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Biology and Biochemistry

D-Index
64
Citations
15951
World Ranking
9591
National Ranking
732

Overview

Brian J. Sutton is affiliated with King's College London in the United Kingdom. Their research spans multiple fields within biomedical sciences, with a focus on immunology and molecular biology.

The main fields of study for the scientist include:

  • Medicine
  • Immunology and Microbiology

The subfields of study cover:

  • Immunology
  • Radiology, Nuclear Medicine and Imaging
  • Molecular Biology
  • Immunology and Allergy
  • Physiology

Key topics explored in their work involve:

  • Monoclonal and Polyclonal Antibodies Research
  • Glycosylation and Glycoproteins Research
  • T-cell and B-cell Immunology
  • Asthma and respiratory diseases
  • Mast cells and histamine
  • Immune Cell Function and Interaction
  • Cell Adhesion Molecules Research

The scientist has contributed to several publications with recent papers including:

  • "IgE to epitopes of Ara h 2 enhance the diagnostic accuracy of Ara h 2-specific IgE" (2020, Allergy)
  • "IgE, IgE Receptors and Anti-IgE Biologics: Protein Structures and Mechanisms of Action" (2023, Annual Review of Immunology)
  • "Differences between Human and Mouse IgM Fc Receptor (FcµR)" (2021, International Journal of Molecular Sciences)
  • "Identification of Amino Acid Residues in Human IgM Fc Receptor (FcµR) Critical for IgM Binding" (2021, Frontiers in Immunology)
  • "Crystal structures of the human IgD Fab reveal insights into CH1 domain diversity" (2023, Molecular Immunology)

Frequent co-authors they have collaborated with are:

  • James M. McDonnell
  • Andrew J. Beavil
  • Hannah J. Gould
  • Anna M. Davies
  • Rosaleen A. Calvert

Publication venues where their work appears most regularly include:

  • Frontiers in Immunology
  • Biochemical and Biophysical Research Communications
  • Annual Review of Immunology
  • Allergy
  • International Journal of Molecular Sciences

Best Publications

  • Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG.

    R. B. Parekh;R. A. Dwek;B. J. Sutton;D. L. Fernandes

  • IgE in allergy and asthma today

    Hannah J. Gould;Brian J. Sutton

  • Regulation of Cutaneous Malignancy by γδ T Cells

    Michael Girardi;David E. Oppenheim;Carrie R. Steele;Julia M. Lewis

  • The biology of IGE and the basis of allergic disease.

    Hannah J. Gould;Brian J. Sutton;Andrew J. Beavil;Rebecca L. Beavil

  • Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: Structural basis for recognition of B-cell receptors and superantigen activity

    Marc Graille;Enrico A. Stura;Adam L. Corper;Brian J. Sutton

  • Crystal structure of the zinc-dependent beta-lactamase from Bacillus cereus at 1.9 A resolution: binuclear active site with features of a mononuclear enzyme.

    Stella Maris Fabiane;Maninder K. Sohi;Tommy Wan;David J. Payne

  • Molecular model of a lattice of signalling proteins involved in bacterial chemotaxis

    Thomas Simon Shimizu;Nicolas Le Novere;Matthew Daniel Levin;Andrew J. Beavil

  • Structure of human IgM rheumatoid factor Fab bound to its autoantigen IgG Fc reveals a novel topology of antibody-antigen interaction.

    Adam L. Corper;Maninder K. Sohi;Vincent R. Bonagura;Michael Steinitz

  • Identification of Contact Residues and Definition of the CAR-Binding Site of Adenovirus Type 5 Fiber Protein

    Ian Kirby;Elizabeth Davison;Andrew J. Beavil;Cecilia P. C. Soh

  • Solution structure of human and mouse immunoglobulin M by synchrotron X-ray scattering and molecular graphics modelling. A possible mechanism for complement activation.

    Stephen J. Perkins;Adam S. Nealis;Brian J. Sutton;Arnold Feinstein

  • The crystal structure of IgE Fc reveals an asymmetrically bent conformation

    Tommy Wan;Rebecca L. Beavil;Stella M. Fabiane;Andrew J. Beavil

  • The structure of human CD23 and its interactions with IgE and CD21

    Richard G. Hibbert;Peter Teriete;Gabrielle J. Grundy;Rebecca L. Beavil

  • Alpha-helical coiled-coil stalks in the low-affinity receptor for IgE (Fc epsilon RII/CD23) and related C-type lectins.

    Andrew J. Beavil;Rebecca L. Edmeades;Hannah J. Gould;Brian J. Sutton

  • Complex between Peptostreptococcus magnus protein L and a human antibody reveals structural convergence in the interaction modes of Fab binding proteins

    Marc Graille;Enrico A. Stura;Nicholas G. Housden;Jennifer A. Beckingham

  • Tertiary structural similarity between a class A β -lactamase and a penicillin-sensitive D-alanyl carboxypeptidase-transpeptidase

    B. Samraoui;B. Samraoui;B. Samraoui;B. J. Sutton;B. J. Sutton;R. J. Todd;R. J. Todd;P. J. Artymiuk;P. J. Artymiuk

  • Mutations in the DG Loop of Adenovirus Type 5 Fiber Knob Protein Abolish High-Affinity Binding to Its Cellular Receptor CAR

    Ian Kirby;Elizabeth Davison;Andrew J. Beavil;Cecilia P. C. Soh

  • Human IgG4: a structural perspective.

    Anna Marie Davies;Anna Marie Davies;Brian Sutton;Brian Sutton

  • An X-ray-crystallographic study of beta-lactamase II from Bacillus cereus at 0.35 nm resolution.

    B J Sutton;P J Artymiuk;A E Cordero-Borboa;C Little

  • The structure and origin of rheumatoid factors

    Brian Sutton;Adam Corper;Vincent Bonagura;Michael Taussig

  • Participation of the N-terminal region of Cepsilon3 in the binding of human IgE to its high-affinity receptor FcepsilonRI.

    Alistair J. Henry;Justin P. D. Cook;James M. McDonnell;Graham A. Mackay

Frequent Co-Authors

Hannah J. Gould
Hannah J. Gould King's College London
Michael J. Taussig
Michael J. Taussig Babraham Institute
Enrico A. Stura
Enrico A. Stura University of Paris-Saclay
Raymond J. Owens
Raymond J. Owens University of Oxford
Paul Brown
Paul Brown National Institutes of Health
Rob C. Aalberse
Rob C. Aalberse University of Amsterdam
Theo Rispens
Theo Rispens University of Amsterdam
Sophia N. Karagiannis
Sophia N. Karagiannis King's College London
Robin J. Leatherbarrow
Robin J. Leatherbarrow Imperial College London

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