What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Cell membrane
Shmuel Muallem spends much of his time researching Cell biology, Biochemistry, Endocrinology, Internal medicine and Voltage-dependent calcium channel.
His research in Cell biology intersects with topics in Secretion, TRPC Cation Channels and Cystic fibrosis transmembrane conductance regulator.
His Biochemistry study which covers Biophysics that intersects with Inositol trisphosphate receptor and Transduction.
The study incorporates disciplines such as Salivary gland, Calcium and Ion transporter in addition to Endocrinology.
His study connects Signal transduction and Internal medicine.
The various areas that Shmuel Muallem examines in his Voltage-dependent calcium channel study include Gating, Lysosome, Calcium channel and Two-pore channel.
His most cited work include:
- Functional interaction between InsP3 receptors and store-operated Htrp3 channels. (564 citations)
- STIM1 carboxyl-terminus activates native SOC, I crac and TRPC1 channels (561 citations)
- SOAR and the polybasic STIM1 domains gate and regulate Orai channels (533 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Cell biology, Internal medicine, Endocrinology, Biophysics and Biochemistry.
His Cell biology study combines topics in areas such as Secretion, Receptor and TRPC.
The TRPC study which covers STIM1 that intersects with Gating and Voltage-dependent calcium channel.
His Endocrinology research incorporates themes from Agonist and Calcium.
Shmuel Muallem interconnects Extracellular, Membrane transport, Ion transporter, Inositol and Intracellular in the investigation of issues within Biophysics.
In his study, which falls under the umbrella issue of Biochemistry, DIDS is strongly linked to Cotransporter.
He most often published in these fields:
- Cell biology (49.33%)
- Internal medicine (34.00%)
- Endocrinology (33.00%)
What were the highlights of his more recent work (between 2012-2020)?
- Cell biology (49.33%)
- Internal medicine (34.00%)
- Endocrinology (33.00%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Cell biology, Internal medicine, Endocrinology, STIM1 and Biochemistry.
The Cell biology study combines topics in areas such as Secretion, Cell membrane and Voltage-dependent calcium channel.
His Secretion research integrates issues from Epithelium, Salivary gland and N-terminus.
In the subject of general Endocrinology, his work in Acetylcholine, Nitric oxide and Vasoconstriction is often linked to Endothelial stem cell and Mesenteric arteries, thereby combining diverse domains of study.
His work carried out in the field of STIM1 brings together such families of science as Gating, Lipid microdomain and TRPC.
His Biochemistry research includes elements of Cotransporter and Function.
Between 2012 and 2020, his most popular works were:
- Convergent regulation of the lysosomal two‐pore channel‐2 by Mg2+, NAADP, PI(3,5)P2 and multiple protein kinases (123 citations)
- Translocation between PI(4,5)P2-poor and PI(4,5)P2-rich microdomains during store depletion determines STIM1 conformation and Orai1 gating (88 citations)
- The STIM1 CTID domain determines access of SARAF to SOAR to regulate Orai1 channel function. (82 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Cell membrane
Shmuel Muallem focuses on Cell biology, STIM1, Voltage-dependent calcium channel, Biochemistry and Secretion.
His biological study spans a wide range of topics, including Binding protein and Lysosome.
In his research on the topic of STIM1, TRPC is strongly related with Gating.
Specifically, his work in Biochemistry is concerned with the study of SLC26A6.
Shmuel Muallem has researched Secretion in several fields, including Signal transduction, G protein-coupled receptor, Transporter, Intracellular and Salivary gland.
His Salivary gland study integrates concerns from other disciplines, such as Endocrinology, Cystic fibrosis, Cystic fibrosis transmembrane conductance regulator and Pancreatitis.
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