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Immunology

D-Index
63
Citations
10982
World Ranking
3073
National Ranking
1439

Overview

Daniel H. Conrad is affiliated with Virginia Commonwealth University in the United States. Their research primarily focuses on immunology and microbiology, with a significant portion of work also related to medicine.

The scientist's work spans multiple subfields, including:

  • Immunology
  • Molecular Biology
  • Epidemiology
  • Immunology and Allergy
  • Parasitology

Central themes in their research include:

  • Immune cells in cancer
  • Epigenetics and DNA Methylation
  • Immune Cell Function and Interaction
  • Immune Response and Inflammation
  • T-cell and B-cell Immunology
  • Vector-borne infectious diseases
  • Asthma and respiratory diseases

Recent publications authored or coauthored by Daniel H. Conrad include:

  • The DNA methyltransferase inhibitor, guadecitabine, targets tumor-induced myelopoiesis and recovers T cell activity to slow tumor growth in combination with adoptive immunotherapy in a mouse model of breast cancer (2020, BMC Immunology)
  • TAO-kinase 3 governs the terminal differentiation of NOTCH2-dependent splenic conventional dendritic cells (2020, Proceedings of the National Academy of Sciences)
  • Binding of Host Cell Surface Protein Disulfide Isomerase by Anaplasma phagocytophilum Asp14 Enables Pathogen Infection (2020, mBio)
  • Immunization against Anaplasma phagocytophilum Adhesin Binding Domains Confers Protection against Infection in the Mouse Model (2020, Infection and Immunity)
  • T cell receptor signaling defines the fate and pathway of ICOS internalization (2020, Biochemistry and Biophysics Reports)

Their work has been published in various journals, with frequent publications appearing in:

  • The Journal of Immunology
  • BMC Immunology
  • Proceedings of the National Academy of Sciences
  • mBio
  • Arthritis Research & Therapy

Daniel H. Conrad has collaborated extensively with several researchers including:

  • Rebecca Martin
  • Anuj Tharakan
  • Matthew Zellner
  • Joseph Lownik
  • Andrea Luker

Best Publications

  • ADAMs 10 and 17 Represent Differentially Regulated Components of a General Shedding Machinery for Membrane Proteins Such as Transforming Growth Factor α, L-Selectin, and Tumor Necrosis Factor α

    Sylvain M. Le Gall;Pierre Bobé;Karina Reiss;Keisuke Horiuchi

  • The proteasome inhibitor bortezomib interacts synergistically with histone deacetylase inhibitors to induce apoptosis in Bcr/Abl+ cells sensitive and resistant to STI571.

    Chunrong Yu;Mohamed Rahmani;Daniel Conrad;Mark Subler

  • Fc epsilon RII/CD23: the low affinity receptor for IgE.

    Daniel H. Conrad

  • ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23

    Gisela Weskamp;Jill W Ford;Jamie Sturgill;Steve Martin

  • A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects

    Jose Gomez-Arroyo;Sheinei J. Saleem;Shiro Mizuno;Aamer A. Syed

  • IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe-/- mice.

    Jing Wang;Xiang Cheng;Xiang Cheng;Mei Xiang Xiang;Mervi Alanne-Kinnunen

  • Characterization of a monoclonal antibody directed against the murine B lymphocyte receptor for IgE.

    Mangala Rao;W. T. Lee;D. H. Conrad

  • Cross-linking Fc receptors stimulate splenic non-B, non-T cells to secrete interleukin 4 and other lymphokines

    S Z Ben-Sasson;G Le Gros;D H Conrad;F D Finkelman

  • Histone Deacetylase Inhibitors Promote STI571-mediated Apoptosis in STI571-sensitive and -resistant Bcr/Abl+ Human Myeloid Leukemia Cells

    Chunrong Yu;Mohamed Rahmani;Jorge Almenara;Mark Subler

  • Murine B-cell stimulatory factor 1 (interleukin 4) increases expression of the Fc receptor for IgE on mouse B cells

    Susan A. Hudak;Sandra O. Gollnick;Daniel H. Conrad;Marilyn R. Kehry

  • IL-4 production by T cells from naive donors. IL-2 is required for IL-4 production.

    S Z Ben-Sasson;G Le Gros;D H Conrad;F D Finkelman

  • ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo

    David R. Gibb;Mohey El Shikh;Dae Joong Kang;Warren J. Rowe

  • A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell–dependent murine model of allergic asthma

    Megan M. Price;Carole A. Oskeritzian;Yves T. Falanga;Kuzhuvelil B. Harikumar

  • Enhanced intestinal transepithelial antigen transport in allergic rats is mediated by IgE and CD23 (FcεRII)

    Ping-Chang Yang;M. Cecilia Berin;Linda C.H. Yu;Daniel H. Conrad

  • Enhanced transepithelial antigen transport in intestine of allergic mice is mediated by IgE/CD23 and regulated by interleukin-4

    Linda C.H. Yu;Ping-Chang Yang;M.Cecilia Berin;Vincenza Di Leo

  • IL-10 suppresses mast cell IgE receptor expression and signaling in vitro and in vivo.

    Sarah Kennedy Norton;Brian Barnstein;Jennifer Brenzovich;Daniel P. Bailey

  • Binding Parameters of the Interaction Between Rat IgE and Rat Mast Cell Receptors

    Daniel H. Conrad;Hervé Bazin;Alec H. Sehon;Arnold Froese

  • Murine follicular dendritic cells and low affinity Fc receptors for IgE (Fc epsilon RII).

    K Maeda;G F Burton;D A Padgett;D H Conrad

  • Aberrant ORM (yeast)–like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice

    Clement Oyeniran;Jamie L. Sturgill;Nitai C. Hait;Wei-Ching Huang

  • Follicular dendritic cells and B cell costimulation.

    G F Burton;D H Conrad;A K Szakal;J G Tew

  • IL-4 induces co-expression of intrinsic membrane IgG1 and IgE by murine B cells stimulated with lipopolysaccharide.

    C M Snapper;F D Finkelman;D Stefany;D H Conrad

  • Infection with Nippostrongylus brasiliensis or injection of anti-IgD antibodies markedly enhances Fc-receptor-mediated interleukin 4 production by non-B, non-T cells.

    D H Conrad;S Z Ben-Sasson;G Le Gros;F D Finkelman

Frequent Co-Authors

John J. Ryan
John J. Ryan Virginia Commonwealth University
Fred D. Finkelman
Fred D. Finkelman University of Cincinnati
Sarah Spiegel
Sarah Spiegel Virginia Commonwealth University
Teruko Ishizaka
Teruko Ishizaka La Jolla Institute For Allergy & Immunology
Paul Dent
Paul Dent Virginia Commonwealth University
Steven Grant
Steven Grant Virginia Commonwealth University
Hannah J. Gould
Hannah J. Gould King's College London
Mohamed Rahmani
Mohamed Rahmani Khalifa University
Achsah D. Keegan
Achsah D. Keegan University of Maryland, Baltimore
Ping-Chang Yang
Ping-Chang Yang Shenzhen University

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