, JCI Insight)
  • Luteinizing hormone stimulates ingression of mural granulosa cells within the mouse preovulatory follicle (2023, Biology of Reproduction)
  • Kisspeptin-54 injection induces a physiological luteinizing hormone surge and ovulation in mice (2021, Biology of Reproduction)
  • Phosphatases modified by LH signaling in ovarian follicles: testing their role in regulating the NPR2 guanylyl cyclase (2023, Biology of Reproduction)

Frequent coauthors working closely with Jaffe include Tracy F. Uliasz, Jeremy R. Egbert, C. M. Owen, Katie M. Lowther, and Siu-Pok Yee.

The main publication venues for Laurinda A. Jaffe's work comprise:

  • Biology of Reproduction
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Endocrinology
  • JCI Insight
  • Academic Medicine

Laurinda A. Jaffe received recognition as a Fellow of the American Association for the Advancement of Science (AAAS) in 2007.

Best Publications

  • Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte.

    Rachael P. Norris;William J. Ratzan;Marina Freudzon;Lisa M. Mehlmann

  • Fast block to polyspermy in sea urchin eggs is electrically mediated

    Laurinda A. Jaffe

  • Egg activation at fertilization: where it all begins.

    Linda L Runft;Laurinda A Jaffe;Lisa M Mehlmann

  • The Gs-linked receptor GPR3 maintains meiotic arrest in mammalian oocytes.

    Lisa M. Mehlmann;Yoshinaga Saeki;Shigeru Tanaka;Thomas J. Brennan

  • Electrical properties of egg cell membranes.

    Susumu Hagiwara;Laurinda A. Jaffe

  • Meiotic Arrest in the Mouse Follicle Maintained by a Gs Protein in the Oocyte

    Lisa M. Mehlmann;Teresa L. Z. Jones;Laurinda A. Jaffe

  • Luteinizing hormone causes MAP kinase-dependent phosphorylation and closure of connexin 43 gap junctions in mouse ovarian follicles: One of two paths to meiotic resumption

    Rachael P. Norris;Marina Freudzon;Lisa M. Mehlmann;Ann E. Cowan

  • Organization of the sea urchin egg endoplasmic reticulum and its reorganization at fertilization.

    M Terasaki;L A Jaffe

  • Regulation of cortical vesicle exocytosis in sea urchin eggs by inositol 1,4,5-trisphosphate and GTP-binding protein.

    P R Turner;L A Jaffe;A Fein

  • Fertilization increases the polyphosphoinositide content of sea urchin eggs.

    Paul R. Turner;Michael P. Sheetz;Laurinda A. Jaffe

  • Reorganization of the endoplasmic reticulum during meiotic maturation of the mouse oocyte.

    Lisa M. Mehlmann;Mark Terasaki;Laurinda A. Jaffe;Douglas Kline

  • Regulation of Mammalian Oocyte Meiosis by Intercellular Communication Within the Ovarian Follicle

    Laurinda A. Jaffe;Jeremy R. Egbert

  • 6 – Polyspermy-Preventing Mechanisms

    Laurinda A. Jaffe

  • Actin, microvilli, and the fertilization cone of sea urchin eggs.

    L G Tilney;L A Jaffe

  • Luteinizing hormone reduces the activity of the NPR2 guanylyl cyclase in mouse ovarian follicles, contributing to the cyclic GMP decrease that promotes resumption of meiosis in oocytes.

    Jerid W. Robinson;Meijia Zhang;Leia C. Shuhaibar;Rachael P. Norris

  • Development of calcium release mechanisms during starfish oocyte maturation.

    Kazuyoshi Chiba;Raymond T. Kado;Laurinda A. Jaffe;Laurinda A. Jaffe

  • Calcium Release at Fertilization of Xenopus Eggs Requires Type I IP3 Receptors, but Not SH2 Domain-Mediated Activation of PLCγ or Gq-Mediated Activation of PLCβ

    Linda L Runft;James Watras;Laurinda A Jaffe

  • Calcium release at fertilization in starfish eggs is mediated by phospholipase Cgamma.

    David J. Carroll;Chodavarapu S. Ramarao;Lisa M. Mehlmann;Serge Roche

  • SH2 Domain-Mediated Activation of Phospholipase Cγ Is Not Required to Initiate Ca2+Release at Fertilization of Mouse Eggs☆

    Lisa M. Mehlmann;Graham Carpenter;Sue Goo Rhee;Laurinda A. Jaffe

  • Absence of an electrical polyspermy block in the mouse.

    Laurinda A. Jaffe;Andrew P. Sharp;Don P. Wolf

Frequent Co-Authors

Mark Terasaki
Mark Terasaki University of Connecticut Health Center
Viacheslav O. Nikolaev
Viacheslav O. Nikolaev Universität Hamburg
Robert Feil
Robert Feil University of Tübingen
Andreas S. Tolias
Andreas S. Tolias Baylor College of Medicine
Linda Z. Holland
Linda Z. Holland University of California, San Diego
Gregory S. Kopf
Gregory S. Kopf University of Pennsylvania
John J. Eppig
John J. Eppig Jackson Laboratory
Arthur R. Hand
Arthur R. Hand University of Connecticut
Andreas Papapetropoulos
Andreas Papapetropoulos National and Kapodistrian University of Athens
Hengming Ke
Hengming Ke University of North Carolina at Chapel Hill

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