World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
10705
World Ranking
15070
National Ranking
1189

John Parrington publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where John Parrington sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 182 publications — 42nd percentile

42% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

John Parrington D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where John Parrington sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 55 D-Index — 25th percentile

25% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

John Parrington is affiliated with the University of Oxford in the United Kingdom. Their research spans multiple interconnected fields, primarily within biochemistry, genetics, molecular biology, and medicine. They have contributed notably to subfields such as molecular biology, physiology, sensory systems, epidemiology, and genetics.

Their work covers a variety of main topics including:

  • Calcium signaling and nucleotide metabolism
  • CRISPR and Genetic Engineering
  • Ion Channels and Receptors
  • Pluripotent Stem Cells Research
  • Adenosine and Purinergic Signaling
  • Animal Genetics and Reproduction
  • Autophagy in Disease and Therapy

Among their recent publications are:

  • "Targeting Two-Pore Channels: Current Progress and Future Challenges," 2020, Trends in Pharmacological Sciences
  • "Loss of Two-Pore Channel 2 (TPC2) Expression Increases the Metastatic Traits of Melanoma Cells by a Mechanism Involving the Hippo Signalling Pathway and Store-Operated Calcium Entry," 2020, Cancers
  • "Generation of Nonmosaic, Two-Pore Channel 2 Biallelic Knockout Pigs in One Generation by CRISPR-Cas9 Microinjection Before Oocyte Insemination," 2021, The CRISPR Journal
  • "Comparative study of preimplantation development following distinct assisted oocyte activation protocols in a PLC-zeta knockout mouse model," 2020, Molecular Human Reproduction
  • "Deciphering the Role of Ca2+ Signalling in Cancer Metastasis: From the Bench to the Bedside," 2021, Cancers

Frequent co-authors collaborating with Parrington include:

  • Abeer Alharbi
  • Ali Hanbashi
  • Ali Alhoshani
  • Antonella D'Amore
  • Xuhui Jin

John Parrington has published regularly in scientific venues such as:

  • Cancers
  • Cancer Research
  • Trends in Pharmacological Sciences
  • The CRISPR Journal
  • Cell Calcium

In addition to research articles, Parrington has published books with notable academic publishers, including:

  • Redesigning Life, Oxford University Press, 2020
  • Cognitive Science, WORLD SCIENTIFIC (EUROPE) eBooks, expected 2025

Best Publications

  • PLC zeta: a sperm-specific trigger of Ca(2+) oscillations in eggs and embryo development.

    Christopher Matthew Saunders;Mark Graham Larman;John Parrington;Llewellyn J. Cox

  • NAADP mobilizes calcium from acidic organelles through two-pore channels

    Peter J. Calcraft;Margarida Ruas;Zui Pan;Xiaotong Cheng

  • Calcium oscillations in mammalian eggs triggered by a soluble sperm protein

    J Parrington;K Swann;V I Shevchenko;A K Sesay

  • Human sperm devoid of PLC, zeta 1 fail to induce Ca2+ release and are unable to initiate the first step of embryo development

    Sook-Young Yoon;Teru Jellerette;Ana Maria Salicioni;Hoi Chang Lee

  • Reduced amounts and abnormal forms of phospholipase C zeta (PLCzeta) in spermatozoa from infertile men.

    E. Heytens;J. Parrington;K. Coward;K. Coward;C. Young

  • Purified TPC Isoforms Form NAADP Receptors with Distinct Roles for Ca2+ Signaling and Endolysosomal Trafficking

    Margarida Ruas;Katja Rietdorf;Abdelilah Arredouani;Lianne C. Davis

  • Oocyte activation, phospholipase C zeta and human infertility

    J Kashir;B Heindryckx;C Jones;P De Sutter

  • Gamete physiology, fertilization and egg activation in teleost fish

    K Coward;N R Bromage;O Hibbitt;J Parrington

  • TPC2 Is a Novel NAADP-sensitive Ca2+ Release Channel, Operating as a Dual Sensor of Luminal pH and Ca2+

    Samantha Jane Pitt;Tim M Funnell;Mano Sitsapesan;Elisa Venturi

  • Expression of Ca2+-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells

    Margarida Ruas;Lianne C. Davis;Cheng Chang Chen;Anthony J. Morgan

  • Nicotinic acid adenine dinucleotide phosphate mediates Ca2+ signals and contraction in arterial smooth muscle via a two-pool mechanism.

    François-Xavier Boittin;Antony Galione;A. Mark Evans

  • Bidirectional Ca2+ signaling occurs between the endoplasmic reticulum and acidic organelles

    Anthony J. Morgan;Lianne C. Davis;Siegfried K.T.Y. Wagner;Alexander M. Lewis

  • NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killing.

    Lianne C. Davis;Anthony J. Morgan;Ji Li Chen;Charlotte M. Snead

  • The pattern of localization of the putative oocyte activation factor, phospholipase Czeta, in uncapacitated, capacitated, and ionophore-treated human spermatozoa.

    P Grasa;K Coward;K Coward;C Young;J Parrington

  • VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2-dependent Ca2+ signaling

    Annarita Favia;Marianna Desideri;Guido Gambara;Alessio D’Alessio

  • Calcium signaling via two-pore channels: local or global, that is the question.

    Michael X. Zhu;Jianjie Ma;John Parrington;Peter J. Calcraft

  • A maternally inherited autosomal point mutation in human phospholipase C zeta (PLCζ) leads to male infertility

    Junaid Kashir;Michalis Konstantinidis;Celine Jones;Bernadette Lemmon

  • Expression of Inositol 1,4,5-Trisphosphate Receptors in Mouse Oocytes and Early Embryos: The Type I Isoform Is Upregulated in Oocytes and Downregulated after Fertilization

    J Parrington;S Brind;H De Smedt;R Gangeswaran

  • Phospholipase C zeta undergoes dynamic changes in its pattern of localization in sperm during capacitation and the acrosome reaction.

    Claire Young;Patricia Grasa;Kevin Coward;Lianne C. Davis

  • PLCζ is the physiological trigger of the Ca2+ oscillations that induce embryogenesis in mammals but conception can occur in its absence.

    Alaa Hachem;Jonathan Godwin;Margarida Ruas;Hoi Chang Lee

Frequent Co-Authors

Antony Galione
Antony Galione University of Oxford
Karl Swann
Karl Swann Cardiff University
Michael X. Zhu
Michael X. Zhu The University of Texas Health Science Center at Houston
Grant C. Churchill
Grant C. Churchill University of Oxford
Keith T. Jones
Keith T. Jones University of Sussex
Rafael A. Fissore
Rafael A. Fissore University of Massachusetts Amherst
Jianjie Ma
Jianjie Ma The Ohio State University
Dieter Deforce
Dieter Deforce Ghent University
Luc Leybaert
Luc Leybaert Ghent University
Gary M. Wessel
Gary M. Wessel Brown University

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