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Biology and Biochemistry

D-Index
67
Citations
39420
World Ranking
8022
National Ranking
3633

Research.com Recognitions

  • 2009 - Fellow of Alfred P. Sloan Foundation

Overview

Haoxing Xu is affiliated with the University of Michigan-Ann Arbor in the United States. Their research spans multiple fields including biochemistry, genetics, molecular biology, and medicine, with significant contributions to physiology, epidemiology, molecular biology, cell biology, and cellular and molecular neuroscience.

The main topics of Haoxing Xu's work include:

  • Calcium signaling and nucleotide metabolism
  • Autophagy in Disease and Therapy
  • Cellular transport and secretion
  • Ion Channels and Receptors
  • Herbal Medicine Research Studies
  • Lysosomal Storage Disorders Research
  • Adenosine and Purinergic Signaling

Haoxing Xu's recent papers demonstrate a focus on pharmacology, cellular mechanisms, and lysosomal function. Notable publications include:

  • THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels (2021), published in British Journal of Pharmacology
  • LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury (2020), published in Nature Cell Biology
  • Parkinson's disease-risk protein TMEM175 is a proton-activated proton channel in lysosomes (2022), published in Cell
  • The Concise Guide to PHARMACOLOGY 2023/24: Ion channels (2023), published in British Journal of Pharmacology
  • Sulforaphane Activates a lysosome-dependent transcriptional program to mitigate oxidative stress (2020), published in Autophagy

Frequent co-authors collaborating with Haoxing Xu include:

  • Meiqin Hu
  • Lixia Yue
  • Rajan Sah
  • Markus Delling
  • Kotdaji Ha

Their work is published in several key venues, with multiple publications in each of the following journals:

  • IUPHAR/BPS Guide to Pharmacology CITE (6 publications)
  • Autophagy (3 publications)
  • The Journal of Cell Biology (3 publications)
  • British Journal of Pharmacology (2 publications)
  • Nature Cell Biology (2 publications)

Haoxing Xu was recognized with the award of Fellow of the Alfred P. Sloan Foundation in 2009.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

    Diego L. Medina;Simone Di Paola;Ivana Peluso;Andrea Armani

  • TRPV3 is a calcium-permeable temperature-sensitive cation channel

    Haoxing Xu;I. Scott Ramsey;Suhas A. Kotecha;Magdalene M. Moran

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels

    Haoxing Xu;Markus Delling;Markus Delling;Janice C Jun;Janice C Jun;David E Clapham;David E Clapham

  • PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome

    Xian Ping Dong;Dongbiao Shen;Xiang Wang;Taylor Dawson

  • The Type IV Mucolipidosis-Associated Protein TRPML1 is an Endolysosomal Iron Release Channel

    Xian-Ping Dong;Xiping Cheng;Eric Mills;Markus Delling

  • A prokaryotic voltage-gated sodium channel.

    Dejian Ren;Betsy Navarro;Haoxing Xu;Lixia Yue

  • TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes.

    Xiang Wang;Xiaoli Zhang;Xian Ping Dong;Mohammad Samie

  • Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism.

    Haoxing Xu;Nathaniel T. Blair;David E. Clapham

  • Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release

    Dongbiao Shen;Xiang Wang;Xinran Li;Xiaoli Zhang

  • MCOLN1 is a ROS sensor in lysosomes that regulates autophagy

    Xiaoli Zhang;Xiping Cheng;Lu Yu;Junsheng Yang;Junsheng Yang

  • Phosphatidylinositol 3-Kinase Activates ERK in Primary Sensory Neurons and Mediates Inflammatory Heat Hyperalgesia through TRPV1 Sensitization

    Zhi Ye Zhuang;Haoxing Xu;David E. Clapham;Ru Rong Ji

  • TRP ion channels in the nervous system.

    Magdalene M Moran;Haoxing Xu;David E Clapham

  • A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation

    Xinran Li;Nicholas Rydzewski;Ahmad Hider;Xiaoli Zhang

  • A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion

    Yuxuan Miao;Guojie Li;Xiaoli Zhang;Haoxing Xu

  • Mechanisms of Brain Iron Transport: Insight into Neurodegeneration and CNS Disorders

    Eric Mills;Xian Ping Dong;Fudi Wang;Haoxing Xu

  • TRP Channel Regulates EGFR Signaling in Hair Morphogenesis and Skin Barrier Formation

    Xiping Cheng;Jie Jin;Lily Hu;Dongbiao Shen

  • A TRP Channel in the Lysosome Regulates Large Particle Phagocytosis via Focal Exocytosis

    Mohammad Samie;Xiang Wang;Xiaoli Zhang;Andrew Goschka

Frequent Co-Authors

David E. Clapham
David E. Clapham Howard Hughes Medical Institute
Marc Ferrer
Marc Ferrer National Institutes of Health
Evelina Gatti
Evelina Gatti Aix-Marseille University
Sergio Lavandero
Sergio Lavandero University of Chile
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Steven Finkbeiner
Steven Finkbeiner University of California, San Francisco
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Nancy C. Andrews
Nancy C. Andrews Duke University
Maurizio Molinari
Maurizio Molinari Universita della Svizzera Italiana
Patrick A. Lewis
Patrick A. Lewis University College London

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