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Biology and Biochemistry

D-Index
61
Citations
43123
World Ranking
11075
National Ranking
4786

Overview

Rosa Puertollano is affiliated with the National Institutes of Health in the United States and has a research portfolio focused primarily on biochemistry, genetics, molecular biology, and medicine. Their work addresses several interrelated subfields including physiology, molecular biology, epidemiology, cell biology, and immunology.

The scientist's research explores key topics such as autophagy in disease and therapy, lysosomal storage disorders, calcium signaling and nucleotide metabolism, cellular transport and secretion, glycogen storage diseases and myoclonus, ubiquitin and proteasome pathways, as well as the role of immune cells in cancer.

Rosa Puertollano has contributed to numerous papers published in well-known scientific journals. Some recent examples include:

  • How Lysosomes Sense, Integrate, and Cope with Stress (2020) in Trends in Biochemical Sciences
  • Impaired autophagy: The collateral damage of lysosomal storage disorders (2020) in EBioMedicine
  • TRPML2 is an osmo/mechanosensitive cation channel in endolysosomal organelles (2020) in Science Advances
  • SnapShot: Lysosomal Storage Diseases (2020) in Cell
  • Enzyme Replacement Therapy Can Reverse Pathogenic Cascade in Pompe Disease (2020) in Molecular Therapy - Methods & Clinical Development

Frequent coauthors collaborating with Puertollano include Nina Raben, José A. Martina, Naresh Kumar Meena, Eutteum Jeong, and Pablo S. Contreras. Their collective work has been published in several recurring venues such as Autophagy, EMBO Reports, Nature Communications, bioRxiv (Cold Spring Harbor Laboratory), and Molecular Genetics and Metabolism.

The combination of extensive work in autophagy and lysosomal storage disorders, alongside investigations into molecular mechanisms like calcium signaling and cellular transport, places Puertollano's research at the intersection of foundational biochemistry and translational medicine. This multidisciplinary approach reflects an engagement with both the molecular basis of disease and potential therapeutic avenues.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB

    Jose A. Martina;Yong Chen;Marjan Gucek;Rosa Puertollano

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Transcriptional Activation of Lysosomal Exocytosis Promotes Cellular Clearance

    Diego L Medina;Alessandro Fraldi;Valentina Bouche;Fabio Annunziata

  • The Nutrient-Responsive Transcription Factor TFE3 Promotes Autophagy, Lysosomal Biogenesis, and Clearance of Cellular Debris

    José A. Martina;Heba I. Diab;Li Lishu;Lim Jeong-A

  • Ggas A Family of Adp Ribosylation Factor-Binding Proteins Related to Adaptors and Associated with the Golgi Complex

    Esteban C. Dell'Angelica;Rosa Puertollano;Chris Mullins;Rubén C. Aguilar

  • Sorting of mannose 6-phosphate receptors mediated by the GGAs.

    Rosa Puertollano;Rubén C. Aguilar;Inna Gorshkova;Robert J. Crouch

  • Autophagy in lysosomal storage disorders

    Andrew P. Lieberman;Rosa Puertollano;Nina Raben;Susan Ann Slaugenhaupt

  • The complex relationship between TFEB transcription factor phosphorylation and subcellular localization.

    Rosa Puertollano;Shawn M Ferguson;James Brugarolas;Andrea Ballabio

  • TFEB and TFE3: Linking Lysosomes to Cellular Adaptation to Stress*

    Nina Raben;Rosa Puertollano

  • Transcription factor EB (TFEB) is a new therapeutic target for Pompe disease

    Carmine Spampanato;Erin Feeney;Lishu Li;Monica Cardone

  • Rag GTPases mediate amino acid–dependent recruitment of TFEB and MITF to lysosomes

    Jose A. Martina;Rosa Puertollano

  • The GGAs Promote ARF-Dependent Recruitment of Clathrin to the TGN

    Rosa Puertollano;Paul A Randazzo;John F Presley;Lisa M Hartnell

  • TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages

    Nunzia Pastore;Owen A. Brady;Heba I. Diab;José A. Martina

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • TFEB and TFE3 are novel components of the integrated stress response

    José A Martina;Heba I Diab;Owen A Brady;Rosa Puertollano

  • Interactions of GGA3 with the ubiquitin sorting machinery

    Rosa Puertollano;Juan S Bonifacino

  • Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics.

    Sylwia Wasiak;Valerie Legendre-Guillemin;Rosa Puertollano;Francois Blondeau

Frequent Co-Authors

Nina Raben
Nina Raben National Institutes of Health
Miguel A. Alonso
Miguel A. Alonso Spanish National Research Council
Andrea Ballabio
Andrea Ballabio Baylor College of Medicine
Juan S. Bonifacino
Juan S. Bonifacino National Institutes of Health
Sergio Lavandero
Sergio Lavandero University of Chile
Evelina Gatti
Evelina Gatti Aix-Marseille University
Boris Zhivotovsky
Boris Zhivotovsky Karolinska Institute
Xiao Ming Yin
Xiao Ming Yin Indiana University
Philippe Pierre
Philippe Pierre Aix-Marseille University
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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