Enrico A. Stura

What is he best known for?

The fields of study he is best known for:

• Enzyme
• Gene
• Amino acid

Enrico A. Stura mostly deals with Stereochemistry, Biochemistry, Peptide sequence, Peptide and Protein structure. His Stereochemistry research is multidisciplinary, incorporating perspectives in Cyclase, MHC class I, Catalysis, Substrate and Binding site. His biological study spans a wide range of topics, including Epitope, Crystallization and Structure–activity relationship.

He has researched Peptide in several fields, including Receptor, Alanine, Molecular biology and T-cell receptor. His Molecular biology course of study focuses on Antigen and Protein A, B-cell receptor and Antibody. His studies deal with areas such as V3 loop and Lipid bilayer fusion as well as Protein structure.

His most cited work include:

• Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb. (785 citations)
• Crystal Structure of Mouse CD1: An MHC-Like Fold with a Large Hydrophobic Binding Groove (590 citations)
• Functional Mimicry of a Protein Hormone by a Peptide Agonist: The EPO Receptor Complex at 2.8 Å (571 citations)

What are the main themes of his work throughout his whole career to date?

Enrico A. Stura focuses on Stereochemistry, Biochemistry, Crystallography, Crystallization and Crystal structure. His Stereochemistry research incorporates elements of Binding site, Active site, Protein structure, Monoclonal antibody and Peptide. His Protein structure research is multidisciplinary, relying on both Biophysics and Peptide sequence.

While the research belongs to areas of Monoclonal antibody, Enrico A. Stura spends his time largely on the problem of Antigen, intersecting his research to questions surrounding Virology. The study of Biochemistry is intertwined with the study of Antibody in a number of ways. The study incorporates disciplines such as Molecular biology, Erythropoietin and Cell biology in addition to Receptor.

He most often published in these fields:

• Stereochemistry (32.51%)
• Biochemistry (29.63%)
• Crystallography (19.75%)

What were the highlights of his more recent work (between 2014-2019)?

• Transthyretin (5.76%)
• Stereochemistry (32.51%)
• Biochemistry (29.63%)

In recent papers he was focusing on the following fields of study:

Enrico A. Stura mainly investigates Transthyretin, Stereochemistry, Biochemistry, Matrix metalloproteinase and Combinatorial chemistry. His Transthyretin study also includes fields such as

• Tetramer which is related to area like Cooperativity, Cooperative binding, Dimer, Hydrogen bond and Conformational isomerism,
• Fibrillogenesis most often made with reference to Propanoic acid,
• Acetic acid and related Medicinal chemistry,
• Polyethylene glycol which is related to area like Fibril and Ligand,
• Transport protein together with Protein structure. His study focuses on the intersection of Stereochemistry and fields such as Crystallography with connections in the field of Phaser.

His Biochemistry research integrates issues from Chalcone and Cancer research. His Matrix metalloproteinase study incorporates themes from Hydrolase, Carboxylate, Thiourea and Chelation. The Combinatorial chemistry study combines topics in areas such as Crystallization, Organic chemistry and Solubilization.

Between 2014 and 2019, his most popular works were:

• N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity. (34 citations)
• Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition. (33 citations)
• Discovery of a new selective inhibitor of A Disintegrin And Metalloprotease 10 (ADAM-10) able to reduce the shedding of NKG2D ligands in Hodgkin's lymphoma cell models. (28 citations)

In his most recent research, the most cited papers focused on:

• Enzyme
• Gene
• Amino acid

His primary areas of study are Biochemistry, Stereochemistry, Matrix metalloproteinase inhibitor, Matrix metalloproteinase and In vitro. His studies in Biochemistry integrate themes in fields like Cancer research and Lymphoma. Enrico A. Stura has included themes like Peptide, Peptide chemical synthesis, Acid-sensing ion channel and Sodium channel in his Stereochemistry study.

His Matrix metalloproteinase inhibitor research is multidisciplinary, incorporating perspectives in Hydrolase and Structure–activity relationship. Enrico A. Stura focuses mostly in the field of Structure–activity relationship, narrowing it down to matters related to Zinc and, in some cases, Combinatorial chemistry. His work in the fields of In vitro, such as Matrigel, intersects with other areas such as Conjugate and Linker.